8QQE
 
 | | Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2 | | 分子名称: | Breast cancer type 2 susceptibility protein, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Miron, S, Legrand, P, Zinn-Justin, S. | | 登録日 | 2023-10-04 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.461 Å) | | 主引用文献 | DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.
Nucleic Acids Res., 52, 2024
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7G9J
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102281-001 | | 分子名称: | 1-(3,4-dihydropyrazin-1(2H)-yl)ethan-1-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
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7RGD
 | | HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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8RH1
 | | Trimeric HSV-2F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | | 分子名称: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus.
J.Biomed.Sci., 31, 2024
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7D4D
 | | Structure of L-lysine oxidase precursor in complex with L-lysine (1.24M) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-Lysine alpha-oxidase, LYSINE | | 著者 | Kitagawa, M, Ito, N, Matsumoto, Y, Inagaki, K, Imada, K. | | 登録日 | 2020-09-23 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structural basis of enzyme activity regulation by the propeptide of l-lysine alpha-oxidase precursor from Trichoderma viride .
J Struct Biol X, 5, 2021
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2P4G
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7K3R
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7D4E
 | | Structure of L-lysine oxidase precursor in complex with L-lysine (1.0 M) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-Lysine alpha-oxidase, LYSINE | | 著者 | Kitagawa, M, Ito, N, Matsumoto, Y, Inagaki, K, Imada, K. | | 登録日 | 2020-09-23 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis of enzyme activity regulation by the propeptide of l-lysine alpha-oxidase precursor from Trichoderma viride .
J Struct Biol X, 5, 2021
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7T3I
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5MRW
 | | Structure of the KdpFABC complex | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | | 著者 | Huang, C, Pedersen, B.P, Stokes, D.L. | | 登録日 | 2016-12-27 | | 公開日 | 2017-06-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the potassium-importing KdpFABC membrane complex.
Nature, 546, 2017
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3HMJ
 | | Saccharomyces cerevisiae FAS type I | | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Johansson, P, Mulinacci, B, Koestler, C, Vollrath, R, Oesterhelt, D, Grininger, M. | | 登録日 | 2009-05-29 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
Structure, 17, 2009
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3I35
 | | Human SH3 domain of protein LASP1 | | 分子名称: | LIM and SH3 domain protein 1 | | 著者 | Siponen, M.I, Roos, A.K, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Kragh Nielsen, T, Moche, M, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-06-30 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Human SH3 domain of protein LASP1
TO BE PUBLISHED
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2P4U
 | | Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus | | 分子名称: | Acid phosphatase 1, PHOSPHATE ION | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-03-13 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
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8RGZ
 | | Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | | 分子名称: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus.
J.Biomed.Sci., 31, 2024
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7KCJ
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5MAM
 | | Human insulin in complex with serotonin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. | | 登録日 | 2016-11-03 | | 公開日 | 2017-04-05 | | 最終更新日 | 2017-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
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5MB0
 | | Cocktail experiment A: fragments 63, 267, and 291 in complex with Endothiapepsin | | 分子名称: | 2,5-dimethyl-N-(pyridin-4-yl)furan-3-carboxamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... | | 著者 | Radeva, N, Heine, A, Klebe, G. | | 登録日 | 2016-11-07 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.149 Å) | | 主引用文献 | Comparison of cocktail versus single soaking experimets
To Be Published
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7JSR
 | | Crystal structure of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis | | 分子名称: | NAD-specific glutamate dehydrogenase | | 著者 | Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N. | | 登録日 | 2020-08-15 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (6.27 Å) | | 主引用文献 | 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.
Commun Biol, 4, 2021
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5MC2
 | | Crystal Structure of Gly278Asp mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, MANGANESE (II) ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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8RH2
 | | Trimeric HSV-2G gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules. | | 分子名称: | Envelope glycoprotein B, HDIT102 Fab heavy chain, HDIT102 Fab light chain | | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus.
J.Biomed.Sci., 31, 2024
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7JOF
 | | Calcium-bound C2A Domain from Human Dysferlin | | 分子名称: | CALCIUM ION, Isoform 6 of Dysferlin | | 著者 | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | | 登録日 | 2020-08-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
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3HSN
 | | Ternary structure of neuronal nitric oxide synthase with NHA and CO bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CARBON MONOXIDE, ... | | 著者 | Doukov, T, Li, H, Soltis, M, Poulos, T.L. | | 登録日 | 2009-06-10 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(omega)-hydroxy-L-arginine and diatomic ligands.
Biochemistry, 48, 2009
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7TAD
 | | CryoEM structure of the (NPR1)2-(TGA3)2 complex | | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | | 登録日 | 2021-12-20 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
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7KD7
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8RKU
 | | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsC domain local-refinement map | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target strand - LE, ... | | 著者 | Tenjo-Castano, F, Mesa, P, Montoya, G. | | 登録日 | 2023-12-30 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly.
Mol.Cell, 84, 2024
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