4Q9U

Crystal structure of the Rab5, Rabex-5delta and Rabaptin-5C21 complex

Summary for 4Q9U

• Entry DOI: 10.2210/pdb4q9u/pdb
• Related: 4N3X 4N3Y 4N3Z
• Descriptor: Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A, Rab GTPase-binding effector protein 1 (3 entities in total)
• Functional Keywords: rab5, rabex-5, rabaptin-5, gef activity, endocytosis, early endosomes, vps9, coiled-coil, gef, effector, small gtpases
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q9UJ41 Q15276; Cell membrane ; Lipid-anchor ; Cytoplasmic side : P20339
• Total number of polymer chains: 8
• Total formula weight: 155595.35

Authors

Zhang, Z.,Zhang, T.,Ding, J. (deposition date: 2014-05-01, release date: 2014-07-23, Last modification date: 2023-11-08)

• Primary citation: Zhang, Z.,Zhang, T.,Wang, S.,Gong, Z.,Tang, C.,Chen, J.,Ding, J.; Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5; Elife, 3:e02687-e02687, 2014; PubMed: 24957337; DOI: 10.7554/eLife.02687

Experimental method

X-RAY DIFFRACTION (4.618 Å)