4EAN
 
 | | 1.75A resolution structure of indole bound beta-glycosidase (W33G) from sulfolobus solfataricus | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-galactosidase, CHLORIDE ION, ... | | 著者 | Lovell, S, Battaile, K.P, Deckert, K, Brunner, L.C, Budiardjo, S.J, Karanicolas, J. | | 登録日 | 2012-03-22 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Designing allosteric control into enzymes by chemical rescue of structure.
J.Am.Chem.Soc., 134, 2012
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1P37
 | | T4 LYSOZYME CORE REPACKING BACK-REVERTANT L102M/CORE10 | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-16 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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1P3N
 | | CORE REDESIGN BACK-REVERTANT I103V/CORE10 | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-17 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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4EJY
 | | Structure of MBOgg1 in complex with high affinity DNA ligand | | 分子名称: | 3-Methyladenine DNA glycosylase, DNA (5'-D(*AP*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*T*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), ... | | 著者 | Jiang, T, Yu, H.J, Bi, L.J, Zhang, X.E, Yang, M.Z. | | 登録日 | 2012-04-08 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of MBOgg1 in complex with two abasic DNA ligands
J.Struct.Biol., 181, 2013
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2YOC
 | | Crystal structure of PulA from Klebsiella oxytoca | | 分子名称: | CALCIUM ION, PULLULANASE, SULFATE ION | | 著者 | Francetic, O, Mechaly, A.E, Tello-Manigne, D, Buschiazzo, A, Bernarde, C, Nadeau, N, Pugsley, A.P, Alzari, P.M. | | 登録日 | 2012-10-23 | | 公開日 | 2013-11-06 | | 最終更新日 | 2016-01-20 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis
Structure, 24, 2016
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4EF8
 | | Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with Phenyl isothiocyanate | | 分子名称: | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | 著者 | Pinheiro, M.P, Emery, F.S, Nonato, M.C. | | 登録日 | 2012-03-29 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase.
Curr.Pharm.Des., 19, 2013
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1P6B
 | | X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T | | 分子名称: | DIETHYL 4-METHYLBENZYLPHOSPHONATE, ETHYL DIHYDROGEN PHOSPHATE, Parathion hydrolase, ... | | 著者 | Hill, C.M, Li, W, Thoden, J.B, Holden, H.M, Raushel, F.M. | | 登録日 | 2003-04-29 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
J.Am.Chem.Soc., 125, 2003
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1ORW
 | | Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor | | 分子名称: | (2S)-PYRROLIDIN-2-YLMETHYLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. | | 登録日 | 2003-03-16 | | 公開日 | 2003-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
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1P8M
 | | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | | 分子名称: | Arginase 1, MANGANESE (II) ION | | 著者 | Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W. | | 登録日 | 2003-05-07 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I.
Biochemistry, 42, 2003
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3THY
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1OJJ
 | | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | | 登録日 | 2003-07-10 | | 公開日 | 2004-01-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants
Chem.Biol., 10, 2003
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1OLS
 | | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase | | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ... | | 著者 | Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | | 登録日 | 2003-08-12 | | 公開日 | 2003-08-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site.
J.Biol.Chem., 278, 2003
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3STG
 | | Crystal structure of A58P, DEL(N59), and loop 7 truncated mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION | | 著者 | Allison, T.M, Jameson, G.B, Parker, E.J. | | 登録日 | 2011-07-09 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase
Biochemistry, 50, 2011
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1ONX
 | | Crystal structure of isoaspartyl dipeptidase from escherichia coli complexed with aspartate | | 分子名称: | ASPARTIC ACID, Isoaspartyl dipeptidase, ZINC ION | | 著者 | Thoden, J.B, Marti-Arbona, R, Raushel, F.M, Holden, H.M. | | 登録日 | 2003-03-02 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Resolution X-ray Structure of Isoaspartyl
Dipeptidase from Escherichia coli
Biochemistry, 42, 2003
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4ETC
 | | Lysozyme, room temperature, 24 kGy dose | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Boutet, S, Lomb, L, Williams, G, Barends, T, Aquila, A, Doak, R.B, Weierstall, U, DePonte, D, Steinbrener, J, Shoeman, R, Messerschmidt, M, Barty, A, White, T, Kassemeyer, S, Kirian, R, Seibert, M, Montanez, P, Kenney, C, Herbst, R, Hart, P, Pines, J, Haller, G, Gruner, S, Philllip, H, Tate, M, Hromalik, M, Koerner, L, van Bakel, N, Morse, J, Ghonsalves, W, Arnlund, D, Bogan, M, Calemann, C, Fromme, R, Hampton, C, Hunter, M, Johansson, L, Katona, G, Kupitz, C, Liang, M, Martin, A, Nass, K, Redecke, L, Stellato, F, Timneanu, N, Wang, D, Zatsepin, N, Schafer, D, Defever, K, Neutze, R, Fromme, P, Spence, J, Chapman, H, Schlichting, I. | | 登録日 | 2012-04-24 | | 公開日 | 2012-06-13 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.906 Å) | | 主引用文献 | High-resolution protein structure determination by serial femtosecond crystallography.
Science, 337, 2012
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4ETL
 | | Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum F258A mutation | | 分子名称: | COBALT (II) ION, Phenylalanine-4-hydroxylase | | 著者 | Ronau, J.A, Paul, L.P, Corn, I.R, Wagner, K.T, Abu-Omar, M.M, Das, C. | | 登録日 | 2012-04-24 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | An additional substrate binding site in a bacterial phenylalanine hydroxylase.
Eur.Biophys.J., 42, 2013
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1OP9
 | | Complex of human lysozyme with camelid VHH HL6 antibody fragment | | 分子名称: | HL6 camel VHH fragment, Lysozyme C | | 著者 | Dumoulin, M, Last, A.M, Desmyter, A, Decanniere, K, Canet, D, Larsson, G, Spencer, A, Archer, D.B, Sasse, J, Muyldermans, S, Wyns, L, Redfield, C, Matagne, A, Robinson, C.V, Dobson, C.M. | | 登録日 | 2003-03-05 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme
Nature, 424, 2003
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1P64
 | | T4 LYSOZYME CORE REPACKING MUTANT L133F/TA | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-28 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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1OR0
 | | Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation | | 分子名称: | 1,2-ETHANEDIOL, Glutaryl 7-Aminocephalosporanic Acid Acylase, glutaryl acylase | | 著者 | Kim, J.K, Yang, I.S, Rhee, S, Dauter, Z, Lee, Y.S, Park, S.S, Kim, K.H. | | 登録日 | 2003-03-11 | | 公開日 | 2004-03-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation
Biochemistry, 42, 2003
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2Y9Y
 | | Chromatin Remodeling Factor ISW1a(del_ATPase) | | 分子名称: | IMITATION SWITCH PROTEIN 1 (DEL_ATPASE), ISWI ONE COMPLEX PROTEIN 3 | | 著者 | Yamada, K, Frouws, T.D, Angst, B, Fitzgerald, D.J, DeLuca, C, Schimmele, K, Sargent, D.F, Richmond, T.J. | | 登録日 | 2011-02-17 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structure and Mechanism of the Chromatin Remodelling Factor Isw1A.
Nature, 472, 2011
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3THE
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2YBB
 | | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, CARDIOLIPIN, ... | | 著者 | Althoff, T, Mills, D.J, Popot, J.-L, Kuehlbrandt, W. | | 登録日 | 2011-03-02 | | 公開日 | 2011-10-19 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (19 Å) | | 主引用文献 | Arrangement of Electron Transport Chain Components in Bovine Mitochondrial Supercomplex I(1)III(2)Iv(1).
Embo J., 30, 2011
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4EWX
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-04-28 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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1OUD
 | | CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V121A MUTANT | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Fujii, S, Yutani, K. | | 登録日 | 1996-08-23 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry, 36, 1997
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4EQV
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