7QH8
| CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE | 分子名称: | GLYCEROL, LYSINE, Lysine--tRNA ligase 1 | 著者 | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | 登録日 | 2021-12-10 | 公開日 | 2022-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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2YOL
| West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA | 分子名称: | (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ... | 著者 | Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T. | 登録日 | 2012-10-25 | 公開日 | 2013-03-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease. Chemmedchem, 8, 2013
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7T76
| HIV-1 Envelope ApexGT3 in complex with PG9.iGL Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT3 gp120, ... | 著者 | Berndsen, Z.T, Ward, A.B. | 登録日 | 2021-12-14 | 公開日 | 2022-09-28 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | 主引用文献 | Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors. Immunity, 55, 2022
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7M17
| SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1) | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A | 著者 | Kern, D.M, Gerber, E.E, Brohawn, S.G. | 登録日 | 2021-03-12 | 公開日 | 2021-03-24 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Nat Commun, 13, 2022
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7T77
| HIV-1 Envelope ApexGT3.N130 in complex with PG9 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT3.N130 gp120, ... | 著者 | Berndsen, Z.T, Ward, A.B. | 登録日 | 2021-12-14 | 公開日 | 2022-09-28 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (4.75 Å) | 主引用文献 | Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors. Immunity, 55, 2022
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5MQQ
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3K4X
| Eukaryotic Sliding Clamp PCNA Bound to DNA | 分子名称: | DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen | 著者 | McNally, R, Kuriyan, J. | 登録日 | 2009-10-06 | 公開日 | 2010-02-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Struct.Biol., 10, 2010
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5MXH
| Photorhabdus asymbiotica lectin (PHL) in complex with D-galactose | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Photorhabdus asymbiotica lectin PHL, ... | 著者 | Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. | 登録日 | 2017-01-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
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3K5P
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7SQX
| Crystal Structure of Pseudomonas aeruginosa lytic polysaccharide monooxygenase CbpD | 分子名称: | AMMONIUM ION, Chitin-binding protein CbpD | 著者 | Dade, C, Douzi, B, Ball, G, Voulhoux, R, Forest, K.T. | 登録日 | 2021-11-07 | 公開日 | 2022-07-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases. Acta Crystallogr D Struct Biol, 78, 2022
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2JDF
| Human gamma-B crystallin | 分子名称: | GAMMA CRYSTALLIN B | 著者 | Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U. | 登録日 | 2007-01-08 | 公開日 | 2007-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein. J.Mol.Biol., 372, 2007
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7T73
| HIV-1 Envelope ApexGT2.2MUT in complex with PCT64.LMCA Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT2.2MUT gp120, ... | 著者 | Berndsen, Z.T, Ward, A.B. | 登録日 | 2021-12-14 | 公開日 | 2022-09-28 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors. Immunity, 55, 2022
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5MR6
| XiaF from Streptomyces sp. in complex with FADH2 and Glycerol | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, XiaF protein | 著者 | Kugel, S, Baunach, M, Baer, P, Ishida-Ito, M, Sundaram, S, Xu, Z, Groll, M, Hertweck, C. | 登録日 | 2016-12-21 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun, 8, 2017
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6ZLO
| E2 core of the fungal Pyruvate dehydrogenase complex with asymmetric interior PX30 component | 分子名称: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 著者 | Forsberg, B.O, Howard, R.J, Aibara, S, Mortesaei, N, Lindahl, E. | 登録日 | 2020-06-30 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex. Nat Commun, 11, 2020
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3J8X
| High-resolution structure of no-nucleotide kinesin on microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | 著者 | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | 登録日 | 2014-11-20 | 公開日 | 2014-12-10 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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6ZNP
| Crystal Structure of DUF1998 helicase MrfA bound to DNA | 分子名称: | CITRIC ACID, Uncharacterized ATP-dependent helicase YprA, ZINC ION, ... | 著者 | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | 登録日 | 2020-07-06 | 公開日 | 2020-11-25 | 最終更新日 | 2021-01-20 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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8QQS
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3J93
| Fitting of Fab into the cryoEM density map of EV71 procapsid in complex with Fab22A12 | 分子名称: | neutralizing antibody 22A12, heavy chain, light chain | 著者 | Shingler, K.L, Cifuente, J.O, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S. | 登録日 | 2014-12-02 | 公開日 | 2014-12-24 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | 主引用文献 | The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro. J.Virol., 89, 2015
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6ZNQ
| Crystal Structure of DUF1998 helicase MrfA bound to DNA and AMPPNP | 分子名称: | CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Uncharacterized ATP-dependent helicase YprA, ... | 著者 | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | 登録日 | 2020-07-06 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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5MTQ
| Crystal structure of M. tuberculosis InhA inhibited by PT511 | 分子名称: | 2-[4-[(4-cyclohexyl-1,2,3-triazol-1-yl)methyl]-2-oxidanyl-phenoxy]benzenecarbonitrile, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. | 登録日 | 2017-01-10 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017
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3J98
| Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) | 分子名称: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | 著者 | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | 登録日 | 2014-12-05 | 公開日 | 2015-01-28 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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5M5S
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7SVL
| DPP9 IN COMPLEX WITH LIGAND ICeD-2 | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 9 | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | 登録日 | 2021-11-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7M19
| SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-2) | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A | 著者 | Kern, D.M, Gerber, E.E, Brohawn, S.G. | 登録日 | 2021-03-12 | 公開日 | 2021-03-24 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Nat Commun, 13, 2022
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3J9Q
| Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states | 分子名称: | sheath, tube | 著者 | Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H. | 登録日 | 2015-02-17 | 公開日 | 2015-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states. Nat.Struct.Mol.Biol., 22, 2015
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