PDB: 7770 件ウェブページステータス検索Chemie searchBIRD

---

6J29	The structure of HLA-A*3003/MTB 分子名称: Beta-2-microglobulin, HLA-A*3003, MTB 著者 Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. 登録日 2018-12-31 公開日 2019-09-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
7QJU	EED in complex with PRC2 allosteric inhibitor compound 7 分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... 著者 Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. 登録日 2021-12-17 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
7QJG	EED in complex with PRC2 allosteric inhibitor compound 6 分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-7-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... 著者 Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. 登録日 2021-12-16 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
7QK4	EED in complex with PRC2 allosteric inhibitor compound 22 (MAK683) 分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... 著者 Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. 登録日 2021-12-17 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
8FG4	HRAS R97L Crystal Form 1 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Fetics, S, Johnson, C.W, Mattos, C. 登録日 2022-12-12 公開日 2023-09-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8FVJ	Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5 分子名称: Core-binding factor subunit beta, Cullin-5, Elongin-B, ... 著者 Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. 登録日 2023-01-19 公開日 2023-09-06 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
5XW6	Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE 著者 Kasuya, G, Hattori, M, Nureki, O. 登録日 2017-06-29 公開日 2017-10-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel Nat Commun, 8, 2017
5XQ0	Structural basis of kindlin-mediated integrin recognition and activation 分子名称: Fermitin family homolog 2,Integrin beta-1, GLYCEROL 著者 Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. 登録日 2017-06-05 公開日 2017-07-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8FVI	Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 分子名称: Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... 著者 Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. 登録日 2023-01-19 公開日 2023-09-06 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
8FG3	HRAS R97L Crystal Form 2 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER 著者 Fetics, S, Johnson, C.W, Mattos, C. 登録日 2022-12-12 公開日 2023-09-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
6J6L	Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F 分子名称: ISOPROPYL ALCOHOL, Ryanodine receptor 2 著者 Ma, R, Lin, L, Yuchi, Z. 登録日 2019-01-15 公開日 2020-01-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.452 Å) 主引用文献 A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes. Sci Rep, 11, 2021
5Y2B	Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase 著者 Chen, W, Qu, M.B, Zhou, Y, Yang, Q. 登録日 2017-07-24 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
7QCD	CryoEM structure of the Smc5/6-holocomplex (composite structure) 分子名称: E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, ... 著者 Hallett, S.T, Oliver, A.W. 登録日 2021-11-23 公開日 2022-09-21 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-EM structure of the Smc5/6 holo-complex. Nucleic Acids Res., 50, 2022
5Y2C	Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2 E2180L mutant in complex with PENTA-N-ACETYLCHITOOCTAOSE (NAG)5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase 著者 Chen, W, Qu, M.B, Zhou, Y, Yang, Q. 登録日 2017-07-24 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
8FCI	tRNA (N1G37) Methyltransferase (TrmD) of Mycobacterium avium complexed with S-Adenosyl homocysteine 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase 著者 Lavallee, T, Mehta, K, Young, A, Cortes, J, Isaacson, B, Brylewski, J, Schlegel, F, Doti, L, Battaile, K, Stojanoff, V, Perez, A, Bolen, R. 登録日 2022-12-01 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 tRNA (N1G37) Methyltransferase (TrmD) of Mycobacterium avium complexed with S-Adenosyl homocysteine To Be Published
7QH0	Apo structure of the Leishmania mexicana triose-phosphate isomerase (LmTIM), N11A-E65Q variant, open conformation 分子名称: CHLORIDE ION, SODIUM ION, Triosephosphate isomerase 著者 Cordara, G, Wierenga, R.K. 登録日 2021-12-10 公開日 2022-10-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Role of Asn11 in Catalysis by Triosephosphate Isomerase. Biochemistry, 62, 2023
8FCH	Apo Structure of (N1G37) Methyltransferase from Mycobacterium avium 分子名称: tRNA (guanine-N(1)-)-methyltransferase 著者 Isaacson, B, Brylewski, J, Schlegel, F, Cortes, J, Lavallee, T, Mehta, K, Young, A, Doti, L, Battaile, K.P, Stojanoff, V, Perez, A, Bolen, R. 登録日 2022-12-01 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.956 Å) 主引用文献 Apo structure of (N1G37) Methyltransferase from Mycobacterium avium. To Be Published
6J1V	The structure of HLA-A*3003/RT313 分子名称: Beta-2-microglobulin, HLA-A*3003, RT313 著者 Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. 登録日 2018-12-29 公開日 2019-09-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
5XZC	Cryo-EM structure of p300-p53 protein complex 分子名称: Cellular tumor antigen p53, Histone acetyltransferase p300 著者 Ghosh, R, Roy, S, Sengupta, J. 登録日 2017-07-12 公開日 2019-01-23 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (10.7 Å) 主引用文献 Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300. Biochemistry, 2019
6HA9	Structure of an endo-Xyloglucanase from Cellvibrio japonicus complexed with XXXG(2F)-beta-DNP 分子名称: Cellulase, putative, cel5D, ... 著者 Offen, W.A, Davies, G.J. 登録日 2018-08-07 公開日 2018-10-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluoro-oligosaccharide inhibitor of endo-xyloglucanases. Org. Biomol. Chem., 16, 2018
6HTX	WT Hepatitis B core protein capsid 分子名称: Capsid protein 著者 Bottcher, B, Nassal, M. 登録日 2018-10-05 公開日 2018-12-26 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Structure of Mutant Hepatitis B Core Protein Capsids with Premature Secretion Phenotype. J. Mol. Biol., 430, 2018
7QB0	Solution structure of paxillin LIM2/3 分子名称: Isoform Alpha of Paxillin, ZINC ION 著者 Prestel, A, Michaelis, M, Klishin, N, Moeller, H.M. 登録日 2021-11-17 公開日 2022-11-30 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 A flexible loop in the paxillin LIM3 domain mediates direct binding to integrin beta3 To Be Published
5Y2A	Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2 分子名称: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase 著者 Chen, W, Qu, M.B, Zhou, Y, Yang, Q. 登録日 2017-07-24 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
6JDP	the imm52 family protein TsiT (PA3908) from Pseudomonas aeruginosa 分子名称: Imm52 family protein, PHOSPHATE ION, SODIUM ION 著者 She, Z. 登録日 2019-02-02 公開日 2019-03-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Structural characterization of the Imm52 family protein TsiT in Pseudomonas aeruginosa. Protein Sci., 28, 2019
6JD8	Structure of a proline specific mutant of human cathepsin L 分子名称: 1,2-ETHANEDIOL, Cathepsin L1, DI(HYDROXYETHYL)ETHER, ... 著者 Choudhury, D, Biswas, S. 登録日 2019-01-31 公開日 2020-02-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.457 Å) 主引用文献 Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity. Protein Eng.Des.Sel., 34, 2021

<139140141142143144145146147148149150151152153154>