8SZY
Crystal Structure of Heterotrimeric Anti-TIGIT Fabs in complex with human TIGIT
Summary for 8SZY
Entry DOI | 10.2210/pdb8szy/pdb |
Descriptor | CHA.9.543 Fab heavy chain, CHA.9.543 light chain, BMS-986207 Fab Heavy Chain, ... (7 entities in total) |
Functional Keywords | antibody, tigit, pvr-family, immune system, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 10 |
Total formula weight | 221157.78 |
Authors | |
Primary citation | Diong, S.J.,Jashnani, A.,Drake, A.W.,Bee, C.,Findeisen, F.,Dollinger, G.,Wang, F.,Rajpal, A.,Strop, P.,Lee, P.S. Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT. Mabs, 15:2253788-2253788, 2023 Cited by PubMed: 37675979DOI: 10.1080/19420862.2023.2253788 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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