2X7A

Structural basis of HIV-1 tethering to membranes by the Bst2-tetherin ectodomain

Summary for 2X7A

Entry DOI	10.2210/pdb2x7a/pdb
Descriptor	BONE MARROW STROMAL ANTIGEN 2, SODIUM ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	tetherin, gpi-anchor, antiviral defense, b-cell activation, immune system, signal-anchor
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Golgi apparatus, trans-Golgi network: Q10589
Total number of polymer chains	11
Total formula weight	76364.50
Authors	Natrajan, G.,McCarthy, A.A.,Weissenhorn, W. (deposition date: 2010-02-25, release date: 2010-04-28, Last modification date: 2011-07-13)
Primary citation	Hinz, A.,Miguet, N.,Natrajan, G.,Usami, Y.,Yamanaka, H.,Renesto, P.,Hartlieb, B.,Mccarthy, A.A.,Simorre, J.P.,Gottlinger, H.,Weissenhorn, W. Structural Basis of HIV-1 Tethering to Membranes by the Bst-2/Tetherin Ectodomain. Cell Host Microbe, 7:314-, 2010 Cited by PubMed: 20399176 DOI: 10.1016/J.CHOM.2010.03.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation