PDB: 225946 件ウェブページステータス検索Chemie searchBIRD

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2F7X	Protein Kinase A bound to (S)-2-(1H-Indol-3-yl)-1-[5-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine 分子名称: (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE, PKI, inhibitory peptide, ... 著者 Li, Q, Li, T, Zhu, G.D, Gong, J, Claibone, A, Dalton, C, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Bauch, J.L, Marsh, K.C, Bouska, J.J, Arries, S, De Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. 登録日 2005-12-01 公開日 2006-06-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Bioorg.Med.Chem.Lett., 16, 2006
2F7Y	Crystal structure of Molybdenum cofactor biosynthesis protein Mog from Shewanella oneidensis 分子名称: molybdenum cofactor biosynthesis protein Mog 著者 Chang, C, Mulligan, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-12-01 公開日 2006-01-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Molybdenum cofactor biosynthesis protein Mog from Shewanella oneidensis To be Published
2F7Z	Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine 分子名称: (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE, PKI, inhibitory peptide, ... 著者 Li, Q, Woods, K.W, Thomas, S, Zhu, G.D, Packard, G, Fisher, J, Li, T, Gong, J, Dinges, J, Song, X, Abrams, J, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Des Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. 登録日 2005-12-01 公開日 2006-06-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg.Med.Chem.Lett., 16, 2006
2F80	HIV-1 Protease mutant D30N complexed with inhibitor TMC114 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, POL POLYPROTEIN, ... 著者 Kovalevsky, A.Y, Weber, I.T. 登録日 2005-12-01 公開日 2006-03-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006
2F81	HIV-1 Protease mutant L90M complexed with inhibitor TMC114 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ... 著者 Kovalevsky, A.Y, Weber, I.T. 登録日 2005-12-01 公開日 2006-03-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006
2F82	HMG-CoA synthase from Brassica juncea in the apo-form 分子名称: HMG-CoA synthase 著者 Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. 登録日 2005-12-01 公開日 2006-07-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
2F84	Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from P.falciparum 分子名称: PHOSPHATE ION, orotidine monophosphate decarboxylase 著者 Caruthers, J.M, Robein, M, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-12-01 公開日 2005-12-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from Plasmodium falciparum To be Published
2F86	The Association Domain of C. elegans CaMKII 分子名称: Hypothetical protein K11E8.1d 著者 Rosenberg, O.S, Kuriyan, J. 登録日 2005-12-01 公開日 2006-02-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II. Febs J., 273, 2006
2F87	Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus 分子名称: SRP RNA 著者 Okada, K, Takahashi, M, Sakamoto, T, Nakamura, K, Kanai, A, Kawai, G 登録日 2005-12-02 公開日 2006-08-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus Nucleosides Nucleotides Nucleic Acids, 25, 2006
2F88	Solution NMR structure of domain 5 from the Pyaiella littoralis (PL) group II intron 分子名称: D5-PL RNA RIBOZYME DOMAIN 著者 Dayie, K.T. 登録日 2005-12-02 公開日 2006-02-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of a self-splicing group II intron catalytic effector domain 5: parallels with spliceosomal U6 RNA Rna, 12, 2006
2F89	Crystal structure of human FPPS in complex with pamidronate 分子名称: Farnesyl Diphosphate Synthase, MANGANESE (II) ION, PAMIDRONATE, ... 著者 Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. 登録日 2005-12-02 公開日 2006-02-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
2F8A	Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 分子名称: Glutathione peroxidase 1, MALONIC ACID 著者 Kavanagh, K.L, Johansson, C, Smee, C, Gileadi, O, von Delft, F, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2005-12-02 公開日 2005-12-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 To be Published
2F8B	NMR structure of the C-terminal domain (dimer) of HPV45 oncoprotein E7 分子名称: Protein E7, ZINC ION 著者 Ohlenschlager, O, Gorlach, M. 登録日 2005-12-02 公開日 2006-08-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7. Oncogene, 25, 2006
2F8C	Crystal structure of FPPS in complex with Zoledronate 分子名称: Farnesyl Diphosphate Synthase, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. 登録日 2005-12-02 公開日 2006-02-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
2F8D	BenM effector-Binding domain crystallized from high pH conditions 分子名称: BENZOIC ACID, GLYCEROL, HTH-type transcriptional regulator benM, ... 著者 Ezezika, O.C, Haddad, S, Neidle, E.L, Momany, C. 登録日 2005-12-02 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Oligomerization of BenM, a LysR-type transcriptional regulator: structural basis for the aggregation of proteins in this family. Acta Crystallogr.,Sect.F, 63, 2007
2F8E	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein 分子名称: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-12-02 公開日 2006-03-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
2F8F	Crystal structure of the Y10F mutant of the gluathione s-transferase from schistosoma haematobium 分子名称: GLUTATHIONE, Glutathione S-transferase 28 kDa 著者 Gourlay, L.J, Baiocco, P, Angelucci, F, Miele, A.E, Bellelli, A, Brunori, M. 登録日 2005-12-02 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Probing the Mechanism of GSH Activation in Schistosoma haematobium Glutathione-S-transferase by Site-directed Mutagenesis and X-ray Crystallography. J.Mol.Biol., 360, 2006
2F8G	HIV-1 protease mutant I50V complexed with inhibitor TMC114 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ... 著者 Kovalevsky, A.Y, Weber, I.T. 登録日 2005-12-02 公開日 2006-03-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006
2F8H	Structure of acetylcitrulline deacetylase from Xanthomonas campestris in metal-free form 分子名称: aectylcitrulline deacetylase 著者 Shi, D, Yu, X, Roth, L, Allewell, N.M, Tuchman, M. 登録日 2005-12-02 公開日 2006-09-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of a novel N-acetyl-L-citrulline deacetylase from Xanthomonas campestris Biophys.Chem., 126, 2007
2F8I	Human transthyretin (TTR) complexed with Benzoxazole 分子名称: 2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID, Transthyretin 著者 Palaninathan, S.K, Mohamedmohaideen, N.N, Sacchettini, J.C, Kelly, J.W. 登録日 2005-12-02 公開日 2005-12-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.541 Å) 主引用文献 Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action Angew.Chem.Int.Ed.Engl., 42, 2003
2F8J	Crystal structure of Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transferase) (tm1040) from Thermotoga maritima at 2.40 A resolution 分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Histidinol-phosphate aminotransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2005-12-02 公開日 2006-02-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transferase) (tm1040) from Thermotoga maritima at 2.40 A resolution To be published
2F8K	Sequence specific recognition of RNA hairpins by the SAM domain of Vts1 分子名称: 5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1 著者 Aviv, T, Lin, Z, Ben-Ari, G, Smibert, C.A, Sicheri, F. 登録日 2005-12-02 公開日 2006-01-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p. Nat.Struct.Mol.Biol., 13, 2006
2F8L	Crystal structure of a putative class i s-adenosylmethionine-dependent methyltransferase (lmo1582) from listeria monocytogenes at 2.20 A resolution 分子名称: CHLORIDE ION, GLYCEROL, S-ADENOSYLMETHIONINE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2005-12-02 公開日 2006-01-17 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of (16411011) from Listeria monocytogenes LI2 at 2.20 A resolution To be published
2F8M	Ribose 5-phosphate isomerase from Plasmodium falciparum 分子名称: PHOSPHATE ION, ribose 5-phosphate isomerase 著者 Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-12-02 公開日 2005-12-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.087 Å) 主引用文献 Structure of ribose 5-phosphate isomerase from Plasmodium falciparum. Acta Crystallogr.,Sect.F, 62, 2006
2F8N	2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes 分子名称: Core histone macro-H2A.1, Histone 3, H2ba, ... 著者 Chakravarthy, S, Luger, K. 登録日 2005-12-02 公開日 2006-05-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Nucleosomes containing the histone domain of macroH2A: In vitro possibilities. To be Published

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