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8T0M
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Proteasome 20S core particle from Pre1-1 Pre4-1 Double mutant
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J.
登録日2023-06-01
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
8T0K
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BU of 8t0k by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-06-01
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8T0J
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Salmonella Typhimurium ArnD
分子名称: Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
著者Sousa, M.C, Munoz-Escudero, D, Lee, M.
登録日2023-06-01
公開日2023-10-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.
Biochemistry, 62, 2023
8T0I
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Backbone Dialkylation in Peptide Hairpins: (R)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0H
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Backbone Dialkylation in Peptide Hairpins: (S)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0G
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Backbone Dialkylation in Peptide Hairpins: Natural Backbone Prototype
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0E
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TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo)
分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Cheng, Y.
登録日2023-05-31
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0C
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TRPV1 in Nanodisc bound with lysophosphatidic acid in all four monomers
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Cheng, Y.
登録日2023-05-31
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0B
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Novel Domain of Unknown Function Solved with AlphaFold
分子名称: DUF1842 domain-containing protein
著者Miller, J.E, Cascio, D, Sawaya, M.R, Yeates, T.O.
登録日2023-05-31
公開日2024-01-17
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.
Acta Crystallogr D Struct Biol, 80, 2024
8T09
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Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-ethynyl-2-hydroxy-1-naphthaldehyde)
分子名称: 6-ethynyl-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Bruystens, J.G.H.
登録日2023-05-31
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T08
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Preholo-Proteasome from Pre1-1 Pre4-1 Double Mutant
分子名称: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
著者Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J.
登録日2023-05-31
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
8T07
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Structure of mouse Myomaker mutant-Y118A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T06
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Structure of mouse Myomaker mutant-R107A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T05
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Structure of Ciona Myomaker bound to Fab1A1
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T04
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BU of 8t04 by Molmil
Structure of mouse Myomaker bound to Fab18G7 in nanodiscs
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T03
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BU of 8t03 by Molmil
Structure of mouse Myomaker bound to Fab18G7 in detergent
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T01
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Solution NMR structure of a multifunctional synthetic peptide Hp-MAP3 derived from Temporin-PTa
分子名称: Hp-MAP3 peptide
著者Freitas, C.D.P, Migliolo, L, Silva, P.S, Liao, L.M.
登録日2023-05-31
公開日2024-06-12
実験手法SOLUTION NMR
主引用文献Solution NMR structure of a multifunctional synthetic peptide Hp-MAP3 derived from Temporin-PTa.
To Be Published
8SZZ
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BU of 8szz by Molmil
CryoEM Structure of Computationally Designed Nanocage O32-ZL4
分子名称: O32-ZL4 Component A, O32-ZL4 Component B, SODIUM ION
著者Weidle, C, Borst, A.
登録日2023-05-30
公開日2023-11-01
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Accurate computational design of three-dimensional protein crystals.
Nat Mater, 22, 2023
8SZY
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BU of 8szy by Molmil
Crystal Structure of Heterotrimeric Anti-TIGIT Fabs in complex with human TIGIT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BMS-986207 Fab Heavy Chain, BMS-986207 light chain, ...
著者Diong, S.J, Lee, P.S.
登録日2023-05-30
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT.
Mabs, 15, 2023
8SZX
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BU of 8szx by Molmil
Crystal structure of b'-WD40 Lys17Ala mutant
分子名称: Coatomer subunit beta'
著者Dey, D, Hasan, S.S.
登録日2023-05-30
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8SZV
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BU of 8szv by Molmil
Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog SJPYT-318
分子名称: N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-[(4-phenoxyphenyl)methyl]benzenesulfonamide, Nuclear receptor subfamily 1 group I member 2
著者Huber, A.D, Poudel, S, Miller, D.J, Li, Y, Chen, T.
登録日2023-05-30
公開日2023-10-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand.
Structure, 31, 2023
8SZU
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Structure of Kdac1-Citarinostat complex from Acinetobacter baumannii
分子名称: Citarinostat, Histone deacetylase domain-containing protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2023-05-30
公開日2023-09-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii .
Biochemistry, 62, 2023
8SZT
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Structure of Kdac1 from Acinetobacter baumannii
分子名称: CHLORIDE ION, Histone deacetylase domain-containing protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2023-05-30
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii .
Biochemistry, 62, 2023
8SZS
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Cat DHX9 bound to GDP
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Lee, Y.-T, Sickmier, E.A, Boriack-Sjodin, P.A.
登録日2023-05-30
公開日2023-09-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Development of assays to support identification and characterization of modulators of DExH-box helicase DHX9.
Slas Discov, 28, 2023
8SZR
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Dog DHX9 bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNA helicase, ...
著者Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A.
登録日2023-05-30
公開日2023-08-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Crystal structures of the DExH-box RNA helicase DHX9.
Acta Crystallogr D Struct Biol, 79, 2023

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件を2024-06-26に公開中

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