PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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5M59	Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain 分子名称: ACETATE ION, Pre-mRNA splicing helicase-like protein, Putative pre-mRNA splicing factor 著者 Absmeier, E, Becke, C, Wollenhaupt, J, Santos, K.F, Wahl, M.C. 登録日 2016-10-20 公開日 2016-12-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
5IPC	Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside thiophosphoramidate substrate complex 分子名称: 1,2-ETHANEDIOL, 5'-S-[(S)-hydroxy{[2-(1H-indol-3-yl)ethyl]amino}phosphoryl]-5'-thioguanosine, CHLORIDE ION, ... 著者 Maize, K.M, Finzel, B.C. 登録日 2016-03-09 公開日 2017-03-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry, 56, 2017
6AR1	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Nat)) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... 著者 Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. 登録日 2017-08-21 公開日 2017-11-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
5IPD	Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) nucleoside thiophosphoramidate covalent intermediate complex 分子名称: 5'-S-phosphono-5'-thioguanosine, Histidine triad nucleotide-binding protein 1 著者 Maize, K.M, Finzel, B.C. 登録日 2016-03-09 公開日 2017-03-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry, 56, 2017
6AR3	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Se-Met)) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... 著者 Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. 登録日 2017-08-21 公開日 2017-11-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
4OAQ	Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Aggrawal, N, Mandal, P.K, Gautham, N, Chadha, A. 登録日 2014-01-06 公開日 2015-02-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.858 Å) 主引用文献 Insights into the stereoselectivity of R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330: Biochemical Characterization and Crystal structure studies To be Published
6UH5	Structural basis of COMPASS eCM recognition of the H2Bub nucleosome 分子名称: Bre2, DNA (146-MER), H3 N-terminus, ... 著者 Hsu, P.L, Shi, H, Zheng, N. 登録日 2019-09-26 公開日 2019-11-20 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Mol.Cell, 76, 2019
8EUF	Class2 of the INO80-Nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. 登録日 2022-10-18 公開日 2023-07-12 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
6OXB	First bromo-adjacent homology (BAH) domain of human Polybromo-1 (PBRM1) 分子名称: CHLORIDE ION, Protein polybromo-1, SULFATE ION 著者 Petojevic, T, Holliday, M.J, Fairbrother, W.J, Cochran, A.G. 登録日 2019-05-13 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Polyvalent nucleosome recognition by Polybromo-1 anchors chromatin remodeling To Be Published
7U46	Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N 分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ... 著者 Zhou, K, Luger, K. 登録日 2022-02-28 公開日 2022-03-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.68 Å) 主引用文献 CENP-N promotes the compaction of centromeric chromatin. Nat.Struct.Mol.Biol., 29, 2022
7U47	CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and palindromic alpha satellite DNA sequence 分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ... 著者 Zhou, K, Luger, K. 登録日 2022-02-28 公開日 2022-03-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 CENP-N promotes the compaction of centromeric chromatin. Nat.Struct.Mol.Biol., 29, 2022
6O09	Structure of AtPCNA in complex with the PIP motif of ATXR6 分子名称: Proliferating cellular nuclear antigen 1, Uncharacterized protein 著者 Couture, J.F, Davarinejad, H. 登録日 2019-02-15 公開日 2019-03-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle. J. Mol. Biol., 431, 2019
6UGM	Structural basis of COMPASS eCM recognition of an unmodified nucleosome 分子名称: Bre2, DNA (146-MER), H3 N-terminus, ... 著者 Hsu, P.L, Shi, H, Zheng, N. 登録日 2019-09-26 公開日 2019-11-20 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Mol.Cell, 76, 2019
7U4D	CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and 601 DNA sequence 分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ... 著者 Zhou, K, Luger, K. 登録日 2022-02-28 公開日 2022-03-30 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 CENP-N promotes the compaction of centromeric chromatin. Nat.Struct.Mol.Biol., 29, 2022
7K6R	Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027 分子名称: 1,2-ETHANEDIOL, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one, Nucleosome-remodeling factor subunit BPTF 著者 Chan, A, Schonbrunn, E. 登録日 2020-09-21 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development. Org.Biomol.Chem., 18, 2020
8EU9	Class1 of the INO80-Nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... 著者 Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. 登録日 2022-10-18 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
1X97	Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat, 2S4S) 分子名称: (2R,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 El-Kabbani, O, Darmanin, C, Oka, M, Schulze-Briese, C, Tomizaki, T, Hazemann, I, Mitschler, A, Podjarny, A. 登録日 2004-08-19 公開日 2004-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High-Resolution Structures of Human Aldose Reductase Holoenzyme in Complex with Stereoisomers of the Potent Inhibitor Fidarestat: Stereospecific Interaction between the Enzyme and a Cyclic Imide Type Inhibitor J.Med.Chem., 47, 2004
1X96	Crystal structure of Aldose Reductase with citrates bound in the active site 分子名称: CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase 著者 El-Kabbani, O, Darmanin, C, Oka, M, Schulze-Briese, C, Tomizaki, T, Hazemann, I, Mitschler, A, Podjarny, A. 登録日 2004-08-19 公開日 2004-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High-Resolution Structures of Human Aldose Reductase Holoenzyme in Complex with Stereoisomers of the Potent Inhibitor Fidarestat: Stereospecific Interaction between the Enzyme and a Cyclic Imide Type Inhibitor J.Med.Chem., 47, 2004
6VZ4	Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102 bound to the nucleosome in ADP Beryllium Fluoride state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein ARP9, ... 著者 Leschziner, A.E, Baker, R.W. 登録日 2020-02-27 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insights into assembly and function of the RSC chromatin remodeling complex. Nat.Struct.Mol.Biol., 28, 2021
1X98	Crystal structure of Aldose Reductase complexed with 2S4R (Stereoisomer of Fidarestat, 2S4S) 分子名称: (2S,4R)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose Reductase, CITRIC ACID, ... 著者 El-Kabbani, O, Darmanin, C, Oka, M, Schulze-Briese, C, Tomizaki, T, Hazemann, I, Mitschler, A, Podjarny, A. 登録日 2004-08-19 公開日 2004-09-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High-Resolution Structures of Human Aldose Reductase Holoenzyme in Complex with Stereoisomers of the Potent Inhibitor Fidarestat: Stereospecific Interaction between the Enzyme and a Cyclic Imide Type Inhibitor J.Med.Chem., 47, 2004
1DAA	CRYSTALLOGRAPHIC STRUCTURE OF D-AMINO ACID AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE 分子名称: D-AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Sugio, S, Peisach, D, Ringe, D. 登録日 1995-06-09 公開日 1995-09-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity. Biochemistry, 34, 1995
1KI6	CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH A 5-IODOURACIL ANHYDROHEXITOL NUCLEOSIDE 分子名称: 1',5'-ANHYDRO-2',3'-DIDEOXY-2'-(5-IODOURACIL-1-YL)-D-ABABINO-HEXITOL, SULFATE ION, THYMIDINE KINASE 著者 Champness, J.N, Bennett, M.S, Wien, F, Herdewijn, P, Ostrowski, T, Summers, W.C, Sanderson, M.R. 登録日 1998-05-18 公開日 1998-12-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins, 32, 1998
3TBA	Structure of Yeast Ribonucleotide Reductase 1 Q288A with dGTP and ADP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C. 登録日 2011-08-05 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
8GXF	Pseudomonas flexibilis GCN5 family acetyltransferase 分子名称: COENZYME A, GCN5 family acetyltransferase 著者 Song, Y.J, Bao, R. 登録日 2022-09-20 公開日 2022-10-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022
8GXJ	Pseudomonas aeruginosa N-acetyltransferase domain-containing protein PA3270 分子名称: N-acetyltransferase domain-containing protein 著者 Song, Y.J, Bao, R. 登録日 2022-09-20 公開日 2022-10-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022

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