PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4NS5	Crystal structure of human BS69 Bromo-Zinc finger-PWWP 分子名称: ZINC ION, Zinc finger MYND domain-containing protein 11 著者 Wang, J.C, Qin, S, Li, F.D, Li, S, Zhang, W, Wu, J.H, Shi, Y.Y. 登録日 2013-11-28 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding. Cell Res., 24, 2014
6UR9	DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template, dideoxy primer, 3'-amino-ddGTP (nGTP), and Ca2+ 分子名称: 3'-amino-2',3'-dideoxyguanosine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*CP*AP*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... 著者 Zhang, W, Lelyveld, V.S, Szostak, J.W. 登録日 2019-10-22 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
6US5	DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template, 3'-amino primer, dGpNHpp analog, and Mn2+ 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*(C42))-3'), ... 著者 Zhang, W, Lelyveld, V.S, Szostak, J.W. 登録日 2019-10-24 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
8ONQ	Structure of the amyloid-forming peptide Ac-EFIAWL from human GLP-1 分子名称: Peptide Ac-EFIAWL from hGLP-1 著者 Durvanger, Z. 登録日 2023-04-03 公開日 2023-08-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
4NHX	Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with N-oxalylglycine (NOG) 分子名称: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Horita, S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
6PZ3	Polymerase Eta-catalyzed insertion of correct G opposite template cytarabine (AraC) residue 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA Primer strand, DNA polymerase eta, ... 著者 Rechkoblit, O, Aggarwal, A.K. 登録日 2019-07-31 公開日 2019-11-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.395 Å) 主引用文献 Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase eta. Sci Rep, 9, 2019
6Q8A	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine 分子名称: 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
5ZB9	Crystal structure of Rtt109 from Aspergillus fumigatus 分子名称: DNA damage response protein Rtt109, putative, GLYCEROL 著者 Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. 登録日 2018-02-10 公開日 2018-07-25 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109. Cell, 174, 2018
6N2H	Structure of D-ornithine/D-lysine decarboxylase from Salmonella typhimurium 分子名称: 1,4-DIETHYLENE DIOXIDE, D-ornithine/D-lysine decarboxylase, DIMETHYL SULFOXIDE 著者 Phillips, R.S, Hoover, T.R. 登録日 2018-11-13 公開日 2019-10-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal Structure of d-Ornithine/d-Lysine Decarboxylase, a Stereoinverting Decarboxylase: Implications for Substrate Specificity and Stereospecificity of Fold III Decarboxylases. Biochemistry, 58, 2019
6Q89	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Leucyl)-Sulfamoyl)Adenosine 分子名称: 1,2-ETHANEDIOL, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
4NHM	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: GLYCEROL, MANGANESE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ... 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
6MYW	Gluconobacter Ene-Reductase (GluER) mutant - T36A 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Garfinkle, S.E, Jeffrey, P, Hyster, T.K. 登録日 2018-11-02 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.157 Å) 主引用文献 Photoexcitation of flavoenzymes enables a stereoselective radical cyclization. Science, 364, 2019
3UV2	Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit BPTF 分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, bromodomain of human nucleosome-remodeling factor subunit BPTF 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
6Q8C	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Uridine 分子名称: 1,2-ETHANEDIOL, 5'-O-(N-(L-Leucyl)-Sulfamoyl)Uridine, Leucine--tRNA ligase, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
4NHK	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA) 分子名称: GLYCEROL, MANGANESE (II) ION, PKHD-type hydroxylase TPA1, ... 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
5J70	The Chd1 DNA-binding domain in complex with 17mer DNA duplex 分子名称: Chromo domain-containing protein 1, DNA (5'-D(*CP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*G)-3') 著者 Bowman, G.D, Jenkins, K.R, Hauk, G. 登録日 2016-04-05 公開日 2017-06-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.956 Å) 主引用文献 Chd1 domains communicate across the DNA gyres of the nucleosome To Be Published
4NFL	Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor NPB-T 分子名称: 1-{2-deoxy-3,5-O-[(4-nitrophenyl)(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'(3')-deoxyribonucleotidase, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2013-10-31 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.375 Å) 主引用文献 Conformationally constrained nucleoside phosphonic acids - potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases. Org.Biomol.Chem., 12, 2014
4NHY	Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA) 分子名称: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Horita, S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
7E28	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium 分子名称: Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S. 登録日 2021-02-05 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
6Q8B	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)N3-methyluridine 分子名称: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
6O08	Gluconobacter Ene-Reductase (GluER) 分子名称: ACETATE ION, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... 著者 Garfinkle, S.E, Jeffrey, P, Hyster, T.K. 登録日 2019-02-15 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Photoexcitation of flavoenzymes enables a stereoselective radical cyclization. Science, 364, 2019
4NHL	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-oxalylglycine (NOG) 分子名称: MANGANESE (II) ION, N-OXALYLGLYCINE, PKHD-type hydroxylase TPA1 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
3REK	2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin 分子名称: DNA (146-MER), Histone H2A type1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
3REJ	2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) 分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
3REL	2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride 分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011

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