PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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7CVO	crystal structure of Arabidopsis CO CCT domain in complex with NF-YB3/YC4 and FT CORE2 DNA 分子名称: Chimera of Nuclear transcription factor Y subunit C-4 and Zinc finger protein CONSTANS, FT CORE2 DNA forward strand, FT CORE2 DNA reverse strand, ... 著者 Lv, X, Du, J. 登録日 2020-08-26 公開日 2021-06-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex. Plant Cell, 33, 2021
6B1C	Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a) 分子名称: 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one, Macrophage migration inhibitory factor, SULFATE ION 著者 Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. 登録日 2017-09-18 公開日 2018-01-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.163 Å) 主引用文献 Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. ACS Med Chem Lett, 8, 2017
6LH0	Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing apo-state 分子名称: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Transporter, sodium/bile acid symporter family 著者 Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. 登録日 2019-12-06 公開日 2020-12-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.812 Å) 主引用文献 Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
6L8F	Crystal structure of heterotetrameric complex of YoeB-YefM toxin-antitoxin from Staphylococcus aureus. 分子名称: Antitoxin, YoeB 著者 Yue, J, Xue, L. 登録日 2019-11-06 公開日 2020-09-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system. Nucleic Acids Res., 48, 2020
6LHE	Crystal Structure of Gold-bound NDM-1 分子名称: GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION 著者 Wang, H, Sun, H, Wang, M. 登録日 2019-12-07 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.206 Å) 主引用文献 Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nat Commun, 11, 2020
7D2C	The Crystal Structure of human PARP14 from Biortus. 分子名称: CHLORIDE ION, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP14 著者 Wang, F, Miao, Q, Lv, Z, Cheng, W, Lin, D, Xu, X, Tan, J. 登録日 2020-09-16 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 The Crystal Structure of human PARP14 from Biortus. To Be Published
6XA9	SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide 分子名称: GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
7D42	Structural basis of tropifexor as a potent and selective agonist for farnesoid X receptor 分子名称: Bile acid receptor, Peptide from Nuclear receptor coactivator 2, Tropifexor 著者 Jiang, L, Chen, Y. 登録日 2020-09-22 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor. Biochem.Biophys.Res.Commun., 534, 2021
6XTO	Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:NO complex 分子名称: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, COPPER (I) ION, ... 著者 Leisinger, F, Seebeck, F.P. 登録日 2020-01-16 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme Angew.Chem.Int.Ed.Engl., 2020
7D6H	Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant 分子名称: PHOSPHATE ION, Papain-like protease, ZINC ION 著者 Liu, J, Wang, Y, Pan, L. 登録日 2020-09-30 公開日 2020-11-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol, 28, 2021
7CYS	Crystal structure of barley agmatine coumaroyltransferase (HvACT), an N-acyltransferase in BAHD superfamily 分子名称: Agmatine coumaroyltransferase-1 著者 Yamane, M, Takenoya, M, Sue, M, Yajima, S. 登録日 2020-09-04 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of barley agmatine coumaroyltransferase, an N-acyltransferase from the BAHD superfamily. Acta Crystallogr.,Sect.F, 76, 2020
6XAA	SARS CoV-2 PLpro in complex with ubiquitin propargylamide 分子名称: Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
6XB2	Room temperature X-ray crystallography reveals catalytic cysteine in the SARS-CoV-2 3CL Mpro is highly reactive: Insights for enzyme mechanism and drug design 分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Kneller, D.W, Kovalevsky, A, Coates, L. 登録日 2020-06-05 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design. Iucrj, 7, 2020
6XB4	Structure of PrGV poxin in post-reactive state with Gp[2'-5']Ap[3'] 分子名称: 2',5'-GpAp, Poxin 著者 Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J. 登録日 2020-06-05 公開日 2020-11-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9, 2020
7CY1	Crystal Structure of MglC from Myxococcus xanthus 分子名称: Mutual gliding motility protein C, SODIUM ION 著者 Thakur, K.G, Kapoor, S, Kodesia, A. 登録日 2020-09-03 公開日 2021-01-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural characterization of Myxococcus xanthus MglC, a component of the polarity control system, and its interactions with its paralog MglB. J.Biol.Chem., 2021
7CYK	Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation 分子名称: MERCURY (II) ION, Transporter, sodium/bile acid symporter family 著者 Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. 登録日 2020-09-03 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.785 Å) 主引用文献 An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
7DHF	Vibrio vulnificus Wzb in complex with benzylphosphonate 分子名称: GLYCEROL, PHOSPHATE ION, Protein-tyrosine-phosphatase 著者 Ma, Q, Wang, X. 登録日 2020-11-14 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.211 Å) 主引用文献 Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
6LFA	Structure of the N-terminal domain of Wag31 分子名称: Cell wall synthesis protein Wag31, TRIETHYLENE GLYCOL 著者 Chaudhuri, B.N, Choukate, K. 登録日 2019-11-30 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of self-assembly in the lipid-binding domain of mycobacterial polar growth factor Wag31 Iucrj, 7, 2020
6XH0	Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.9 分子名称: MAGNESIUM ION, TAR binding protein 6.9, TRANS-ACTIVATION RESPONSE ELEMENT 著者 Chavali, S.S, Jenkins, J.L, Wedekind, J.E. 登録日 2020-06-18 公開日 2020-10-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. J.Biol.Chem., 295, 2020
6XHH	Far-red absorbing dark state of JSC1_58120g3 with bound 18-1, 18-2 dihydrobiliverdin IXa (DHBV), the native chromophore precursor 分子名称: 1,2-ETHANEDIOL, JSC1_58120g3, mesobiliverdin IX(alpha) 著者 Moreno, M.V, Rockwell, N.C, Fisher, A.J, Lagarias, J.C. 登録日 2020-06-18 公開日 2020-10-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A far-red cyanobacteriochrome lineage specific for verdins. Proc.Natl.Acad.Sci.USA, 117, 2020
4ZRB	Crystal Structure of Hypothetical Thioesterase Protein SP_1851 with Coenzyme A from Streptococcus pneumoniae TIGR4 分子名称: COENZYME A, Hypothetical Thioesterase Protein SP_1851 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2015-05-12 公開日 2015-05-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism. J.Biol.Chem., 291, 2016
6XI3	Crystal structure of tetra-tandem repeat in extending region of large adhesion protein 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Ye, Q, Vance, T.D.R, Davies, P.L. 登録日 2020-06-19 公開日 2020-10-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Essential role of calcium in extending RTX adhesins to their target. J Struct Biol X, 4, 2020
6KZU	Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: A novel stapled alpha-helical peptide modality 分子名称: 2JN-DAL-E03-DTY-2JN-DSG-TDF-DGL-MK8-DLE-DLE-2JN, E3 ubiquitin-protein ligase Mdm2 著者 Jiang, S, Brown, C.J. 登録日 2019-09-25 公開日 2019-10-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Macrocyclization of an all-d linear alpha-helical peptide imparts cellular permeability. Chem Sci, 11, 2020
6XRP	Crystal structure of GlpG in complex with peptide ketoamide inhibitor, Ac-RVWHA-ketoamide-phenylbutyl 分子名称: N-(4-phenylbutyl)formamide, Rhomboid protease GlpG, peptide ketoamide inhibitor 著者 Urban, S, Cho, S. 登録日 2020-07-13 公開日 2020-09-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020
7D52	Crystal structure of yak lactoperoxidase with a disordered propionic group of heme moiety at 2.20 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Singh, P.K, Rani, C, Ahmad, N, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. 登録日 2020-09-24 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Potassium-induced partial inhibition of lactoperoxidase: structure of the complex of lactoperoxidase with potassium ion at 2.20 angstrom resolution. J.Biol.Inorg.Chem., 26, 2021

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