1P6B

X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T

Summary for 1P6B

Entry DOI	10.2210/pdb1p6b/pdb
Descriptor	Parathion hydrolase, ZINC ION, DIETHYL 4-METHYLBENZYLPHOSPHONATE, ... (5 entities in total)
Functional Keywords	metalloenzyme, tim barrel, nerve agents, hydrolase
Biological source	Flavobacterium sp.
Cellular location	Cell membrane ; Peripheral membrane protein : P0A433
Total number of polymer chains	2
Total formula weight	73663.63
Authors	Hill, C.M.,Li, W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. (deposition date: 2003-04-29, release date: 2003-09-16, Last modification date: 2023-11-15)
Primary citation	Hill, C.M.,Li, W.S.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site. J.Am.Chem.Soc., 125:8990-8991, 2003 Cited by PubMed: 15369336 DOI: 10.1021/ja0358798 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation