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4GOV
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BU of 4gov by Molmil
The crystal structure of human fascin 1 S39D mutant
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ...
著者Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
登録日2012-08-20
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
2D9P
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BU of 2d9p by Molmil
Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3
分子名称: Polyadenylate-binding protein 3
著者Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-12
公開日2006-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3
To be Published
2D99
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BU of 2d99 by Molmil
Solution Structure of RSGI RUH-048, a GTF2I domain in human cDNA
分子名称: General transcription factor II-I repeat domain-containing protein 1
著者Doi-Katayama, Y, Hirota, H, Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-09
公開日2006-06-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of RSGI RUH-048, a GTF2I domain in human cDNA
To be Published
2Q8K
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BU of 2q8k by Molmil
The crystal structure of Ebp1
分子名称: GLYCEROL, Proliferation-associated protein 2G4, SULFATE ION
著者Kowalinski, E, Bange, G, Wild, K, Sinning, I.
登録日2007-06-11
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions.
Febs Lett., 581, 2007
2O8F
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BU of 2o8f by Molmil
human MutSalpha (MSH2/MSH6) bound to DNA with a single base T insert
分子名称: 5'-D(*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*CP*GP*TP*C)-3', 5'-D(*GP*AP*CP*GP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
登録日2006-12-12
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2FC0
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BU of 2fc0 by Molmil
WRN exonuclease, Mn dGMP complex
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Werner syndrome helicase
著者Perry, J.J, Tainer, J.A.
登録日2005-12-10
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
2FBY
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BU of 2fby by Molmil
WRN exonuclease, Eu complex
分子名称: EUROPIUM (III) ION, Werner syndrome helicase
著者Perry, J.J.
登録日2005-12-10
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
4KMD
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BU of 4kmd by Molmil
Crystal structure of Sufud60-Gli1p
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Sufu, ...
著者Zhang, Y, Qi, X, Zhang, Z, Wu, G.
登録日2013-05-08
公開日2013-11-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KPW
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Crystal structure of His-tagged human thymidylate synthase R175A mutant
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
著者Pozzi, C, Mangani, S.
登録日2013-05-14
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
J.Med.Chem., 58, 2015
4KM9
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Crystal structure of human Suppressor of Fused
分子名称: Suppressor of fused homolog
著者Zhang, Y, Qi, X, Zhang, Z, Wu, G.
登録日2013-05-08
公開日2013-11-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
2DSD
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BU of 2dsd by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2DWB
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BU of 2dwb by Molmil
Aurora-A kinase complexed with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, Serine/threonine-protein kinase 6
著者Kukimoto-Niino, M, Murayama, K, Shirouzu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-10
公開日2007-07-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aurora-A kinase complexed with AMPPNP
To be Published
4J3I
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BU of 4j3i by Molmil
X-ray crystal structure of bromodomain complex to 1.24 A resolution
分子名称: 1,2-ETHANEDIOL, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxyquinazolin-4(3H)-one, Bromodomain-containing protein 4, ...
著者Stein, A.J, White, A, Suto, R.K.
登録日2013-02-05
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献RVX-208, an Inducer of ApoA-I in Humans, Is a BET Bromodomain Antagonist.
Plos One, 8, 2013
2P9N
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BU of 2p9n by Molmil
Crystal Structure of bovine Arp2/3 complex co-crystallized with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
著者Nolen, B.J, Pollard, T.D.
登録日2007-03-26
公開日2007-05-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2DNY
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BU of 2dny by Molmil
Solution structure of the third RNA binding domain of FBP-interacting repressor, SIAHBP1
分子名称: Fuse-binding protein-interacting repressor, isoform b
著者Suzuki, S, Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-27
公開日2007-04-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the third RNA binding domain of FBP-interacting repressor, SIAHBP1
To be Published
2P4N
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BU of 2p4n by Molmil
Human Monomeric Kinesin (1BG2) and Bovine Tubulin (1JFF) Docked into the 9-Angstrom Cryo-EM Map of Nucleotide-Free Kinesin Complexed to the Microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Sindelar, C.V, Downing, K.H.
登録日2007-03-12
公開日2008-07-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
J.Cell Biol., 177, 2007
4HHZ
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BU of 4hhz by Molmil
Crystal structure of PARP catalytic domain in complex with novel inhibitors
分子名称: N-{(2S)-1-[4-(4-fluorophenyl)-3,6-dihydropyridin-1(2H)-yl]-1-oxopropan-2-yl}-2-[(9aR)-7-oxo-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridin-1-yl]acetamide, Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Liu, Q.F, Chen, T.T, Xu, Y.C.
登録日2012-10-10
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7199 Å)
主引用文献Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors.
J.Med.Chem., 56, 2013
4HL8
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BU of 4hl8 by Molmil
Re-refinement of the vault ribonucleoprotein particle
分子名称: Major vault protein
著者Casanas, A, Querol-Audi, J, Guerra, P, Pous, J, Tanaka, H, Tsukihara, T, Verdaguer, V, Fita, I.
登録日2012-10-16
公開日2013-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach.
Acta Crystallogr.,Sect.D, 69, 2013
2OVJ
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The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Rac GTPase-activating protein 1
著者Shrestha, L, Papagrigoriou, E, Soundararajan, M, Elkins, J, Johansson, C, von Delft, F, Pike, A.C.W, Burgess, N, Turnbull, A, Debreczeni, J, Gorrec, F, Umeano, C, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-02-14
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2F8N
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2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes
分子名称: Core histone macro-H2A.1, Histone 3, H2ba, ...
著者Chakravarthy, S, Luger, K.
登録日2005-12-02
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Nucleosomes containing the histone domain of macroH2A: In vitro possibilities.
To be Published
2P9P
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Crystal Structure of bovine Arp2/3 complex co-crystallized with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
著者Nolen, B.J, Pollard, T.D.
登録日2007-03-26
公開日2007-05-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2FHO
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BU of 2fho by Molmil
NMR solution structure of the human spliceosomal protein complex p14-SF3b155
分子名称: spliceosomal protein SF3b155, spliceosomal protein p14
著者Kuwasako, K, Dohmae, N, Inoue, M, Shirouzu, M, Guntert, P, Seraphin, B, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-26
公開日2006-12-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structure of the human spliceosomal protein complex p14-SF3b155
To be Published
2OO1
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Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3)
分子名称: 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Bromodomain-containing protein 3, ...
著者Filippakopoulos, P, Bullock, A, Papagrigoriou, E, Keates, T, Cooper, C, Smee, C, Ugochukwu, E, Debreczeni, J, von Delft, F, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC)
登録日2007-01-25
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OT1
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Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with naphthol AS-E phosphate, a competitive inhibitor
分子名称: Fructose-bisphosphate aldolase A, N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
著者St-Jean, M, Izard, T, Sygusch, J.
登録日2007-02-07
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with wiskott-Aldrich syndrome protein.
J.Biol.Chem., 282, 2007
2CPR
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Solution structure of the HRDC domain of human Exosome component 10
分子名称: Exosome component 10
著者Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-19
公開日2005-11-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the HRDC domain of human Exosome component 10
To be Published

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