PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

---

3ZT7	GlgE isoform 1 from Streptomyces coelicolor with beta-cyclodextrin and maltose bound 分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), PUTATIVE GLUCANOHYDROLASE PEP1A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Syson, K, Stevenson, C.E.M, Rejzek, M, Fairhurst, S.A, Nair, A, Bruton, C.J, Field, R.A, Chater, K.F, Lawson, D.M, Bornemann, S. 登録日 2011-07-01 公開日 2011-09-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a Streptomyces Maltosyltransferase Glge: A Homologue of a Genetically Validated Anti-Tuberculosis Target. J.Biol.Chem., 286, 2011
2M7S	NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1 分子名称: Serine/arginine-rich splicing factor 1 著者 Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2013-04-29 公開日 2013-05-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1 To be Published
3RZE	Structure of the human histamine H1 receptor in complex with doxepin 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ... 著者 Shimamura, T, Han, G.W, Shiroishi, M, Weyand, S, Tsujimoto, H, Winter, G, Katritch, V, Abagyan, R, Cherezov, V, Liu, W, Kobayashi, T, Stevens, R, Iwata, S, GPCR Network (GPCR) 登録日 2011-05-11 公開日 2011-06-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the human histamine H1 receptor complex with doxepin. Nature, 475, 2011
1HBN	METHYL-COENZYME M REDUCTASE 分子名称: 1-THIOETHANESULFONIC ACID, CHLORIDE ION, Coenzyme B, ... 著者 Ermler, U, Grabarse, W. 登録日 2001-04-20 公開日 2001-08-16 最終更新日 2025-04-09 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding J.Mol.Biol., 309, 2001
3ZT6	GlgE isoform 1 from Streptomyces coelicolor with alpha-cyclodextrin and maltose bound 分子名称: Cyclohexakis-(1-4)-(alpha-D-glucopyranose), PUTATIVE GLUCANOHYDROLASE PEP1A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Syson, K, Stevenson, C.E.M, Rejzek, M, Fairhurst, S.A, Nair, A, Bruton, C.J, Field, R.A, Chater, K.F, Lawson, D.M, Bornemann, S. 登録日 2011-07-01 公開日 2011-09-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure of a Streptomyces Maltosyltransferase Glge: A Homologue of a Genetically Validated Anti-Tuberculosis Target. J.Biol.Chem., 286, 2011
3SA5	Crystal structure of wild-type HIV-1 protease in complex with AF69 分子名称: ACETATE ION, N-{(2S,3R)-4-[(1,3-benzothiazol-6-ylsulfonyl)(3-phenylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}-3-hydroxybenzamide, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
1NA0	Design of Stable alpha-Helical Arrays from an Idealized TPR Motif 分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, ACETATE ION, CHLORIDE ION, ... 著者 Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. 登録日 2002-11-26 公開日 2003-06-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design of Stable alpha-Helical Arrays from an Idealized TPR Motif Structure, 11, 2003
4DUS	Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Sickmier, E.A. 登録日 2012-02-22 公開日 2012-10-10 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012
2HYR	Crystal structure of a complex of griffithsin with maltose 分子名称: 1,2-ETHANEDIOL, Griffithsin, MAGNESIUM ION, ... 著者 Ziolkowska, N.E, Wlodawer, A. 登録日 2006-08-07 公開日 2007-04-24 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin. Proteins, 67, 2007
2D81	PHB depolymerase (S39A) complexed with R3HB trimer 分子名称: (1R)-3-{[(1R)-3-METHOXY-1-METHYL-3-OXOPROPYL]OXY}-1-METHYL-3-OXOPROPYL (3R)-3-HYDROXYBUTANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHB depolymerase 著者 Hisano, T, Kasuya, K, Saito, T, Iwata, T, Miki, K. 登録日 2005-11-30 公開日 2006-01-31 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 The Crystal Structure of Polyhydroxybutyrate Depolymerase from Penicillium funiculosum Provides Insights into the Recognition and Degradation of Biopolyesters J.Mol.Biol., 356, 2006
3ZRY	Rotor architecture in the F(1)-c(10)-ring complex of the yeast F-ATP synthase 分子名称: ATP SYNTHASE CATALYTIC SECTOR F1 EPSILON SUBUNIT, ATP SYNTHASE SUBUNIT 9, MITOCHONDRIAL, ... 著者 Giraud, M.-F, Dautant, A. 登録日 2011-06-21 公開日 2012-01-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 Rotor Architecture in the Yeast and Bovine F(1)-C-Ring Complexes of F-ATP Synthase. J.Struct.Biol., 177, 2012
1SYH	X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION. 分子名称: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2 著者 Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S. 登録日 2004-04-01 公開日 2005-03-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2. Mol.Pharmacol., 67, 2005
5QJP	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z1578665941 分子名称: 1,2-ETHANEDIOL, 1-(3-methyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane, ADP-sugar pyrophosphatase, ... 著者 Dubianok, Y, Collins, P, Krojer, T, Wright, N, Strain-Damerell, C, Burgess-Brown, N, Bountra, C, Arrowsmith, C.H, Edwards, A, Huber, K, von Delft, F. 登録日 2018-10-31 公開日 2018-12-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
2RGS	FC-fragment of monoclonal antibody IGG2B from Mus musculus 分子名称: Ig gamma-2B heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Kolenko, P, Duskova, J, Skalova, T, Dohnalek, J, Hasek, J. 登録日 2007-10-05 公開日 2008-10-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2.1-A resolution Immunology, 126, 2008
1HA3	ELONGATION FACTOR TU IN COMPLEX WITH aurodox 分子名称: BETA-MERCAPTOETHANOL, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vogeley, L, Palm, G.J, Mesters, J.R, Hilgenfeld, R. 登録日 2001-03-26 公開日 2001-05-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox J.Biol.Chem., 276, 2001
4IPZ	SmBz bound to Cyclophilin A 分子名称: CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase A, cyclosporine SmBz-CsA 著者 Price, A.J, Jacques, D.A, James, L.C. 登録日 2013-01-10 公開日 2013-11-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 HIV-1 evades innate immune recognition through specific cofactor recruitment. Nature, 503, 2013
7FIM	Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex 分子名称: Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,human glucagon like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. 登録日 2021-07-31 公開日 2022-03-02 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
3NC0	Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II) 分子名称: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
5QE5	PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000632a 分子名称: 1-methyl-5-(phenylamino)-1,2-dihydro-3H-pyrazol-3-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 著者 Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. 登録日 2018-08-30 公開日 2018-10-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.773 Å) 主引用文献 An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018
4IR3	Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (GSK2833282A) 分子名称: 1,2-ETHANEDIOL, 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2B, ... 著者 Chaikuad, A, Felletar, I, Chung, C.W, Drewry, D, Chen, P, Filippakopoulos, P, Fedorov, O, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-01-14 公開日 2013-01-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J.Med.Chem., 59, 2016
4PPH	Crystal structure of conglutin gamma, a unique basic 7S globulin from lupine seeds 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Czubinski, J, Barciszewski, J, Gilski, M, Lampart-Szczapa, E, Jaskolski, M. 登録日 2014-02-27 公開日 2015-02-11 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.009 Å) 主引用文献 Structure of gamma-conglutin: insight into the quaternary structure of 7S basic globulins from legumes. Acta Crystallogr.,Sect.D, 71, 2015
2HIZ	Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor 分子名称: BENZYL [(1S)-2-({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)-2-OXO-1-{[(1-PROPYLBUTYL)SULFONYL]METHYL}ETHYL]CARBAMATE, Beta-secretase 1, PHOSPHATE ION 著者 Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J. 登録日 2006-06-29 公開日 2007-01-23 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Design of potent inhibitors of human beta-secretase. Part 1. Bioorg.Med.Chem.Lett., 17, 2007
4GOG	Crystal structure of the GES-1 imipenem acyl-enzyme complex 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Beta-lactamase GES-1, IODIDE ION, ... 著者 Smith, C.A, Vakulenko, S.B, Munoz, J. 登録日 2012-08-20 公開日 2013-07-24 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural basis for progression toward the carbapenemase activity in the GES family of beta-lactamases. J.Am.Chem.Soc., 134, 2012
1H46	The catalytic module of Cel7D from Phanerochaete chrysosporium as a chiral selector: Structural studies of its complex with the b-blocker (R)-propranolol 分子名称: (1E,2R)-1-(ISOPROPYLIMINO)-3-(1-NAPHTHYLOXY)PROPAN-2-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, EXOGLUCANASE I 著者 Munoz, I.G, Mowbray, S.L, Stahlberg, J. 登録日 2002-10-03 公開日 2003-04-03 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The Catalytic Module of Cel7D from Phanerochaete Chrysosporium as a Chiral Selector: Structural Studies of its Complex with the Beta Blocker (R)-Propranolol Acta Crystallogr.,Sect.D, 59, 2003
3NBE	Clitocybe nebularis ricin B-like lectin (CNL) in complex with N,N'-diacetyllactosediamine 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-2-azidoethyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Ricin B-like lectin, SULFATE ION 著者 Renko, M, Pohleven, J, Sabotic, J, Kos, J, Turk, D. 登録日 2010-06-03 公開日 2011-07-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc beta 1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis J.Biol.Chem., 287, 2012

<1350135113521353135413551356135713581359136013611362136313641365>