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8QYI
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BU of 8qyi by Molmil
OleP in complex with lithocholic acid in high salt crystallization conditions
分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, Cytochrome P-450, FORMIC ACID, ...
著者Fata, F, Costanzo, A, Freda, I, Gugole, E, Bulfaro, G, Barbizzi, L, Di Renzo, M, Savino, C, Vallone, B, Montemiglio, L.C.
登録日2023-10-26
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献OleP in complex with lithocolic acid in high salt crystallization conditions
To Be Published
6ZPQ
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BU of 6zpq by Molmil
Crystal structure of the open conformation of Angiotensin-1 converting enzyme N-domain.
分子名称: 1,2-ETHANEDIOL, 2-METHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2020-07-09
公開日2020-10-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Angiotensin-converting enzyme open for business: structural insights into the subdomain dynamics.
Febs J., 288, 2021
2UVM
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BU of 2uvm by Molmil
Structure of PKBalpha PH domain in complex with a novel inositol headgroup surrogate, benzene 1,2,3,4-tetrakisphosphate
分子名称: BENZENE-1,2,3,4-TETRAYL TETRAKIS[DIHYDROGEN (PHOSPHATE)], RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE, SODIUM ION
著者Komander, D, Mills, S.J, Trusselle, M.N, Safrany, S.T, van Aalten, D.M.F, Potter, B.V.L.
登録日2007-03-12
公開日2007-04-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Novel Inositol Phospholipid Headgroup Surrogate Crystallised in the Pleckstrin Homology Domain of Protein Kinase Balpha.
Acs Chem.Biol., 2, 2007
5J2A
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BU of 5j2a by Molmil
Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
著者Batra, V.K, Wilson, S.H.
登録日2016-03-29
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2F
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BU of 5j2f by Molmil
Ternary complex crystal structure of DNA polymerase Beta with G:A mismatch at the primer terminus
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
著者Batra, V.K, Wilson, S.H.
登録日2016-03-29
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J6H
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BU of 5j6h by Molmil
Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
著者Berry, R, Rossjohn, J.
登録日2016-04-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016
5J8C
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BU of 5j8c by Molmil
Human MOF C316S, E350Q crystal structure
分子名称: CHLORIDE ION, Histone acetyltransferase KAT8, SODIUM ION, ...
著者McCullough, C.E, Marmorstein, R.
登録日2016-04-07
公開日2016-07-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.
J.Biol.Chem., 291, 2016
7C1X
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BU of 7c1x by Molmil
Unliganded structure of Pseudouridine kinase (PUKI) from Arabidopsis thaliana
分子名称: PfkB-like carbohydrate kinase family protein, SODIUM ION
著者Kim, S.H, Rhee, S.
登録日2020-05-06
公開日2020-11-18
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2.38942838 Å)
主引用文献Structural basis for the substrate specificity and catalytic features of pseudouridine kinase from Arabidopsis thaliana.
Nucleic Acids Res., 49, 2021
5JGL
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BU of 5jgl by Molmil
Crystal structure of GtmA in complex with S-Adenosylmethionine
分子名称: S-ADENOSYLMETHIONINE, SODIUM ION, UbiE/COQ5 family methyltransferase, ...
著者Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Doyle, S.
登録日2016-04-20
公開日2017-03-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7, 2017
7C1Y
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BU of 7c1y by Molmil
Pseudouridine and ADP bound structure of Pseudouridine kinase (PUKI) from Arabidopsis thaliana
分子名称: 5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione, ADENOSINE-5'-DIPHOSPHATE, PfkB-like carbohydrate kinase family protein, ...
著者Kim, S.H, Rhee, S.
登録日2020-05-06
公開日2020-11-18
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2.083426 Å)
主引用文献Structural basis for the substrate specificity and catalytic features of pseudouridine kinase from Arabidopsis thaliana.
Nucleic Acids Res., 49, 2021
4EIE
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BU of 4eie by Molmil
Crystal structure of cytochrome c6C from Synechococcus sp. PCC 7002
分子名称: CHLORIDE ION, Cytochrome c6, HEME C, ...
著者Krzywda, S, Bialek, W, Zatwarnicki, P, Jaskolski, M, Szczepaniak, A.
登録日2012-04-05
公開日2013-04-10
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Cytochrome c6 and c6C from Synechococcus sp. PCC 7002 - structure and function.
To be Published
4GU1
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BU of 4gu1 by Molmil
Crystal structure of LSD2
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.939 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
2X7A
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BU of 2x7a by Molmil
Structural basis of HIV-1 tethering to membranes by the Bst2-tetherin ectodomain
分子名称: BONE MARROW STROMAL ANTIGEN 2, CHLORIDE ION, GLYCEROL, ...
著者Natrajan, G, McCarthy, A.A, Weissenhorn, W.
登録日2010-02-25
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural Basis of HIV-1 Tethering to Membranes by the Bst-2/Tetherin Ectodomain.
Cell Host Microbe, 7, 2010
4HES
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BU of 4hes by Molmil
Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula.
分子名称: Beta-lactamase class A-like protein, FORMIC ACID, GLYCEROL, ...
著者Cuff, M.E, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-10-04
公開日2012-10-17
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula.
TO BE PUBLISHED
8SFS
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BU of 8sfs by Molmil
High Affinity nanobodies against GFP
分子名称: AMMONIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Ketaren, N.E, Rout, M.P, Bonnano, J.B, Almo, S.C.
登録日2023-04-11
公開日2024-05-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献High Affinity nanobodies against GFP
To Be Published
8SI2
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BU of 8si2 by Molmil
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in apo state
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, CHOLESTEROL, ...
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2023-04-14
公開日2023-05-17
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (2.19 Å)
主引用文献Structural mechanisms of TRPM7 activation and inhibition.
Nat Commun, 14, 2023
7BYF
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BU of 7byf by Molmil
The crystal structure of mouse ORF10-Rae1-Nup98 complex
分子名称: 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ...
著者Gao, P, Feng, H.
登録日2020-04-22
公開日2021-03-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.
Proc.Natl.Acad.Sci.USA, 117, 2020
2WMZ
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BU of 2wmz by Molmil
Structure of a mutated TolC
分子名称: CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC, SODIUM ION, ...
著者Hinchliffe, P, Pei, X.Y, Symmons, M.F, Koronakis, E, Hughes, C, Koronakis, V.
登録日2009-07-03
公開日2011-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Sequential Open States in a Symmetrical Opening Transition of the Tolc Exit Duct.
Proc.Natl.Acad.Sci.USA, 108, 2011
4CBC
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BU of 4cbc by Molmil
Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak
分子名称: HEGA-10, ION TRANSPORT PROTEIN, SODIUM ION
著者Bagneris, C, Naylor, C.E, Wallace, B.A.
登録日2013-10-12
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.664 Å)
主引用文献Prokaryotic Navms Channel as a Structural and Functional Model for Eukaryotic Sodium Channel Antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
2WWG
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BU of 2wwg by Molmil
Plasmodium falciparum thymidylate kinase in complex with dGMP and ADP
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Whittingham, J.L, Carrero-Lerida, J, Brannigan, J.A, Ruiz-Perez, L.M, Silva, A.P, Fogg, M.J, Wilkinson, A.J, Gilbert, I.H, Wilson, K.S, Gonzalez-Pacanowska, D.
登録日2009-10-23
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Efficient Phosphorylation of Aztmp and Dgmp by Plasmodium Falciparum Type I Thymidylate Kinase.
Biochem.J., 428, 2010
5JUI
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BU of 5jui by Molmil
domain-swapped dimer of the the KRT10-binding region (BR) of PsrP
分子名称: Cell wall surface anchor family protein, GLYCEROL, SODIUM ION
著者Schulte, T, Mikaelsson, C, Achour, A.
登録日2016-05-10
公開日2017-03-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.
Sci Rep, 6, 2016
3BGA
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BU of 3bga by Molmil
Crystal structure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482
分子名称: Beta-galactosidase, CHLORIDE ION, MAGNESIUM ION, ...
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-11-26
公開日2007-12-11
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure analysis of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482.
To be Published
5HXI
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BU of 5hxi by Molmil
2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5HN bound
分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxypyridine-3-carboxylic acid, BETA-MERCAPTOETHANOL, ...
著者Kobayashi, J, Mikami, B.
登録日2016-01-30
公開日2016-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Role of the Tyr270 residue in 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti
J. Biosci. Bioeng., 123, 2017
8P9Y
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BU of 8p9y by Molmil
SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
著者Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L.
登録日2023-06-06
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J.Med.Chem., 66, 2023
8PEJ
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BU of 8pej by Molmil
CjGH35 with a Galactosidase Activity-Based Probe
分子名称: (1~{S},2~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, Beta-galactosidase, ...
著者Offen, W.A, Davies, G.J.
登録日2023-06-14
公開日2023-10-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The development of a broad-spectrum retaining beta-exo-galactosidase activity-based probe.
Org.Biomol.Chem., 21, 2023

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