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2F6B
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Structural and active site modification studies implicate Glu, Trp and Arg in the activity of xylanase from alkalophilic Bacillus sp. (NCL 87-6-10).
分子名称: Family 11 Xylanase
著者Satyanarayana, L, Balakrishnan, H, Gaikward, S, Suresh, C.G.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and active site modification studies implicate Glu, Trp and Arg in the activity of xylanase from alkalophilic Bacillus sp. (NCL 87-6-10).
To be Published
2F6C
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Reaction geometry and thermostability of pyranose 2-oxidase from the white-rot fungus Peniophora sp., Thermostability mutant E542K
分子名称: DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase, ...
著者Bannwarth, M, Heckmann-Pohl, D.M, Bastian, S, Giffhorn, F, Schulz, G.E.
登録日2005-11-29
公開日2006-06-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Reaction Geometry and Thermostable Variant of Pyranose 2-Oxidase from the White-Rot Fungus Peniophora sp.
Biochemistry, 45, 2006
2F6D
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Structure of the complex of a glucoamylase from Saccharomycopsis fibuligera with acarbose
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Glucoamylase GLU1, PHOSPHATE ION, ...
著者Sevcik, J, Hostinova, E, Solovicova, A, Gasperik, J, Dauter, Z, Wilson, K.S.
登録日2005-11-29
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain.
Febs J., 273, 2006
2F6E
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Clostridium difficile Toxin A C-terminal fragment 1 (TcdA-f1)
分子名称: Toxin A
著者Ng, K.K, Ho, J.G.
登録日2005-11-29
公開日2005-12-20
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A
Proc.Natl.Acad.Sci.Usa, 102, 2005
2F6F
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The structure of the S295F mutant of human PTP1B
分子名称: CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein phosphatase, ...
著者Montalibet, J, Skorey, K, McKay, D, Scapin, G, Asante-Appiah, E, Kennedy, B.P.
登録日2005-11-29
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding.
J.Biol.Chem., 281, 2006
2F6G
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BenM effector binding domain
分子名称: CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION
著者Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C.
登録日2005-11-29
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator.
J.Mol.Biol., 367, 2007
2F6H
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Myosin V cargo binding domain
分子名称: Myosin-2
著者Pashkova, N, Jin, Y, Ramaswamy, S, Weisman, L.S.
登録日2005-11-29
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for myosin V discrimination between distinct cargoes
Embo J., 25, 2006
2F6I
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Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum
分子名称: ATP-dependent CLP protease, putative
著者Mulichak, A, Loppnau, P, Bray, J, Amani, M, Vedadi, M, Wasney, G, Finerty, P, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C, Hui, R, Plotnikova, O, Structural Genomics Consortium (SGC)
登録日2005-11-29
公開日2005-12-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
2F6J
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Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
分子名称: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
著者Li, H, Patel, D.J.
登録日2005-11-29
公開日2006-07-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2F6K
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Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LpR24
分子名称: MANGANESE (II) ION, metal-dependent hydrolase
著者Das, K, Xiao, R, Acton, T, Ma, L, Arnold, E, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2005-11-29
公開日2006-01-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of ACMDS from Lactobacillus plantarum
To be Published
2F6L
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X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis
分子名称: Chorismate mutase
著者Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E.
登録日2005-11-29
公開日2005-12-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
J.Bacteriol., 188, 2006
2F6M
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Structure of a Vps23-C:Vps28-N subcomplex
分子名称: DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
著者Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
登録日2005-11-29
公開日2006-04-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
2F6N
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Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the free form
分子名称: ZINC ION, bromodomain PHD finger transcription factor
著者Li, H, Patel, D.J.
登録日2005-11-29
公開日2006-07-11
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2F6P
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BenM effector binding domain- SeMet derivative
分子名称: ACETATE ION, HTH-type transcriptional regulator benM, SODIUM ION, ...
著者Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C.
登録日2005-11-29
公開日2006-10-31
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator.
J.Mol.Biol., 367, 2007
2F6Q
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The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisomal 3,2-trans-enoyl-CoA isomerase
著者Turnbull, A, Lukacik, P, Shafqat, N, Smee, C, Berridge, G, Guo, K, von Delft, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Gileadi, O, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2005-11-29
公開日2005-12-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)
To be Published
2F6R
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Crystal structure of Bifunctional coenzyme A synthase (CoA synthase): (18044849) from MUS MUSCULUS at 1.70 A resolution
分子名称: ACETYL COENZYME *A, Bifunctional coenzyme A synthase, UNKNOWN LIGAND
著者Joint Center for Structural Genomics (JCSG)
登録日2005-11-29
公開日2005-12-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Bifunctional coenzyme A synthase (CoA synthase) (18044849) from MUS MUSCULUS at 1.70 A resolution
To be published
2F6S
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Structure of cell filamentation protein (fic) from Helicobacter pylori
分子名称: PHOSPHATE ION, ZINC ION, cell filamentation protein, ...
著者Cuff, M.E, Xu, X, Zheng, H, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-11-29
公開日2006-01-10
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of cell filamentation protein (fic) from Helicobacter pylori
To be Published
2F6T
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: 3(S)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER, CHLORIDE ION, MAGNESIUM ION, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
2F6U
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Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with citrate
分子名称: (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase, CITRIC ACID
著者Payandeh, J.
登録日2005-11-29
公開日2006-01-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
J.Biol.Chem., 281, 2006
2F6V
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: (3R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER, CHLORIDE ION, MAGNESIUM ION, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
2F6W
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: (2-METHYL-5-PHENYL-2H-PYRAZOL-3-YL)-SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
2F6X
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Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with sn-G1P and MPD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase, SN-GLYCEROL-1-PHOSPHATE
著者Payandeh, J.M.
登録日2005-11-29
公開日2006-01-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
J.Biol.Chem., 281, 2006
2F6Y
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: 3(R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER, CHLORIDE ION, MAGNESIUM ION, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
2F6Z
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein phosphatase, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
2F70
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Protein tyrosine phosphatase 1B with sulfamic acid inhibitors
分子名称: (3-{[3-(3-SULFOAMINO-PHENYL)-PROPIONYLAMINO]-METHYL}-PHENYL)-SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Evdokimov, A.G, Pokross, M.E, Klopfenstein, S.R.
登録日2005-11-29
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Bioorg.Med.Chem.Lett., 16, 2006

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