PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4LEK	Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines 分子名称: 7-[5,6-dimethoxy-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hilgers, M.T. 登録日 2013-06-25 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines. J.Med.Chem., 57, 2014
4LF3	Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor 分子名称: Fab heavy chain, Fab light chain, Glucagon receptor 著者 Murray, J.M, Mukund, S. 登録日 2013-06-26 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.735 Å) 主引用文献 Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. J.Biol.Chem., 288, 2013
4LEH	Crystal structure of a bile-acid 7-alpha dehydratase (CLOSCI_03134) from Clostridium scindens ATCC 35704 at 2.90 A resolution 分子名称: Bile acid 7-alpha dehydratase, BaiE, SULFATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-06-25 公開日 2013-08-21 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of a bile-acid 7-alpha dehydratase (CLOSCI_03134) from Clostridium scindens ATCC 35704 at 2.90 A resolution To be published
4EPS	Crystal structure of a fimbrial protein (BACOVA_04982) from Bacteroides ovatus ATCC 8483 at 1.85 A resolution 分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-04-17 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4LAG	Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines 分子名称: 6-chloro-7-[5,6-dimethyl-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hilgers, M.T. 登録日 2013-06-19 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines. J.Med.Chem., 57, 2014
3SEE	Crystal structure of a putative sugar binding protein (BT_4411) from Bacteroides thetaiotaomicron VPI-5482 at 1.25 A resolution 分子名称: Hypothetical sugar binding protein, SODIUM ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-10 公開日 2011-08-03 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of a Hypothetical sugar binding protein (BT_4411) from Bacteroides thetaiotaomicron VPI-5482 at 1.25 A resolution To be published
4EIJ	Structure of the Mumps virus phosphoprotein oligomerization domain 分子名称: GLYCEROL, P protein 著者 Cox, R, Green, T.J, Luo, M. 登録日 2012-04-05 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2001 Å) 主引用文献 Structural and functional characterization of the mumps virus phosphoprotein. J.Virol., 87, 2013
4RH3	AMPPCP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ... 著者 Kloos, M. 登録日 2014-10-01 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
3S25	Crystal structure of a 7-bladed beta-propeller-like protein (EUBREC_1955) from Eubacterium rectale ATCC 33656 at 1.88 A resolution 分子名称: 1,2-ETHANEDIOL, Hypothetical 7-bladed beta-propeller-like protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-05-16 公開日 2011-06-08 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structure of a Hypothetical 7-bladed beta-propeller-like protein (EUBREC_1955, ERE_32420) from Eubacterium rectale at 1.88 A resolution To be published
4EWX	Human Insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. 登録日 2012-04-28 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4EXX	Human Insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. 登録日 2012-05-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4RJV	Crystal Structure of a De Novo Designed Ferredoxin Fold, Northeast Structural Genomics Consortium (NESG) Target OR461 分子名称: OR461 著者 O'Connell, P.T, Lin, Y.-R, Guan, R, Koga, N, Koga, R, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2014-10-09 公開日 2014-10-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.523 Å) 主引用文献 Northeast Structural Genomics Consortium Target OR461 To be published
4L8O	Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from Clostridium hylemonae DSM 15053 at 2.20 A resolution 分子名称: 1,2-ETHANEDIOL, Bile acid 7a-dehydratase, BaiE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-06-17 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from Clostridium hylemonae DSM 15053 at 2.20 A resolution To be published
4ROJ	Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide 分子名称: Guanine nucleotide exchange factor VAV2, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-10-28 公開日 2014-12-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide TO BE PUBLISHED
4L9R	Crystal Structure of apo A12K/D35S mutant myo-inositol dehydrogenase from Bacillus subtilis 分子名称: Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 著者 Bertwistle, D, Sanders, D.A.R, Palmer, D.R.J. 登録日 2013-06-18 公開日 2013-09-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist. Biochemistry, 52, 2013
4RPJ	Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with UDP 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase, URIDINE-5'-DIPHOSPHATE 著者 Van Straaten, K.E, Sanders, D.A.R. 登録日 2014-10-30 公開日 2015-01-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues. J.Am.Chem.Soc., 137, 2015
4E6R	Crystal structure of a Cytoplasmic protein NCK2 (NCK2) from Homo sapiens at 2.20 A resolution 分子名称: Cytoplasmic protein NCK2, IMIDAZOLE, UNKNOWN LIGAND, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-03-15 公開日 2012-04-04 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a Cytoplasmic protein NCK2 (NCK2) from Homo sapiens at 2.20 A resolution To be published
4RKP	Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (apo form) 分子名称: ACETATE ION, Putative uncharacterized protein Ta1305, SULFATE ION 著者 Vinokur, J.M, Cascio, D, Sawaya, M.R, Bowie, J.U. 登録日 2014-10-13 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci., 24, 2015
4L3U	Crystal structure of a DUF3571 family protein (ABAYE3784) from Acinetobacter baumannii AYE at 1.95 A resolution 分子名称: CHLORIDE ION, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-06-06 公開日 2013-07-31 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of a hypothetical protein (ABAYE3784) from Acinetobacter baumannii AYE at 1.95 A resolution To be published
3SCY	Crystal structure of a putative 6-phosphogluconolactonase (BF1038) from Bacteroides fragilis NCTC 9343 at 1.50 A resolution 分子名称: Hypothetical bacterial 6-phosphogluconolactonase, MAGNESIUM ION, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-08 公開日 2011-07-20 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a Hypothetical bacterial 6-phosphogluconolactonase (BF1038) from Bacteroides fragilis NCTC 9343 at 1.50 A resolution To be published
4RZT	Lac repressor engineered to bind sucralose, sucralose-bound tetramer 分子名称: 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Lac repressor 著者 Arbing, M.A, Cascio, D, Sawaya, M.R, Kosuri, S, Church, G.M. 登録日 2014-12-24 公開日 2015-12-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13, 2016
4EY1	Human Insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. 登録日 2012-05-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.471 Å) 主引用文献 Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4EIU	Crystal structure of a DUF3823 family protein (BACUNI_03093) from Bacteroides uniformis ATCC 8492 at 1.90 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, uncharacterized hypothetical protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-04-05 公開日 2012-05-30 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a hypothetical protein (BACUNI_03093) from Bacteroides uniformis ATCC 8492 at 1.90 A resolution To be published
4Q9U	Crystal structure of the Rab5, Rabex-5delta and Rabaptin-5C21 complex 分子名称: Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A 著者 Zhang, Z, Zhang, T, Ding, J. 登録日 2014-05-01 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.618 Å) 主引用文献 Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5 Elife, 3, 2014
4QAG	Structure of a dihydroxycoumarin active-site inhibitor in complex with the RNASE H domain of HIV-1 reverse transcriptase 分子名称: (7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H 著者 Himmel, D.M, Ho, W.C, Arnold, E. 登録日 2014-05-04 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.712 Å) 主引用文献 Structure of a Dihydroxycoumarin Active-Site Inhibitor in Complex with the RNase H Domain of HIV-1 Reverse Transcriptase and Structure-Activity Analysis of Inhibitor Analogs. J.Mol.Biol., 426, 2014

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