8J3N
 
 | |
8JYZ
 | | Cryo-EM structure of RCD-1 pore from Neurospora crassa | | 分子名称: | Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2 | | 著者 | Hou, Y.J, Sun, Q, Li, Y, Ding, J. | | 登録日 | 2023-07-04 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
|
|
8JYW
 | |
8JYX
 | |
6RR1
 | | Structure of 10% reduced KpDyP | | 分子名称: | GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... | | 著者 | Pfanzagl, V, Beale, J, Hofbauer, S. | | 登録日 | 2019-05-16 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner.
J.Biol.Chem., 295, 2020
|
|
7BKD
 | | Formate dehydrogenase - heterodisulfide reductase - formylmethanofuran dehydrogenase complex from Methanospirillum hungatei (heterodislfide reductase core and mobile arm in conformational state 1, composite structure) | | 分子名称: | CoB--CoM heterodisulfide reductase iron-sulfur subunit A, CoB--CoM heterodisulfide reductase subunit B, CoB--CoM heterodisulfide reductase subunit C, ... | | 著者 | Pfeil-Gardiner, O, Watanabe, T, Shima, S, Murphy, B.J. | | 登録日 | 2021-01-15 | | 公開日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Science, 373, 2021
|
|
7BKE
 | | Formate dehydrogenase - heterodisulfide reductase - formylmethanofuran dehydrogenase complex from Methanospirillum hungatei (heterodisulfide reductase core and mobile arm in conformational state 2, composite structure) | | 分子名称: | CoB--CoM heterodisulfide reductase iron-sulfur subunit A, CoB--CoM heterodisulfide reductase subunit B, CoB--CoM heterodisulfide reductase subunit C, ... | | 著者 | Pfeil-Gardiner, O, Watanabe, T, Shima, S, Murphy, B.J. | | 登録日 | 2021-01-15 | | 公開日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Science, 373, 2021
|
|
7BKB
 | | Formate dehydrogenase - heterodisulfide reductase - formylmethanofuran dehydrogenase complex from Methanospirillum hungatei (hexameric, composite structure) | | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CoB--CoM heterodisulfide reductase iron-sulfur subunit A, CoB--CoM heterodisulfide reductase subunit B, ... | | 著者 | Pfeil-Gardiner, O, Watanabe, T, Shima, S, Murphy, B.J. | | 登録日 | 2021-01-15 | | 公開日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Science, 373, 2021
|
|
5DU3
 | | Active form of human C1-inhibitor | | 分子名称: | Plasma protease C1 inhibitor | | 著者 | Pannu, N.S, Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A. | | 登録日 | 2015-09-18 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
|
|
7BKC
 | | Formate dehydrogenase - heterodisulfide reductase - formylmethanofuran dehydrogenase complex from Methanospirillum hungatei (dimeric, composite structure) | | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CoB--CoM heterodisulfide reductase iron-sulfur subunit A, CoB--CoM heterodisulfide reductase subunit B, ... | | 著者 | Pfeil-Gardiner, O, Watanabe, T, Shima, S, Murphy, B.J. | | 登録日 | 2021-01-15 | | 公開日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Science, 373, 2021
|
|
4ZU4
 | | X-ray structure of the 3,4-ketoisomerase domain of FdtD from Shewanella denitrificans | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | | 著者 | Thoden, J.B, Vinogradov, E, Gilbert, M, Salinger, A.J, Holden, H.M. | | 登録日 | 2015-05-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry.
Biochemistry, 54, 2015
|
|
5ABN
 | | CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPi. MUTATED RESIDUES D69S, T70D, S86E, D146T, Q202L, H232E, Q239R AND S301K. | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Medrano, F.J, Romero, A. | | 登録日 | 2015-08-07 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Improving the Ph-Stability of Versatile Peroxidase by Comparative Structural Analysis with a Naturally-Stable Manganese Peroxidase.
Plos One, 10, 2015
|
|
4ZWN
 | | Crystal Structure of a Soluble Variant of the Monoglyceride Lipase from Saccharomyces Cerevisiae | | 分子名称: | Monoglyceride lipase, NITRATE ION, SODIUM ION, ... | | 著者 | Aschauer, P, Rengachari, S, Gruber, K, Oberer, M. | | 登録日 | 2015-05-19 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | | 主引用文献 | Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim.Biophys.Acta, 1861, 2016
|
|
5ABO
 | | CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPi-br. MUTATED RESIDUES T2K, D69S, T70D, S86E, A131K, D146T, Q202L, Q219K, H232E, Q239R, L288R, S301K, A308R, A309K AND A314R. | | 分子名称: | CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, VERSATILE PEROXIDASE VPL2 | | 著者 | Medrano, F.J, Romero, A. | | 登録日 | 2015-08-07 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.095 Å) | | 主引用文献 | Improving the Ph-Stability of Versatile Peroxidase by Comparative Structural Analysis with a Naturally-Stable Manganese Peroxidase.
Plos One, 10, 2015
|
|
5A4K
 | | Crystal structure of the R139W variant of human NAD(P)H:quinone oxidoreductase | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Lienhart, W.D, Strandback, E, Gudipati, V, Uhl, M.K, Rantase, D.M, Zangger, K, Gruber, K, Macheroux, P. | | 登録日 | 2015-06-10 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
FEBS J., 284, 2017
|
|
8JJS
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2023-05-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
J.Am.Chem.Soc., 145, 2023
|
|
6RR6
 | | Structure of 100% reduced KpDyP | | 分子名称: | GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... | | 著者 | Pfanzagl, V, Beale, J, Hofbauer, S. | | 登録日 | 2019-05-17 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner.
J.Biol.Chem., 295, 2020
|
|
6RQY
 | | Structure of % reduced KpDyP | | 分子名称: | GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... | | 著者 | Pfanzagl, V, Beale, J, Hofbauer, S. | | 登録日 | 2019-05-16 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray-induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner.
J.Biol.Chem., 295, 2020
|
|
5ONP
 | |
6TP8
 | |
8OYU
 | | Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ... | | 著者 | Weckener, M, Naismith, J.H, Owens, R.J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
|
|
5D6B
 | | Human fumarase (wild type) | | 分子名称: | Fumarate hydratase, mitochondrial | | 著者 | Pereira de Padua, R.A, Nonato, M.C. | | 登録日 | 2015-08-11 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase.
Acta Crystallogr F Struct Biol Commun, 70, 2014
|
|
8PE9
 | | Complex between DDR1 DS-like domain and PRTH-101 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N. | | 登録日 | 2023-06-13 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.152 Å) | | 主引用文献 | A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer, 11, 2023
|
|
1DDJ
 | | CRYSTAL STRUCTURE OF HUMAN PLASMINOGEN CATALYTIC DOMAIN | | 分子名称: | PLASMINOGEN | | 著者 | Wang, X, Terzyan, S, Tang, J, Loy, J, Lin, X, Zhang, X. | | 登録日 | 1999-11-10 | | 公開日 | 2000-02-18 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Human plasminogen catalytic domain undergoes an unusual conformational change upon activation.
J.Mol.Biol., 295, 2000
|
|
5DQL
 | |
