6VRF

ADP bound TTBK2 kinase domain

Summary for 6VRF

Entry DOI	10.2210/pdb6vrf/pdb
Descriptor	Tau-tubulin kinase 2, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (7 entities in total)
Functional Keywords	ttbk2 kinase domain, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	70608.12
Authors	Chodaparambil, J.V.,Marcotte, D.J. (deposition date: 2020-02-07, release date: 2020-06-03, Last modification date: 2023-10-11)
Primary citation	Bao, C.,Bajrami, B.,Marcotte, D.J.,Chodaparambil, J.V.,Kerns, H.M.,Henderson, J.,Wei, R.,Gao, B.,Dillon, G.M. Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms. Cell Mol Neurobiol, 41:669-685, 2021 Cited by PubMed: 32424773 DOI: 10.1007/s10571-020-00875-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation