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2K50
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Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.
分子名称: Replication factor A related protein
著者Rossi, P, Xiao, R, Maglaqui, M, Foote, E.L, Ciccosanti, C, Swapna, G, Acton, T.B, Rost, B, Everett, J.K, Jiang, M, Nair, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-23
公開日2008-07-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.
To be Published
2KFE
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BU of 2kfe by Molmil
Solution structure of meucin-24
分子名称: meucin-24
著者Du, W, Xu, J, Gao, B, Zhu, S.
登録日2009-02-18
公開日2010-01-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Characterization of two linear cationic antimalarial peptides in the scorpion Mesobuthus eupeus
Biochimie, 92, 2010
3VQ5
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BU of 3vq5 by Molmil
HIV-1 IN core domain in complex with N-METHYL-1-(4-METHYL-2-PHENYL-1,3-THIAZOL-5-YL)METHANAMINE
分子名称: CADMIUM ION, CHLORIDE ION, N-methyl-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanamine, ...
著者Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J.
登録日2012-03-20
公開日2013-01-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
3RH2
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BU of 3rh2 by Molmil
Crystal structure of a TetR-like transcriptional regulator (Sama_0099) from Shewanella amazonensis SB2B at 2.42 A resolution
分子名称: GLYCEROL, Hypothetical TetR-like transcriptional regulator, PHOSPHATE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2011-04-11
公開日2011-05-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal structure of a Hypothetical TetR-like transcriptional regulator (Sama_0099) from SHEWANELLA AMAZONENSIS SB2B at 2.42 A resolution
To be published
2L54
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BU of 2l54 by Molmil
Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A)
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Zhao, J, Pervushin, K, Feng, S, Droge, P.
登録日2010-10-24
公開日2011-01-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Alternate rRNA secondary structures as regulators of translation
Nat.Struct.Mol.Biol., 18, 2011
1X78
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BU of 1x78 by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-244
分子名称: Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
著者Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
登録日2004-08-13
公開日2005-03-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
5A3U
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BU of 5a3u by Molmil
HIF prolyl hydroxylase 2 (PHD2/EGLN1) in complex with 6-(5-oxo-4-(1H- 1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid
分子名称: 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid, EGL NINE HOMOLOG 1, MANGANESE (II) ION
著者Chowdhury, R, Gomez-Perez, V, Schofield, C.J.
登録日2015-06-03
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.
Plos One, 10, 2015
4L02
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BU of 4l02 by Molmil
Crystal Structure of SphK1 with inhibitor
分子名称: (2R,4S)-1-[2-(4-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino}phenyl)ethyl]-2-(hydroxymethyl)piperidin-4-ol, Sphingosine kinase 1
著者Min, X, Walker, N, Wang, Z.
登録日2013-05-30
公開日2013-07-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5AGY
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BU of 5agy by Molmil
CRYSTAL STRUCTURE OF A TAU CLASS GST MUTANT FROM GLYCINE
分子名称: 4-NITROPHENYL METHANETHIOL, GLUTATHIONE S-TRANSFERASE, PHOSPHATE ION, ...
著者Axarli, I, Muleta, A.W, Vlachakis, D, Kossida, S, Kotzia, G, Dhavala, P, Papageorgiou, A.C, Labrou, N.E.
登録日2015-02-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Directed Evolution of Tau Class Glutathione Transferases Reveals a Site that Regulates Catalytic Efficiency and Masks Cooperativity.
Biochem.J., 473, 2016
1X7B
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BU of 1x7b by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041
分子名称: 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1
著者Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
登録日2004-08-13
公開日2005-03-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
7ZPM
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BU of 7zpm by Molmil
Influenza A/H7N9 polymerase apo-protein dimer complex
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
著者Cusack, S, Kouba, T.
登録日2022-04-27
公開日2022-12-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7BZD
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BU of 7bzd by Molmil
Structure of Bacillus subtilis HxlR, wild type
分子名称: HTH-type transcriptional activator HxlR
著者Zhu, R, Chen, P.R.
登録日2020-04-27
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.612 Å)
主引用文献Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction.
Nat Commun, 12, 2021
7BZE
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BU of 7bze by Molmil
Structure of Bacillus subtilis HxlR, K13A mutant
分子名称: DI(HYDROXYETHYL)ETHER, HTH-type transcriptional activator HxlR
著者Zhu, R, Chen, P.R.
登録日2020-04-27
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.658 Å)
主引用文献Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction.
Nat Commun, 12, 2021
1XAP
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BU of 1xap by Molmil
Structure of the ligand binding domain of the Retinoic Acid Receptor beta
分子名称: 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID, Retinoic acid receptor beta
著者Germain, P, Kammerer, S, Peluso-Iltis, C, Tortolani, D, Zusi, F.C, Starrett, J, Lapointe, P, Daris, J.P, Marinier, A, De Lera, A.R, Rochel, N, Gronemeyer, H.
登録日2004-08-26
公開日2004-11-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rational design of RAR-selective ligands revealed by RARbeta crystal structure
Embo Rep., 5, 2004
7ZPL
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BU of 7zpl by Molmil
Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook
分子名称: 5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ...
著者Cusack, S, Kouba, T.
登録日2022-04-27
公開日2022-12-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
1XDK
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BU of 1xdk by Molmil
Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator
分子名称: (9cis)-retinoic acid, Retinoic acid receptor RXR-alpha, Retinoic acid receptor, ...
著者Pogenberg, V, Guichou, J.F, Vivat-Hannah, V, Kammerer, S, Perez, E, Germain, P, De Lera, A.R, Gronemeyer, H, Royer, C.A, Bourguet, W.
登録日2004-09-07
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
J.Biol.Chem., 280, 2005
6KD6
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BU of 6kd6 by Molmil
Shuguo PWWP domain
分子名称: LD23804p
著者Liu, Y.C, Huang, Y.
登録日2019-07-01
公開日2020-07-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Shuguo PWWP domain
To Be Published
5AN3
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BU of 5an3 by Molmil
Structure of an Sgt1-Skp1 Complex
分子名称: SGT1, SUPPRESSOR OF KINETOCHORE PROTEIN 1
著者Willhoft, O, Vaughan, C.K.
登録日2015-09-03
公開日2017-02-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores.
Sci Rep, 7, 2017
1Z0X
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BU of 1z0x by Molmil
Crystal structure of transcriptional regulator, tetR Family from Enterococcus faecalis V583
分子名称: CHLORIDE ION, transcriptional regulator, TetR family
著者Chang, C, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-03-02
公開日2005-04-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of transcriptional regulator, tetR Family from Enterococcus faecalis V583
To be Published
6H02
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BU of 6h02 by Molmil
Crystal structure of human Mediator subunit MED23
分子名称: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23
著者Clantin, B, Monte, D, Villeret, V.
登録日2018-07-06
公開日2018-08-29
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human Mediator subunit MED23.
Nat Commun, 9, 2018
6GYT
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BU of 6gyt by Molmil
Transcription factor dimerization activates the p300 acetyltransferase
分子名称: Histone H4, Histone acetyltransferase p300, ZINC ION
著者Panne, D, Ortega, E.
登録日2018-07-01
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Transcription factor dimerization activates the p300 acetyltransferase.
Nature, 562, 2018
4MEM
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BU of 4mem by Molmil
Crystal Structure of the rat USP11 DUSP-UBL domains
分子名称: Ubiquitin carboxyl-terminal hydrolase 11
著者Harper, S, Gratton, H.E, Cornaciu, I, Oberer, M, Scott, D.J, Emsley, J, Dreveny, I.
登録日2013-08-27
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains.
Biochemistry, 53, 2014
6DV5
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BU of 6dv5 by Molmil
Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution
分子名称: Heat shock protein beta-1
著者Aguda, A.H, Brayer, G.D.
登録日2018-06-22
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization.
To Be Published
6GVY
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BU of 6gvy by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
分子名称: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2018-06-21
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
6GWK
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BU of 6gwk by Molmil
The crystal structure of Hfq from Caulobacter crescentus
分子名称: RNA-binding protein Hfq
著者Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W.
登録日2018-06-25
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation.
Proc.Natl.Acad.Sci.USA, 116, 2019

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