PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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3NFR	Casimiroin analog inhibitor of quinone reductase 2 分子名称: 6,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Sturdy, M, Mesecar, A.D, Jermihov, K, Cushman, M, Maiti, A. 登録日 2010-06-10 公開日 2012-01-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2 To be Published
6L8H	Crystal structure of CYP97C1 分子名称: Carotene epsilon-monooxygenase, chloroplastic, GLYCEROL, ... 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
3FWY	Crystal structure of the L protein of Rhodobacter sphaeroides light-independent protochlorophyllide reductase (BchL) with MgADP bound: a homologue of the nitrogenase Fe protein 分子名称: ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, ... 著者 Sarma, R, Barney, B.M, Hamilton, T.L, Jones, A, Seefeldt, L.C, Peters, J.W. 登録日 2009-01-19 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal Structure of the L Protein of Rhodobacter sphaeroides Light-Independent Protochlorophyllide Reductase with MgADP Bound: A Homologue of the Nitrogenase Fe Protein. Biochemistry, 47, 2008
3FW1	Quinone Reductase 2 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Winger, J.A, Hantschel, O, Superti-Furga, G, Kuriyan, J. 登録日 2009-01-16 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2). Bmc Struct.Biol., 9, 2009
3NC5	CYP134A1 structure with an open substrate binding loop 分子名称: Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ... 著者 Cryle, M.J, Schlichting, I. 登録日 2010-06-04 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
1D6U	CRYSTAL STRUCTURE OF E. COLI AMINE OXIDASE ANAEROBICALLY REDUCED WITH BETA-PHENYLETHYLAMINE 分子名称: 2-PHENYLETHYLAMINE, CALCIUM ION, COPPER (II) ION, ... 著者 Wilmot, C.M, Hajdu, J, McPherson, M.J, Knowles, P.F, Phillips, S.E.V. 登録日 1999-10-15 公開日 2000-02-02 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Visualization of dioxygen bound to copper during enzyme catalysis. Science, 286, 1999
2IWK	Inhibitor-bound form of nitrous oxide reductase from Achromobacter Cycloclastes at 1.7 Angstrom resolution 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ... 著者 Paraskevopoulos, K, Antonyuk, S.V, Sawers, R.G, Eady, R.R, Hasnain, S.S. 登録日 2006-06-30 公開日 2006-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insight Into Catalysis of Nitrous Oxide Reductase from High-Resolution Structures of Resting and Inhibitor-Bound Enzyme from Achromobacter Cycloclastes. J.Mol.Biol., 362, 2006
1LPS	A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES 分子名称: (1S)-MENTHYL HEXYL PHOSPHONATE GROUP, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Grochulski, P.G, Cygler, M.C. 登録日 1995-01-05 公開日 1995-02-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 A Structural Basis for the Chiral Preferences of Lipases J.Am.Chem.Soc., 116, 1994
3PER	Crystal Structure of BoxB with phosphate bound to the diiron center 分子名称: Benzoyl-CoA oxygenase component B, FE (III) ION, GLYCEROL, ... 著者 Weinert, T, Rather, L.J, Fuchs, G, Ermler, U. 登録日 2010-10-27 公開日 2011-06-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB. J.Biol.Chem., 286, 2011
5RB1	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001700a 分子名称: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
2XLU	Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: complex with thioNADP 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Orru, R, Fraaije, M.W, Mattevi, A. 登録日 2010-07-21 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Joint-Functions of Protein Residues and Nadp(H) in Oxygen-Activation by Flavin-Containing Monooxygenase J.Biol.Chem., 285, 2010
2XLS	Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: Asn78Lys mutant 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Orru, R, Fraaije, M.W, Mattevi, A. 登録日 2010-07-21 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Joint-Functions of Protein Residues and Nadp(H) in Oxygen-Activation by Flavin-Containing Monooxygenase J.Biol.Chem., 285, 2010
2Y33	S-nitrosylated PHD2 (GSNO soaked) in complex with Zn(II) and UN9 分子名称: EGL NINE HOMOLOG 1, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ZINC ION 著者 Chowdhury, R, Clifton, I.J, Schofield, C.J. 登録日 2010-12-18 公開日 2010-12-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (Egln1) J.Mol.Biol., 410, 2011
4PFD	Crystal structure of M. tuberculosis in complex with a cBT - non-covalent adduct 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, Probable decaprenylphosphoryl-beta-D-ribose oxidase, ... 著者 Neres, J, Panda, M, Cole, S. 登録日 2014-04-28 公開日 2015-10-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of M. tuberculosis in complex with a cBT To be published
6I3J	Bilirubin oxidase from Myrothecium verrucaria in complex with ferricyanide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bilirubin oxidase, CHLORIDE ION, ... 著者 Svecova, L, Koval, T, Skalova, T, Kolenko, P, Duskova, J, Ostergaard, L.H, Dohnalek, J. 登録日 2018-11-06 公開日 2019-10-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Trp-His covalent adduct in bilirubin oxidase is crucial for effective bilirubin binding but has a minor role in electron transfer. Sci Rep, 9, 2019
4BUR	Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD 分子名称: APOPTOSIS INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Martinez-Julvez, M, Herguedas, B, Hermoso, J.A, Ferreira, P, Villanueva, R, Medina, M. 登録日 2013-06-23 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53, 2014
1FEA	UNLIGANDED CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT 2.2 ANGSTROM RESOLUTION 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE 著者 Strickland, C, Karplus, P. 登録日 1995-07-12 公開日 1997-01-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crithidia Fasciculata Trypanothione Reductase at 1.70 A Resolution To be Published
5EQB	Crystal structure of lanosterol 14-alpha demethylase with intact transmembrane domain bound to itraconazole 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Monk, B.C, Tomasiak, T.M, Keniya, M.V, Huschmann, F.U, Tyndall, J.D.A, O'Connell III, J.D, Cannon, R.D, Finer-Morre, J, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) 登録日 2015-11-12 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc.Natl.Acad.Sci.USA, 111, 2014
3EBD	Structure of inhibited murine iNOS oxygenase domain 分子名称: (2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... 著者 Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. 登録日 2008-08-27 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
2FZM	Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with SO2 分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Tanner, J.J. 登録日 2006-02-09 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Redox-induced changes in flavin structure and roles of flavin N(5) and the ribityl 2'-OH group in regulating PutA--membrane binding. Biochemistry, 46, 2007
3EAI	Structure of inhibited murine iNOS oxygenase domain 分子名称: 4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... 著者 Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. 登録日 2008-08-25 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
1Y8J	Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor 分子名称: 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Sahli, S, Frank, B, Schweizer, W.B, Diederich, F, Blum-Kaelin, D, Aebi, J.D, Bohm, H.J, Oefner, C, Dale, G.E. 登録日 2004-12-13 公開日 2005-06-07 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-ray Crystal Structure Analysis HELV.CHIM.ACTA, 88, 2005
1N60	Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Cyanide-inactivated Form 分子名称: Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, Carbon monoxide dehydrogenase small chain, ... 著者 Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. 登録日 2002-11-08 公開日 2002-12-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
4NHL	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-oxalylglycine (NOG) 分子名称: MANGANESE (II) ION, N-OXALYLGLYCINE, PKHD-type hydroxylase TPA1 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
4A79	Crystal structure of human monoamine oxidase B (MAO B) in complex with pioglitazone 分子名称: (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE 著者 Binda, C, Aldeco, M, Geldenhuys, W.J, Tortorici, M, Mattevi, A, Edmondson, D.E. 登録日 2011-11-11 公開日 2012-04-25 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Molecular Insights Into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs Acs Med. Chem. Lett., 3, 2012

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