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2F4U
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Asite RNA + designer antibiotic
分子名称: (2R)-4-AMINO-N-((1R,2S,3R,4R,5S)-5-AMINO-4-[(2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-{2-[(3-AMINOPROPYL)AMINO]ETHOXY}-3-HYDROXYCYCLOHEXYL)-2-HYDROXYBUTANAMIDE, 5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
著者Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S.
登録日2005-11-24
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol., 13, 2006
2F4V
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30S ribosome + designer antibiotic
分子名称: (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ...
著者Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S.
登録日2005-11-24
公開日2006-07-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
2F4W
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Human ubiquitin-conjugating enzyme E2 J2
分子名称: ubiquitin-conjugating enzyme E2, J2
著者Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-11-24
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2F4X
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NMR Solution of HIV-1 Lai Kissing Complex
分子名称: 5'-R(P*GP*GP*UP*UP*GP*CP*UP*GP*AP*AP*GP*CP*GP*CP*GP*CP*AP*CP*GP*GP*CP*AP*AP*C)-3'
著者Kieken, F, Paquet, F, Brule, F, Paoletti, J, Lancelot, G.
登録日2005-11-24
公開日2006-02-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A new NMR solution structure of the SL1 HIV-1Lai loop-loop dimer
Nucleic Acids Res., 34, 2006
2F4Y
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Barnase cross-linked with glutaraldehyde
分子名称: Ribonuclease, ZINC ION
著者Prange, T, Salem, M.
登録日2005-11-24
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations.
Biochim.Biophys.Acta, 1764, 2006
2F4Z
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Toxoplasma gondii ubiquitin conjugating enzyme TgTwinScan_2721- E2 domain
分子名称: GLYCEROL, TgTwinScan_2721 - E2 domain, UNKNOWN ATOM OR ION
著者Dong, A, Lew, J, Zhao, Y, Melone, M, Alam, Z, Kozieradski, I, Wasney, G, Vedadi, M, Sundstrom, M, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
登録日2005-11-24
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2F51
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Structure of Trichomonas vaginalis thioredoxin
分子名称: thioredoxin
著者Iulek, J, Alphey, M.S, Hunter, W.N.
登録日2005-11-25
公開日2006-01-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution structure of recombinant Trichomonas vaginalis thioredoxin.
Acta Crystallogr.,Sect.D, 62, 2006
2F52
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Solution structure of cold shock protein CspB from Bacillus subtilis in complex with heptathymidine
分子名称: Cold shock protein cspB
著者Zeeb, M, Sticht, H, Balbach, J.
登録日2005-11-25
公開日2006-09-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution.
Nucleic Acids Res., 34, 2006
2F53
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Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity
分子名称: Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ...
著者Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M.
登録日2005-11-25
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
2F54
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Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity
分子名称: Beta-2-microglobulin, Cancer/testis antigen 1B, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M.
登録日2005-11-25
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
2F55
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Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna
分子名称: 5'-D(P*(DU)P*(DU)P*(DU))-3', 5'-D(P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU))-3', SULFATE ION, ...
著者Lu, J.Z, Jordan, J.B, Sakon, J.
登録日2005-11-25
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus
J.Biol.Chem., 281, 2006
2F56
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Barnase cross-linked with glutaraldehyde soaked in 6M urea
分子名称: Ribonuclease, UREA, ZINC ION
著者Prange, T, Salem, M.
登録日2005-11-25
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.955 Å)
主引用文献On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations.
Biochim.Biophys.Acta, 1764, 2006
2F57
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Crystal Structure Of The Human P21-Activated Kinase 5
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE, Serine/threonine-protein kinase PAK 7
著者Eswaran, J, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Bray, J, Das, S, Savitsky, P, Smee, C, Burgess, N, Fedorov, O, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2005-11-25
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.
Structure, 15, 2007
2F58
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
分子名称: 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ...
著者Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
登録日1998-10-23
公開日1999-02-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2F59
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Lumazine synthase RibH1 from Brucella abortus (Gene BruAb1_0785, Swiss-Prot entry Q57DY1) complexed with inhibitor 5-Nitro-6-(D-Ribitylamino)-2,4(1H,3H) Pyrimidinedione
分子名称: 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase 1, CALCIUM ION
著者Klinke, S, Zylberman, V, Bonomi, H.R, Haase, I, Guimaraes, B.G, Braden, B.C, Bacher, A, Fischer, M, Goldbaum, F.A.
登録日2005-11-25
公開日2006-11-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
J.Mol.Biol., 373, 2007
2F5A
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CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5
分子名称: PROTEIN (ANTIBODY 2F5 (HEAVY CHAIN)), PROTEIN (ANTIBODY 2F5 (LIGHT CHAIN))
著者Bryson, S, Julien, J.P, Hynes, R.C, Pai, E.F.
登録日1999-04-08
公開日2003-07-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol., 83, 2009
2F5B
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CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5 IN COMPLEX WITH ITS GP41 EPITOPE
分子名称: PROTEIN (ANTIBODY 2F5 (HEAVY CHAIN)), PROTEIN (ANTIBODY 2F5 (LIGHT CHAIN)), PROTEIN (GP41 EPITOPE)
著者Bryson, S, Julien, J.P, Hynes, R.C, Pai, E.F.
登録日1999-04-09
公開日2003-07-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol., 83, 2009
2F5C
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Bacillus subtilis Manganese transport regulator (MNTR) bound to manganese, hexagonal crystal form
分子名称: MANGANESE (II) ION, SULFATE ION, Transcriptional regulator mntR
著者Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A.
登録日2005-11-25
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2F5D
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Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 6.5
分子名称: MANGANESE (II) ION, Transcriptional regulator mntR
著者Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A.
登録日2005-11-25
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2F5E
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Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AB conformation, pH 6.5
分子名称: MANGANESE (II) ION, Transcriptional regulator mntR
著者Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A.
登録日2005-11-25
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2F5F
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Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 8.5
分子名称: MANGANESE (II) ION, Transcriptional regulator mntR
著者Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A.
登録日2005-11-25
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
2F5G
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Crystal structure of IS200 transposase
分子名称: Transposase, putative
著者Lee, H.H, Yoon, J.Y, Kim, H.S, Kang, J.Y, Kim, K.H, Kim, D.J, Suh, S.W.
登録日2005-11-25
公開日2005-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a Metal Ion-bound IS200 Transposase
J.Biol.Chem., 281, 2006
2F5H
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Solution structure of the alpha-domain of human Metallothionein-3
分子名称: CADMIUM ION, Metallothionein-3
著者Wang, H, Zhang, Q, Cai, B, Li, H.Y, Sze, K.H, Huang, Z.X, Wu, H.M, Sun, H.Z.
登録日2005-11-25
公開日2006-05-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of human metallothionein-3 (MT-3)
Febs Lett., 580, 2006
2F5I
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X-ray structure of spermidine/spermine N1-acetyltransferase (SAT) from Homo sapiens
分子名称: Diamine acetyltransferase 1
著者Zhu, Y.Q, Zhu, D.Y, Vonrhein, C, Wang, D.C.
登録日2005-11-25
公開日2005-12-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human spermidine/spermine N1-acetyltransferase (hSSAT): the first structure of a new sequence family of transferase homologous superfamily
Proteins, 63, 2006
2F5J
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Crystal structure of MRG domain from human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006

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