3NFR

Casimiroin analog inhibitor of quinone reductase 2

Summary for 3NFR

• Entry DOI: 10.2210/pdb3nfr/pdb
• Related: 3G5M 3GAM
• Descriptor: Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, 6,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one, ... (5 entities in total)
• Functional Keywords: nq02, quinone reductase 2, qr2, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P16083
• Total number of polymer chains: 2
• Total formula weight: 53867.12

Authors

Sturdy, M.,Mesecar, A.D.,Jermihov, K.,Cushman, M.,Maiti, A. (deposition date: 2010-06-10, release date: 2012-01-11, Last modification date: 2024-02-21)

• Primary citation: Sturdy, M.,Maiti, A.,Jermihov, K.,Cushman, M.,Mesecar, A.D.; X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2; To be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)