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5ONP

Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Cd-substituted Thermolysin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Thermolysinpolymer31634360.31UniProt (P43133)
Pfam (PF01447)
Pfam (PF02868)
Geobacillus stearothermophilus (Bacillus stearothermophilus)Neutral protease
2B
(B)
Amyloid-beta A4 proteinpolymer5429.51UniProt (by SIFTS) (P05067)Homo sapiensABPP,APPI,APP,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta precursor protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II
3C, D, E
(A)
CALCIUM IONnon-polymer40.13Chemie (CA)
4F, G
(A)
CADMIUM IONnon-polymer112.42Chemie (CD)
5H
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
6I, J
(A, B)
waterwater18.0424Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34789.8
Non-Polymers*Number of molecules6
Total formula weight423.2
All*Total formula weight35213.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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