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3FWO
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BU of 3fwo by Molmil
The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
分子名称: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA
著者Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A.
登録日2009-01-19
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, 2009
4DZN
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BU of 4dzn by Molmil
A de novo designed Coiled Coil CC-pIL
分子名称: COILED-COIL PEPTIDE CC-PIL
著者Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N.
登録日2012-03-01
公開日2012-08-29
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology.
ACS Synth Biol, 1, 2012
6OHZ
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BU of 6ohz by Molmil
Structure of an uncharacterized protein from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
分子名称: 1,2-ETHANEDIOL, Uncharacterized protein
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-04-08
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of an uncharacterized protein from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
to be published
8Z1I
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BU of 8z1i by Molmil
Crystal structure of the isomerase Art22 with ethylene glycol
分子名称: 1,2-ETHANEDIOL, Art22, MANGANESE (II) ION, ...
著者Guo, L, Li, P.W, Li, D.F, Chen, Y.H.
登録日2024-04-11
公開日2025-04-16
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of the isomerase Art22 with ethylene glycol
To Be Published
7P3P
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BU of 7p3p by Molmil
Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles
分子名称: Gag polyprotein
著者Wang, X, Nonin-Lecomte, S, Bouaziz, S.
登録日2021-07-08
公開日2023-01-18
最終更新日2024-03-27
実験手法SOLUTION NMR
主引用文献Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles
To Be Published
5YXO
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BU of 5yxo by Molmil
Crystal structure of shaft pilin spaD from Lactobacillus rhamnosus GG in bent conformation
分子名称: Pilus assembly protein
著者Chaurasia, P, Pratap, S, Palva, A, von Ossowski, I, Krishnan, V.
登録日2017-12-06
公開日2018-06-20
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Bent conformation of a backbone pilin N-terminal domain supports a three-stage pilus assembly mechanism.
Commun Biol, 1, 2018
9RF2
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BU of 9rf2 by Molmil
M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography: ELF5
分子名称: CHLORIDE ION, Monoacylglycerol lipase, [1-[6-[(4-methoxyphenyl)amino]pyrimidin-4-yl]pyrazol-4-yl]-[(3R)-3-oxidanylpyrrolidin-1-yl]methanone, ...
著者Riegler-Berket, L, Goedl, L, Oberer, M, Polidori, N.
登録日2025-06-04
公開日2025-08-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography
To Be Published
9OMU
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BU of 9omu by Molmil
Crystal structure of E. coli ApaH in complex with Ap4G
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-14
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9OMW
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BU of 9omw by Molmil
Crystal structure of E. coli ApaH in complex with Ap4U
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], GLYCEROL, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-14
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9OP2
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BU of 9op2 by Molmil
Crystal structure of E. coli ApaH in complex with Ap4GUAA
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-16
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9UO8
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BU of 9uo8 by Molmil
Crystal structure of Keap1 in complex with a small molecule inhibitor
分子名称: 4-ethoxy-~{N}-[4-[(4-ethoxyphenyl)sulfonylamino]-3-(2-oxidanylidene-2-pyrrol-1-yl-ethyl)naphthalen-1-yl]benzenesulfonamide, FORMIC ACID, Kelch-like ECH-associated protein 1
著者Ishida, H, Osawa, M.
登録日2025-04-25
公開日2025-09-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Development of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory Effects.
Chemmedchem, 2025
9OPH
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BU of 9oph by Molmil
Crystal structure of E. coli ApaH in complex with Up4AG
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-19
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9OON
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BU of 9oon by Molmil
Crystal structure of E. coli ApaH in complex with Ap4GU
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-16
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9NMR
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BU of 9nmr by Molmil
Structure of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ...
著者Weninger, G, Marks, A.R.
登録日2025-03-04
公開日2025-10-08
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural basis for statin-induced skeletal muscle weakness
To Be Published
9OPG
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BU of 9opg by Molmil
Crystal structure of E. coli ApaH in complex with Ap4UG
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ...
著者Nuthanakanti, A, Serganov, A.
登録日2025-05-19
公開日2025-09-03
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献ApaH decaps Np 4 N-capped RNAs in two alternative orientations.
Nat.Chem.Biol., 2025
9UDG
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BU of 9udg by Molmil
Cryo-EM structure of Na+-translocating NADH-ubiquinone oxidoreductase from Vibrio cholerae reduced by NADH, with bound aurachin D-42
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Aurachin D, CALCIUM ION, ...
著者Ishikawa-Fukuda, M, Kishikawa, J, Kato, T, Murai, M.
登録日2025-04-06
公開日2025-06-25
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献The Na + -pumping mechanism driven by redox reactions in the NADH-quinone oxidoreductase from Vibrio cholerae relies on dynamic conformational changes.
Biorxiv, 2025
9PLK
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BU of 9plk by Molmil
Interaction of human CYP3A4 with the drug darifenacin
分子名称: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Sevrioukova, I.F.
登録日2025-07-15
公開日2025-09-17
最終更新日2025-09-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Interaction of cytochrome P450 3A4 with cannabinoids and the drug darifenacin.
J.Biol.Chem., 2025
5MFM
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BU of 5mfm by Molmil
Designed armadillo repeat protein peptide fusion YIIIM6AII_GS11_(KR)5
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Importin subunit alpha, ...
著者Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A.
登録日2016-11-18
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Curvature of designed armadillo repeat proteins allows modular peptide binding.
J. Struct. Biol., 201, 2018
2G92
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BU of 2g92 by Molmil
Crystal Structure Analysis of the RNA Dodecamer CGC-(NF2)-AAUUAGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2)
分子名称: 5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*AP*GP*CP*G)-3'
著者Egli, M, Li, F.
登録日2006-03-04
公開日2006-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide.
Acs Chem.Biol., 1, 2006
8D7P
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BU of 8d7p by Molmil
Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide
分子名称: Casein kinase I isoform delta, Period circadian protein peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8ZNA
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BU of 8zna by Molmil
Myxococcus xanthus RomX
分子名称: 1,2-ETHANEDIOL, RomX
著者Chakraborty, S, Gayathri, P.
登録日2024-05-26
公開日2025-06-04
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity
To Be Published
5L9L
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BU of 5l9l by Molmil
Crystal structure of the PBP MotA from A. tumefaciens B6 in complex with glucopine
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucopine, ...
著者Marty, L, Morera, S.
登録日2016-06-10
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for High Specificity of Amadori Compound and Mannopine Opine Binding in Bacterial Pathogens.
J.Biol.Chem., 291, 2016
1TOB
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BU of 1tob by Molmil
SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES
分子名称: 1,3-DIAMINO-5,6-DIHYDROXYCYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ...
著者Jiang, L, Suri, A.K, Fiala, R, Patel, D.J.
登録日1996-12-12
公開日1997-06-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex.
Chem.Biol., 4, 1997
9NMO
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BU of 9nmo by Molmil
Structure of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
著者Weninger, G, Marks, A.R.
登録日2025-03-04
公開日2025-10-08
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis for statin-induced skeletal muscle weakness
To Be Published
9RCG
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BU of 9rcg by Molmil
Vitamin D receptor complex with a vitamin D receptor agonist/histone deacetylase inhibitor hybrid molecule
分子名称: 4-[4-[3-[5-[(3~{S})-4,4-dimethyl-3-oxidanyl-pentyl]-4-methyl-1,3-thiazol-2-yl]pentan-3-yl]phenoxy]-~{N}-oxidanyl-butanamide, Nuclear receptor coactivator 2, Vitamin D3 receptor A
著者Rochel, N.
登録日2025-05-28
公開日2025-10-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Hyperagonism of a Vitamin D Receptor Agonist/Histone Deacetylase Inhibitor Hybrid Molecule.
J.Med.Chem., 2025

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件を2025-10-15に公開中

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