5ONP

Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Cd-substituted Thermolysin

Summary for 5ONP

• Entry DOI: 10.2210/pdb5onp/pdb
• Descriptor: Thermolysin, Amyloid-beta A4 protein, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: peptidase, protein-peptide complex, beta-amyloid peptide, hydrolase
• Biological source: Geobacillus stearothermophilus (Bacillus stearothermophilus); More
• Total number of polymer chains: 2
• Total formula weight: 35213.04

Authors

Leite, J.P.,Gales, L. (deposition date: 2017-08-04, release date: 2018-08-29, Last modification date: 2024-01-17)

• Primary citation: Leite, J.P.,Gales, L.; Alzheimer's A beta1-40peptide degradation by thermolysin: evidence of inhibition by a C-terminal A beta product.; FEBS Lett., 593:128-137, 2019; PubMed: 30403288; DOI: 10.1002/1873-3468.13285

Experimental method

X-RAY DIFFRACTION (1.34 Å)