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3RZE

Structure of the human histamine H1 receptor in complex with doxepin

Summary for 3RZE
Entry DOI10.2210/pdb3rze/pdb
DescriptorHistamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ... (6 entities in total)
Functional Keywordsstructural genomics, psi-biology, membrane protein, gpcr network, gpcr, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane ; Multi-pass membrane protein : P35367
Total number of polymer chains1
Total formula weight53582.80
Authors
Primary citationShimamura, T.,Shiroishi, M.,Weyand, S.,Tsujimoto, H.,Winter, G.,Katritch, V.,Abagyan, R.,Cherezov, V.,Liu, W.,Han, G.W.,Kobayashi, T.,Stevens, R.C.,Iwata, S.
Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475:65-70, 2011
Cited by
PubMed: 21697825
DOI: 10.1038/nature10236
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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