PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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5LWD	Thermolysin in complex with inhibitor (JC96) 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Krimmer, S.G, Cramer, J, Heine, A, Klebe, G. 登録日 2016-09-15 公開日 2016-12-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin. ACS Chem. Biol., 12, 2017
3JPN	Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dichloro methylene triphosphate 分子名称: 2'-deoxy-5'-O-[(S)-{[(R)-[dichloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... 著者 Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E. 登録日 2009-09-04 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues. J.Am.Chem.Soc., 132, 2010
3JPR	Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dimethyl methylene triphosphate 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(1-methyl-1-phosphonoethyl)phosphoryl]oxy}phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... 著者 Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E. 登録日 2009-09-04 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues. J.Am.Chem.Soc., 132, 2010
7U3H	GID4 in complex with compound 7 分子名称: (5R)-N-(4-fluorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine, Glucose-induced degradation protein 4 homolog 著者 Chana, C.K, Sicheri, F. 登録日 2022-02-27 公開日 2022-10-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J.Med.Chem., 65, 2022
2FUC	Human alpha-Phosphomannomutase 1 with Mg2+ cofactor bound 分子名称: MAGNESIUM ION, Phosphomannomutase 1 著者 Silvaggi, N.R, Zhang, C, Lu, Z, Dunaway-Mariano, D, Allen, K.N. 登録日 2006-01-26 公開日 2006-03-21 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a. J.Biol.Chem., 281, 2006
2MOQ	Solution Structure and Molecular determinants of Hemoglobin Binding of the first NEAT Domain of IsdB in Staphylococcus aureus 分子名称: Iron-regulated surface determinant protein B 著者 Fonner, B.A, Tripet, B.P, Eilers, B.J, Stanisich, J, Sullivan-Springhetti, R.K, Moore, R, Lui, M, Lei, B, Copie, V. 登録日 2014-04-29 公開日 2014-07-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus. Biochemistry, 53, 2014
6ZY4	Cryo-EM structure of MlaFEDB in complex with ADP 分子名称: ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Dong, C.J, Dong, H.H. 登録日 2020-07-30 公開日 2020-11-25 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB. Nat.Struct.Mol.Biol., 28, 2021
5LV2	Crystal structure of mouse CARM1 in complex with inhibitor LH1246 分子名称: 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... 著者 Cura, V, Marechal, N, Troffer-Charlier, N, Halby, L, Arimondo, P, Bonnefond, L, Cavarelli, J. 登録日 2016-09-12 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors. Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
3ANS	Human soluble epoxide hydrolase in complex with a synthetic inhibitor 分子名称: 4-cyano-N-[(1S,2R)-2-phenylcyclopropyl]benzamide, Epoxide hydrolase 2 著者 Chiyo, N, Ishii, T, Hourai, S, Yanagi, K. 登録日 2010-09-08 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A practical use of ligand efficiency indices out of the fragment-based approach: ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors J.Med.Chem., 54, 2011
6ZZ6	Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (34-MER), MAGNESIUM ION, ... 著者 Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Nasmyth, K.A, Lowe, J. 登録日 2020-08-04 公開日 2020-09-30 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3. Elife, 9, 2020
7LVH	CRYSTAL STRUCTURE OF AP2 ASSOCIATED KINASE 1 ISOFORM 1 COMPLEXED WITH LIGAND N-[3-METHOXY-4-(1,3-OXAZOL-5-YL)PHENYL]-3-(PROPAN-2-YL)PIPERIDINE-2-CARBOXAMIDE 分子名称: 5-[(4-aminopiperidin-1-yl)methyl]-N-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine, AP2-associated protein kinase 1, N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-D-leucinamide, ... 著者 Muckelbauer, J.K. 登録日 2021-02-25 公開日 2021-07-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain. J.Med.Chem., 64, 2021
7TZ8	Solution NMR structure of the PBS linker polypeptide domain (fragment 254-400) of phycobilisome linker protein ApcE from Synechocystis sp. PCC 6803 refined with NH RDCs. Northeast Structural Genomics Consortium Target SgR209C 分子名称: Phycobiliprotein ApcE 著者 Ramelot, T.A, Tejero, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2022-02-15 公開日 2022-08-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 AlphaFold Models of Small Proteins Rival the Accuracy of Solution NMR Structures. Front Mol Biosci, 9, 2022
8R1F	Monomeric E6AP-E6-p53 ternary complex 分子名称: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... 著者 Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. 登録日 2023-11-01 公開日 2023-12-06 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
2MQP	Structural Investigation of hnRNP L bound to RNA 分子名称: Protein Hnrnpl, RNA (5'-R(*AP*CP*AP*CP*AP*C)-3') 著者 Blatter, M, Allain, F. 登録日 2014-06-24 公開日 2015-12-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Investigation of hnRNP L bound to RNA To be Published
2MU7	Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria 分子名称: 1513 MSP-1 peptide 著者 Espejo, F, Bermudez, A, Torres, E, Urquiza, M, Rodriguez, R, Lopez, Y, Patarroyo, M. 登録日 2014-09-04 公開日 2014-11-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria. Biochem.Biophys.Res.Commun., 315, 2004
3JT7	Structure of neuronal nitric oxide synthase heme domain complexed with N~5~-[2-(propylsulfanyl)ethanimidoyl]-L-ornithine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, Nitric oxide synthase, ... 著者 Li, H, Poulos, T.L. 登録日 2009-09-11 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency. J.Am.Chem.Soc., 132, 2010
2FYN	Crystal Structure Analysis of the double mutant Rhodobacter Sphaeroides bc1 complex 分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, Cytochrome b, Cytochrome c1, ... 著者 Esser, L, Xia, D. 登録日 2006-02-08 公開日 2006-08-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex. Proc.Natl.Acad.Sci.Usa, 103, 2006
3JSE	Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator 分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta 著者 Stadtmueller, B.M, Whitby, F.G, Hill, C.P. 登録日 2009-09-10 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural models for interactions between the 20S proteasome and its PAN/19S activators. J.Biol.Chem., 285, 2010
7TIT	Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C 分子名称: Myosin-binding protein C, cardiac-type, cardiac actin, ... 著者 Risi, C.M, Galkin, V.E. 登録日 2022-01-14 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022
7QIR	CRYSTAL STRUCTURE OF THE P1 monofluorethylglycine(MfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
2MWG	Full-Length Solution Structure Of YtvA, a LOV-Photoreceptor Protein and Regulator of Bacterial Stress Response 分子名称: Blue-light photoreceptor, FLAVIN MONONUCLEOTIDE 著者 Jurk, M, Bardiaux, B, Schmieder, P. 登録日 2014-11-07 公開日 2016-05-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of YtvA from Bacillus subtilis Provides Insight into Activation Mechanism and Regulation of Bacterial Stress Response. To be Published
5M2Y	Structure of TssK C-terminal domain from E. coli T6SS 分子名称: TssK C 著者 Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A, Legrand, P. 登録日 2016-10-13 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
6ZLT	Open-open state of the Bt1762-Bt1763 levan transport system 分子名称: SusC homolog, SusD homolog 著者 White, J.B.R, van den Berg, B, Ranson, N.A. 登録日 2020-07-01 公開日 2020-11-11 最終更新日 2021-01-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Insights into SusCD-mediated glycan import by a prominent gut symbiont. Nat Commun, 12, 2021
2YBR	Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann 分子名称: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G 著者 Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A. 登録日 2011-03-09 公開日 2011-04-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment J.Biol.Chem., 286, 2011
2YBM	Nitrate X-ray induced reduction on HEWL crystals (23.3 MGy) 分子名称: LYSOZYME C, NITRIC OXIDE 著者 De la Mora, E, Carmichael, I, Garman, E.F. 登録日 2011-03-08 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals. J.Synchrotron.Radiat., 18, 2011

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