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1BFF
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THE 154 AMINO ACID FORM OF HUMAN BASIC FIBROBLAST GROWTH FACTOR
分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, PHOSPHATE ION
著者Kastrup, J.S, Eriksson, E.S.
登録日1996-12-06
公開日1997-06-16
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Acta Crystallogr.,Sect.D, 53, 1997
1J7T
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BU of 1j7t by Molmil
Complex between Paromomycin and the 16S-rRNA A-site at 2.5 A resolution
分子名称: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', PAROMOMYCIN
著者Vicens, Q, Westhof, E.
登録日2001-05-18
公開日2002-05-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site.
Structure, 9, 2001
1J7Y
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BU of 1j7y by Molmil
Crystal structure of partially ligated mutant of HbA
分子名称: CARBON MONOXIDE, Hemoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Miele, A.E, Draghi, F, Arcovito, A, Bellelli, A, Brunori, M, Travaglini-Allocatelli, C, Vallone, B.
登録日2001-05-19
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Control of heme reactivity by diffusion: structural basis and functional characterization in hemoglobin mutants.
Biochemistry, 40, 2001
2ZEH
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BU of 2zeh by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201Q at 1.8 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
1EY3
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BU of 1ey3 by Molmil
STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA
分子名称: 4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA, ENOYL-COA HYDRATASE
著者Bahnson, B.J, Anderson, V.E, Petsko, G.A.
登録日2000-05-05
公開日2002-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion.
Biochemistry, 41, 2002
5LO4
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BU of 5lo4 by Molmil
Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPa-CH3
著者Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
3F83
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BU of 3f83 by Molmil
Structure of fusion complex of the minor pilin CfaE and major pilin CfaB of CFA/I pili from ETEC E. coli
分子名称: Fusion of the minor pilin CfaE and major pilin CfaB, SODIUM ION, SULFATE ION
著者Xia, D, Li, Y.F.
登録日2008-11-11
公開日2009-08-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
2JV6
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BU of 2jv6 by Molmil
YF ED3 Protein NMR Structure
分子名称: Envelope protein E
著者Volk, D.E, Gandham, S.H.A, May, F.J, Anderson, A, Barrett, A.D.T, Gorenstein, D.G.
登録日2007-09-12
公開日2008-09-16
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Yellow Fever Virus Envelope Protein Domain III: A Convergence of Structure and Phylogenetics
To be Published
3NXX
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BU of 3nxx by Molmil
Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro-2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
分子名称: 5-[(1E)-2-(2-methoxyphenyl)-4-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V.
登録日2010-07-14
公開日2010-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.
Acta Crystallogr.,Sect.D, 66, 2010
2K06
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BU of 2k06 by Molmil
Solution structure of the aminoterminal domain of E. coli NusG
分子名称: Transcription antitermination protein nusG
著者Schweimer, K, Scheckenhofer, U, Roesch, P.
登録日2008-01-25
公開日2009-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators.
J.Mol.Biol., 391, 2009
2M3J
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BU of 2m3j by Molmil
Solution Structure of Marine Sponge-Derived Asteropsin E Which is Highly Resistant to Gastrointestinal Proteases
分子名称: Asteropsin_E
著者Li, H, Jung, J.H.
登録日2013-01-21
公開日2014-03-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution Structure of Marine Sponge-Derived Asteropsin E Which is Highly Resistant to Gastrointestinal Proteases
To be Published
1PD1
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BU of 1pd1 by Molmil
Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide containing the DxE cargo sorting signal of yeast Sys1 protein
分子名称: DxE cargo sorting signal peptide of yeast Sys1 protein, Protein transport protein Sec24, ZINC ION
著者Mossessova, E, Bickford, L.C, Goldberg, J.
登録日2003-05-18
公開日2003-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献SNARE selectivity of the COPII coat.
Cell(Cambridge,Mass.), 114, 2003
1PD0
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BU of 1pd0 by Molmil
Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide from the SNARE protein Sed5 (yeast syntaxin-5)
分子名称: COPII-binding peptide of the integral membrane protein SED5, Protein transport protein Sec24, ZINC ION
著者Mossessova, E, Bickford, L.C, Goldberg, J.
登録日2003-05-18
公開日2003-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献SNARE selectivity of the COPII coat.
Cell(Cambridge,Mass.), 114, 2003
3NZK
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BU of 3nzk by Molmil
Structure of LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor
分子名称: GLYCEROL, N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ...
著者Cole, K.E, Christianson, D.W.
登録日2010-07-16
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 .
Biochemistry, 50, 2010
6EK1
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BU of 6ek1 by Molmil
Crystal structure of Type IIP restriction endonuclease PfoI
分子名称: 1,2-ETHANEDIOL, restriction endonuclease PfoI
著者Tamulaitiene, G, Manakova, E, Jovaisaite, V, Grazulis, S, Siksnys, V.
登録日2017-09-25
公開日2018-10-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.
Nucleic Acids Res., 47, 2019
5FEQ
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BU of 5feq by Molmil
EGFR KINASE DOMAIN IN COMPLEX WITH A COVALENT AMINOBENZIMIDAZOLE
分子名称: Epidermal growth factor receptor, ~{N}-[1-[(3~{R})-1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl]-7-methyl-benzimidazol-2-yl]-2-methyl-pyridine-4-carboxamide
著者DiDonato, M, Spraggon, G.
登録日2015-12-17
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers.
J.Med.Chem., 59, 2016
1DPS
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BU of 1dps by Molmil
THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA
分子名称: DPS, SODIUM ION
著者Grant, R.A, Filman, D.J, Finkel, S.E, Kolter, R, Hogle, J.M.
登録日1998-02-23
公開日1998-09-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of Dps, a ferritin homolog that binds and protects DNA.
Nat.Struct.Biol., 5, 1998
3RLU
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BU of 3rlu by Molmil
Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase
著者Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C.
登録日2011-04-20
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry, 51, 2012
2MFI
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BU of 2mfi by Molmil
Domain 1 of E. coli ribosomal protein S1
分子名称: 30S ribosomal protein S1
著者Giraud, P, Crechet, J, Bontems, F, Uzan, M, Sizun, C.
登録日2013-10-11
公開日2014-05-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Resonance assignment of the ribosome binding domain of E. coli ribosomal protein S1.
Biomol.Nmr Assign., 9, 2015
2MFL
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BU of 2mfl by Molmil
Domain 2 of E. coli ribosomal protein S1
分子名称: 30S ribosomal protein S1
著者Giraud, P, Crechet, J, Bontems, F, Uzan, M, Sizun, C.
登録日2013-10-12
公開日2014-05-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Resonance assignment of the ribosome binding domain of E. coli ribosomal protein S1.
Biomol.Nmr Assign., 9, 2015
3F64
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BU of 3f64 by Molmil
F17a-G lectin domain with bound GlcNAc(beta1-O)paranitrophenyl ligand
分子名称: 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, F17a-G
著者Buts, L, De Boer, A, Olsson, J.D.M, Jonckheere, W, De Kerpel, M, De Genst, E, Guerardel, Y, Willaert, R, Wyns, L, Wuhrer, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2008-11-05
公開日2009-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli.
Biology (Basel), 2, 2013
1ICV
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BU of 1icv by Molmil
THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID
分子名称: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE
著者Lovering, A.L, Hyde, E.I, Searle, P.F, White, S.A.
登録日2001-04-02
公開日2001-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
J.Mol.Biol., 309, 2001
5LO2
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BU of 5lo2 by Molmil
Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPaTyr
著者Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
5LO3
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Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPaOMe
著者Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
3FNV
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BU of 3fnv by Molmil
Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2
分子名称: CDGSH iron sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Conlan, A.R, Axelrod, H.L, Cohen, A.E, Abresch, E.C, Yee, D, Zuris, J, Nechushtai, R, Jennings, P.A, Paddock, M.L.
登録日2008-12-26
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2.
J.Mol.Biol., 392, 2009

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