2X7A
Structural basis of HIV-1 tethering to membranes by the Bst2-tetherin ectodomain
Summary for 2X7A
Entry DOI | 10.2210/pdb2x7a/pdb |
Descriptor | BONE MARROW STROMAL ANTIGEN 2, SODIUM ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | tetherin, gpi-anchor, antiviral defense, b-cell activation, immune system, signal-anchor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Golgi apparatus, trans-Golgi network: Q10589 |
Total number of polymer chains | 11 |
Total formula weight | 76364.50 |
Authors | Natrajan, G.,McCarthy, A.A.,Weissenhorn, W. (deposition date: 2010-02-25, release date: 2010-04-28, Last modification date: 2011-07-13) |
Primary citation | Hinz, A.,Miguet, N.,Natrajan, G.,Usami, Y.,Yamanaka, H.,Renesto, P.,Hartlieb, B.,Mccarthy, A.A.,Simorre, J.P.,Gottlinger, H.,Weissenhorn, W. Structural Basis of HIV-1 Tethering to Membranes by the Bst-2/Tetherin Ectodomain. Cell Host Microbe, 7:314-, 2010 Cited by PubMed: 20399176DOI: 10.1016/J.CHOM.2010.03.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.77 Å) |
Structure validation
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