6WXM

X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 16-36

Summary for 6WXM

• Entry DOI: 10.2210/pdb6wxm/pdb
• Descriptor: Amyloid-beta protein, HEXANE-1,6-DIOL (3 entities in total)
• Functional Keywords: oligomer, alzheimer's, de novo protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 11
• Total formula weight: 28536.03

Authors

Kreutzer, A.G.,Nowick, J.S. (deposition date: 2020-05-11, release date: 2020-07-08, Last modification date: 2020-08-26)

• Primary citation: Kreutzer, A.G.,Samdin, T.D.,Guaglianone, G.,Spencer, R.K.,Nowick, J.S.; X-ray Crystallography Reveals Parallel and Antiparallel beta-Sheet Dimers of a beta-Hairpin Derived from A beta16-36that Assemble to Form Different Tetramers.; Acs Chem Neurosci, 11:2340-2347, 2020; PubMed: 32584538; DOI: 10.1021/acschemneuro.0c00290

Experimental method

X-RAY DIFFRACTION (2.3 Å)