2F4U

Asite RNA + designer antibiotic

Summary for 2F4U

• Entry DOI: 10.2210/pdb2f4u/pdb
• Related: 2F4S 2F4T 2F4V
• Descriptor: 5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R)-4-AMINO-N-((1R,2S,3R,4R,5S)-5-AMINO-4-[(2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-{2-[(3-AMINOPROPYL)AMINO]ETHOXY}-3-HYDROXYCYCLOHEXYL)-2-HYDROXYBUTANAMIDE (3 entities in total)
• Functional Keywords: asite rna, designer antibiotic, rna
• Total number of polymer chains: 2
• Total formula weight: 14010.76

Authors

Murray, J.B.,Meroueh, S.O.,Russell, R.J.,Lentzen, G.,Haddad, J.,Mobashery, S. (deposition date: 2005-11-24, release date: 2006-05-02, Last modification date: 2024-02-14)

• Primary citation: Murray, J.B.,Meroueh, S.O.,Russell, R.J.,Lentzen, G.,Haddad, J.,Mobashery, S.; Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site; Chem.Biol., 13:129-138, 2006; PubMed: 16492561; DOI: 10.1016/j.chembiol.2005.11.004

Experimental method

X-RAY DIFFRACTION (2.6 Å)