PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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8SU2	F96H epi-Isozizaene Synthase: complex with 3 Mg2+ and risedronate 分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, Epi-isozizaene synthase, GLYCEROL, ... 著者 Eaton, S.A, Christianson, D.W. 登録日 2023-05-11 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products. Biochemistry, 62, 2023
7N79	O2-, PLP-dependent desaturase Plu4 holo-enzyme 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Hoffarth, E.R, Ryan, K.S. 登録日 2021-06-09 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
4KXX	Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate 分子名称: (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ... 著者 Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
6E3R	Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-14 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
7NLI	S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant 分子名称: Ty1 Gag p22 著者 Cottee, M.A, Letham, S.C, Taylor, I.A. 登録日 2021-02-22 公開日 2021-10-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.119 Å) 主引用文献 Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control. Nat Commun, 12, 2021
7N1H	CryoEM structure of Venezuelan equine encephalitis virus VLP in complex with the LDLRAD3 receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid, ... 著者 Basore, K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-05-27 公開日 2021-10-13 最終更新日 2021-11-10 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor. Nature, 598, 2021
6E2F	Cryo-EM structure of human TRPV6 in complex with Calmodulin 分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-07-11 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6. Sci Adv, 4, 2018
8EG4	[iU:Ag+:iU] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5IU)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5IU)P*AP*CP*A*(AG))-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2022-09-10 公開日 2023-04-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (4.18 Å) 主引用文献 Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 35, 2023
4L0Y	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
6E2Q	Structure of human JAK2 FERM/SH2 in complex with Erythropoietin Receptor 分子名称: Erythropoietin receptor, Tyrosine-protein kinase JAK2 著者 Ferrao, R, Lupardus, P.J. 登録日 2018-07-11 公開日 2018-08-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. Elife, 7, 2018
7NIE	putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria 分子名称: Glycerol kinase, Voltage-dependent anion-selective channel protein 2 著者 Leung, M.R, Zeev-Ben-Mordehai, T. 登録日 2021-02-12 公開日 2021-10-13 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm. Proc.Natl.Acad.Sci.USA, 118, 2021
6E33	Crystal Structure of Pho7-DNA complex 分子名称: DNA (5'-D(*GP*AP*TP*TP*TP*GP*AP*AP*TP*GP*TP*CP*CP*GP*AP*AP*GP*GP*AP*T)-3'), DNA (5'-D(*TP*CP*CP*TP*TP*CP*GP*GP*AP*CP*AP*TP*TP*CP*AP*AP*AP*TP*CP*A)-3'), Uncharacterized transcriptional regulatory protein C27B12.11c, ... 著者 Garg, A, Goldgur, Y, Shuman, S. 登録日 2018-07-13 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis. Nucleic Acids Res., 46, 2018
8SP9	Crystal Structure of Coxsackievirus B3 (CVB3) Cloverleaf RNA with tRNA scaffold 分子名称: tRNA scaffold,CVB3 Cloverleaf RNA 著者 Gottipati, K, McNeme, S.C, Choi, K.H. 登録日 2023-05-02 公開日 2023-08-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structural basis for cloverleaf RNA-initiated viral genome replication. Nucleic Acids Res., 51, 2023
4L1P	Crystal Structure of Human Rtf1 Plus3 domain 分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog 著者 Wier, A.D, Heroux, A, VanDemark, A.P. 登録日 2013-06-03 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
7NHG	Crystal structure of the human METTL3-METTL14 complex with compound ASI_M3M_041 分子名称: ACETATE ION, N-[[(3R)-3-Hydroxy-1-[6-(methylamino)pyrimidin-4-yl]piperidin-3-yl]methyl]-4-(piperidin-1-ylmethyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NIA	Crystal structure of the human METTL3-METTL14 complex with compound UOZ059a 分子名称: 4-[[(3R)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-N-[[(3R)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NI9	Crystal structure of the human METTL3-METTL14 complex with compound UOZ058 分子名称: ACETATE ION, N-(((R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-(((S)-1-isopropyl-2-azaspiro[3.3]heptan-2-yl)methyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NHV	Crystal structure of the human METTL3-METTL14 complex with compound UOZ016 分子名称: (R)-N-((1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-((4,4-dimethylpiperidin-1-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
4KUX	Crystal structure of Aspergillus terreus aristolochene synthase complexed with farnesyl thiolodiphosphate (FSPP) 分子名称: Aristolochene synthase, GLYCEROL, MAGNESIUM ION, ... 著者 Chen, M, Faraldos, J.A, Al-lami, N, Janvier, M, D'Antonio, E.L, Cane, D.E, Allemann, R.K, Christianson, D.W. 登録日 2013-05-22 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry, 52, 2013
8F6T	Cryo-EM structure of alkane 1-monooxygenase AlkB-AlkG complex from Fontimonas thermophila 分子名称: Alkane 1-monooxygenase, DODECANE, FE (III) ION 著者 Chai, J, Guo, G, McSweeney, S, Shanklin, J, Liu, Q. 登録日 2022-11-17 公開日 2023-04-05 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structural basis for enzymatic terminal C-H bond functionalization of alkanes. Nat.Struct.Mol.Biol., 30, 2023
7NHH	Crystal structure of the human METTL3-METTL14 complex with compound UOZ002 分子名称: (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl)piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NI7	Crystal structure of the human METTL3-METTL14 complex with compound UOZ031 分子名称: (R)-4-((4,4-dimethylpiperidin-1-yl)methyl)-2-hydroxy-N-((3-hydroxy-1-(6-((3-(methylcarbamoyl)benzyl)amino)pyrimidin-4-yl)piperidin-3-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
4KVL	Crystal structure of Oryza sativa fatty acid alpha-dioxygenase Y379F with palmitic acid 分子名称: CALCIUM ION, CHLORIDE ION, Fatty acid alpha-oxidase, ... 著者 Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. 登録日 2013-05-22 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
6EKT	Structure of P47 from Clostridium botulinum A2 分子名称: p-47 protein 著者 Berntsson, R.P, Stenmark, P. 登録日 2017-09-27 公開日 2017-10-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster. FEBS Lett., 591, 2017
7NID	Crystal structure of the human METTL3-METTL14 complex with compound UOZ078 分子名称: (R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-(((6-((4,4-dimethylpiperidin-1-yl)methyl)naphthalen-1-yl)amino)methyl)piperidin-3-ol, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023

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