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8G9J
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BU of 8g9j by Molmil
Geometrically programmable nanomaterial construction using regularized protein building blocks
分子名称: THR1
著者Huddy, T, Bera, A.K, Baker, D.
登録日2023-02-21
公開日2024-03-13
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Blueprinting extendable nanomaterials with standardized protein blocks.
Nature, 627, 2024
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
分子名称: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
登録日2020-05-04
公開日2020-10-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
8AED
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BU of 8aed by Molmil
Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ...
著者Mittl, P, Gloegl, M.
登録日2022-07-13
公開日2023-08-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
8BAO
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BU of 8bao by Molmil
Dysgonamonadaceae bacterium CRISPR ancillary nuclease 2
分子名称: BROMIDE ION, Cyclic tetra-adenylate (cA4), DUF1887 family protein, ...
著者Li, A.W.H, Doherty, A.J.
登録日2022-10-11
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
8HNJ
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BU of 8hnj by Molmil
Domain-stabilized glutamine-binding protein
分子名称: GLUTAMINE, Glutamine ABC transporter, periplasmic glutamine-binding protein GlnH
著者Choi, S.H, Park, J.H, Seo, M.H, Park, K.W, Lee, W.K.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Domain-wise dissection of thermal stability enhancement in multidomain proteins.
Int.J.Biol.Macromol., 237, 2023
5KNG
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BU of 5kng by Molmil
CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9
分子名称: DARPIN 6G9, GLYCEROL, PHOSPHATE ION
著者Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
登録日2016-06-28
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
8BWW
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BU of 8bww by Molmil
Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs
分子名称: Thrombin light chain
著者Diehl, C.
登録日2022-12-07
公開日2023-09-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs.
Nat Commun, 14, 2023
6WXM
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BU of 6wxm by Molmil
X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 16-36
分子名称: Amyloid-beta protein, HEXANE-1,6-DIOL
著者Kreutzer, A.G, Nowick, J.S.
登録日2020-05-11
公開日2020-07-08
最終更新日2020-08-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray Crystallography Reveals Parallel and Antiparallel beta-Sheet Dimers of a beta-Hairpin Derived from A beta16-36that Assemble to Form Different Tetramers.
Acs Chem Neurosci, 11, 2020
8B45
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BU of 8b45 by Molmil
Structure of CC-Tri with Aib@b,c: CC-Tri-(UbUc)4
分子名称: 1,2-ETHANEDIOL, CC-Tri-(UbUc)4, SODIUM ION, ...
著者Kumar, P, Martin, F.J.O, Dawson, W.M, Zieleniewski, F, Woolfson, D.N.
登録日2022-09-19
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of CC-Tri with Aib@b,c: CC-Tri-(UbUc)4
To Be Published
7B4V
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BU of 7b4v by Molmil
Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
分子名称: Broadly neutralizing DARPin bnD.2, CHLORIDE ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), ...
著者Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
登録日2020-12-02
公開日2021-11-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4W
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BU of 7b4w by Molmil
Broadly neutralizing DARPin bnD.3 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.3, ...
著者Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
登録日2020-12-02
公開日2021-11-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
8G9K
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BU of 8g9k by Molmil
Geometrically programmable nanomaterial construction using regularized protein building blocks
分子名称: THR2
著者Bera, A.K, Huddy, T, Baker, D, Kang, A.
登録日2023-02-21
公開日2024-03-13
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Blueprinting extendable nanomaterials with standardized protein blocks.
Nature, 627, 2024
5KNH
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BU of 5knh by Molmil
CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13
分子名称: ACETATE ION, DARPIN 6G9, IL13
著者Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
登録日2016-06-28
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
8BU0
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BU of 8bu0 by Molmil
Crystal structure of an 8 repeat consensus TPR superhelix with calcium
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Liutkus, M, Rojas, A.L, Cortajarena, A.L.
登録日2022-11-30
公開日2023-12-13
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
8FWD
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BU of 8fwd by Molmil
Fast and versatile sequence- independent protein docking for nanomaterials design using RPXDock
分子名称: O43-rpxdoc-EK1_A, O43-rpxdoc-EK1_B
著者Skotheim, R, Borst, A.J, Baker, D.
登録日2023-01-20
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock.
Plos Comput.Biol., 19, 2023
6WSJ
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BU of 6wsj by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with cyclopeptide des4.3.1
分子名称: 1,2-ETHANEDIOL, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2020-05-01
公開日2021-04-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Nat Commun, 12, 2021
8B9Y
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BU of 8b9y by Molmil
Cysteine Synthase from Trypanosoma cruzi with PLP and OAS
分子名称: Cysteine synthase, putative, GLYCEROL, ...
著者Sowerby, K.V, Pohl, E.
登録日2022-10-10
公開日2023-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
8B9W
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BU of 8b9w by Molmil
Cysteine Synthase from Trypanosoma theileri with PLP bound
分子名称: CHLORIDE ION, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
著者Sowerby, K.V, Pohl, E.
登録日2022-10-10
公開日2023-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
8B9M
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BU of 8b9m by Molmil
Cysteine Synthase from Leishmania Infantum
分子名称: CHLORIDE ION, Cysteine synthase, GLYCEROL
著者Sowerby, K.V, Pohl, E.
登録日2022-10-06
公開日2023-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
8BGJ
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BU of 8bgj by Molmil
Crystal structure of Reverse Transcriptase domain from Caloramator australicus CART-CAPP
分子名称: L(+)-TARTARIC ACID, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
著者Li, A.W.H, Doherty, A.J.
登録日2022-10-27
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
8CHY
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BU of 8chy by Molmil
Crystal structure of an 8-repeat consensus TPR superhelix with Zinc.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Liutkus, M, Rojas, A.L, Cortajarena, A.L.
登録日2023-02-08
公開日2024-02-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
8CH0
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BU of 8ch0 by Molmil
Crystal structure of an 8-repeat consensus TPR superhelix with Gadolinium.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ...
著者Liutkus, M, Rojas, A.L, Cortajarena, A.L.
登録日2023-02-06
公開日2024-02-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
8CIG
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BU of 8cig by Molmil
Crystal structure of an 8-repeat consensus TPR superhelix in tris Buffer with Calcium.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Liutkus, M, Rojas, A.L, Cortajarena, A.L.
登録日2023-02-09
公開日2024-02-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Diverse crystalline protein scaffolds through metal-dependent polymorphism.
Protein Sci., 33, 2024
5H79
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BU of 5h79 by Molmil
Crystal structure of a repeat protein with three Protein A repeat module
分子名称: Immunoglobulin G-binding protein A
著者Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
登録日2016-11-17
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
5H7B
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BU of 5h7b by Molmil
Crystal structure of a repeat protein with five Protein A repeat modules
分子名称: Immunoglobulin G-binding protein A
著者Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
登録日2016-11-17
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017

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