PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

---

8QXT	CryoEM structure of a GroEL14-GroES7 complex in presence of ADP-BeFx with narrow GroEL7 trans ring conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... 著者 Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. 登録日 2023-10-25 公開日 2024-07-03 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Visualizing chaperonin function in situ by cryo-electron tomography Nature, 2024
8EJ1	Dephosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) 分子名称: Cystic fibrosis transmembrane conductance regulator 著者 Fiedorczuk, K, Chen, J. 登録日 2022-09-16 公開日 2022-10-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators. Science, 378, 2022
6D5B	Structure of Caldicellulosiruptor danielii CBM3 module of glycoside hydrolase WP_045175321 分子名称: CALCIUM ION, glycoside hydrolase WP_045175321 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2018-04-19 公開日 2019-04-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Novel multidomain, multifunctional glycoside hydrolases from highly lignocellulolytic Caldicellulosiruptor species AIChE J., 2019
7NGP	D1-state of wild type human mitochondrial LONP1 protease 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial 著者 Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. 登録日 2021-02-09 公開日 2021-04-28 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
7NGL	R-state of wild type human mitochondrial LONP1 protease bound to endogenous ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial 著者 Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. 登録日 2021-02-09 公開日 2021-04-28 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
4K90	Extracellular metalloproteinase from Aspergillus 分子名称: BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ... 著者 Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I. 登録日 2013-04-19 公開日 2013-10-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus. Acta Crystallogr.,Sect.D, 69, 2013
8EIG	The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445) and ATP/Mg 分子名称: (6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Fiedorczuk, K, Chen, J. 登録日 2022-09-15 公開日 2022-10-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators. Science, 378, 2022
6D7F	Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide 分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-24 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
8EIO	The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445), lumacaftor (VX-809) and ATP/Mg 分子名称: (6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Fiedorczuk, K, Chen, J. 登録日 2022-09-15 公開日 2022-10-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators. Science, 378, 2022
8EIQ	The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with Trikafta [elexacaftor (VX-445), tezacaftor (VX-661), ivacaftor (VX-770)] and ATP/Mg 分子名称: (6P)-N-(1,3-dimethyl-1H-pyrazole-4-sulfonyl)-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Fiedorczuk, K, Chen, J. 登録日 2022-09-15 公開日 2022-10-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators. Science, 378, 2022
6D9A	Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-GalNAc (open, reduced) 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, SODIUM ION, ... 著者 Wangkanont, K, Kiessling, L.L, Forest, K.T. 登録日 2018-04-28 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Substrate recognition by FAD in UDP-galactopyranose mutase To be published
8EW3	Cryo EM structure of Vibrio cholerae NQR 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit A, ... 著者 Fuller, J.R, Juarez, O. 登録日 2022-10-21 公開日 2022-11-16 実験手法 ELECTRON MICROSCOPY (2.65159 Å) 主引用文献 Novel cofactor binding motifs, electron transfer and ion pumping mechanisms of the respiratory complex NQR To Be Published
8EP1	Eag Kv channel with voltage sensor in the down conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EH2	Short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii 分子名称: SDR family oxidoreductase 著者 Shaw, K. 登録日 2022-09-13 公開日 2022-11-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii To Be Published
8EOW	Eag Kv channel with voltage sensor in the up conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
6D5D	Structure of Caldicellulosiruptor danielii GH48 module of glycoside hydrolase WP_045175321 分子名称: CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, glycoside hydrolase WP_045175321 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2018-04-19 公開日 2019-04-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel multidomain, multifunctional glycoside hydrolases from highly lignocellulolytic Caldicellulosiruptor species AIChE J., 2019
4KA2	Crystal structure of CD4-mimetic miniprotein M48U12 in complex with HIV-1 YU2 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 YU2 gp120, M48U12 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-21 公開日 2013-06-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Interfacial Cavity Filling To Optimize CD4-Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein. J.Med.Chem., 56, 2013
8EZ0	Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Symmetric conformation 分子名称: Insulin, Insulin receptor 著者 Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. 登録日 2022-10-29 公開日 2022-11-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor. Elife, 11, 2022
4KDL	Crystal structure of p97/VCP N in complex with OTU1 UBXL 分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1 著者 Kim, S.J, Kim, E.E. 登録日 2013-04-25 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP). J.Biol.Chem., 289, 2014
6DAX	X-ray crystal structure of VioC bound to Fe(II), L-homoarginine, and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent L-arginine hydroxylase, FE (II) ION, ... 著者 Dunham, N.P, Mitchell, A.J, Boal, A.K. 登録日 2018-05-02 公開日 2018-05-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
7NDH	Crystal structure of ZC3H12C PIN domain 分子名称: 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, SODIUM ION 著者 Garg, A, Heinemann, U. 登録日 2021-02-01 公開日 2021-05-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
7NDI	Crystal structure of ZC3H12C PIN domain with Mg2+ Ion 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Probable ribonuclease ZC3H12C, ... 著者 Garg, A, Heinemann, U. 登録日 2021-02-01 公開日 2021-05-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.875 Å) 主引用文献 PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
6DC5	RSV prefusion F in complex with AM22 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Jones, H.G, McLellan, J.S. 登録日 2018-05-04 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
7NDK	Crystal structure of ZC3H12C PIN catalytic mutant 分子名称: Probable ribonuclease ZC3H12C, SODIUM ION 著者 Garg, A, Heinemann, U. 登録日 2021-02-01 公開日 2021-05-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
8EYX	Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 1 分子名称: Insulin, Insulin receptor 著者 Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. 登録日 2022-10-29 公開日 2022-11-09 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor. Elife, 11, 2022

<1406140714081409141014111412141314141415141614171418141914201421>