PDB: 224572 件ウェブページステータス検索Chemie searchBIRD

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2BR7	Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SOLUBLE ACETYLCHOLINE RECEPTOR 著者 Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, Van Nierop, P, Van Elk, R, Van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. 登録日 2005-05-03 公開日 2005-06-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha- Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
2BR8	Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with an alpha-conotoxin PnIA variant 分子名称: ALPHA-CONOTOXIN PNIA, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION 著者 Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, van Nierop, P, van Elk, R, van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. 登録日 2005-05-03 公開日 2005-06-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha-Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
2BR9	14-3-3 Protein Epsilon (Human) Complexed to Peptide 分子名称: 14-3-3 PROTEIN EPSILON, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS 著者 Yang, X, Elkins, J.M, Soundararajan, M, Fedorov, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A. 登録日 2005-05-03 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family. Proc.Natl.Acad.Sci.USA, 103, 2006
2BRA	Structure of N-Terminal FAD Binding motif of mouse MICAL 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS 著者 Nadella, M, Bianchet, M.A, Gabelli, S.B, Amzel, L.M. 登録日 2005-05-04 公開日 2005-11-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and activity of the axon guidance protein MICAL. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
2BRB	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-04 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRC	Structure of a Hsp90 Inhibitor bound to the N-terminus of Yeast Hsp90. 分子名称: 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Roe, S.M, Pearl, L.H, Prodromou, C. 登録日 2005-05-04 公開日 2005-09-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg. Med. Chem. Lett., 15, 2005
2BRD	CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE 分子名称: BACTERIORHODOPSIN, PHOSPHORIC ACID 2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL ESTER 2-HYDROXO-3-PHOSPHONOOXY-PROPYL ESTER, RETINAL 著者 Henderson, R, Grigorieff, N. 登録日 1995-12-27 公開日 1996-06-10 最終更新日 2024-06-05 実験手法 ELECTRON CRYSTALLOGRAPHY (3.5 Å) 主引用文献 Electron-crystallographic refinement of the structure of bacteriorhodopsin. J.Mol.Biol., 259, 1996
2BRE	STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90. 分子名称: 4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Roe, S.M, Pearl, L.H, Prodromou, C. 登録日 2005-05-04 公開日 2005-09-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg. Med. Chem. Lett., 15, 2005
2BRF	Crystal Structure of the FHA Domain of Human Polynucleotide Kinase 3' Phosphatase 分子名称: BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, SULFATE ION 著者 Oliver, A.W, Ali, A.A.E, Pearl, L.H. 登録日 2005-05-04 公開日 2005-05-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk. Nucleic Acids Res., 37, 2009
2BRG	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: (5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC, SERINE/THREONINE-PROTEIN KINASE CHK1 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-05 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRH	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE, SERINE/THREONINE-PROTEIN KINASE CHK1 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-05 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRI	UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH ITS SUBSTRATE ANALOG AMPPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, URIDYLATE KINASE 著者 Marco-Marin, C, Gil-Ortiz, F, Rubio, V. 登録日 2005-05-05 公開日 2005-07-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Crystal Structure of Pyrococcus Furiosus Ump Kinase Provides Insight Into Catalysis and Regulation in Microbial Pyrimidine Nucleotide Biosynthesis. J.Mol.Biol., 352, 2005
2BRJ	X-ray structure of the Allene Oxide Cyclase from Arabidopsis thaliana 分子名称: ARABIDOPSIS THALIANA GENOMIC DNA, CHROMOSOME 3,, GLYCEROL 著者 Hofmann, E, Zerbe, P, Schaller, F. 登録日 2005-05-06 公開日 2006-08-24 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Crystal Structure of Arabidopsis Thaliana Allene Oxide Cyclase: Insights Into the Oxylipin Cyclization Reaction. Plant Cell, 18, 2006
2BRK	Crystal structure of Hepatitis C virus polymerase in complex with an allosteric inhibitor (compound 1) 分子名称: 3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Di Marco, S, Volpari, C, Carfi, A. 登録日 2005-05-06 公開日 2005-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small-Molecule Inhibitors Bound to a Novel Allosteric Site J.Biol.Chem., 280, 2005
2BRL	Crystal structure of Hepatitis C virus polymerase in complex with an allosteric inhibitor (compound 2) 分子名称: 3-CYCLOHEXYL-1-(2-{METHYL[(1-METHYLPIPERIDIN-3-YL)METHYL]AMINO}-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Di Marco, S, Volpari, C, Carfi, A. 登録日 2005-05-06 公開日 2005-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small-Molecule Inhibitors Bound to a Novel Allosteric Site J.Biol.Chem., 280, 2005
2BRM	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: 3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-09 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRN	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: (2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL, SERINE/THREONINE-PROTEIN KINASE CHK1 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-09 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRO	Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity 分子名称: (2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL, SERINE/THREONINE-PROTEIN KINASE CHK1 著者 Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. 登録日 2005-05-09 公開日 2005-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
2BRP	Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b 分子名称: D-xylose, HYALURONATE LYASE, SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER, ... 著者 Rigden, D.J, Jedrzejas, M.J. 登録日 2005-05-10 公開日 2006-04-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology, 16, 2006
2BRQ	Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide 分子名称: FILAMIN A, GLUTATHIONE, GLYCEROL, ... 著者 Kiema, T.-R, Ylanne, J. 登録日 2005-05-11 公開日 2006-02-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Molecular Basis of Filamin Binding to Integrins and Competition with Talin. Mol.Cell, 21, 2006
2BRR	Complex of the neisserial PorA P1.4 epitope peptide and two Fab- fragments (antibody MN20B9.34) 分子名称: ACETIC ACID, CLASS 1 OUTER MEMBRANE PROTEIN VARIABLE REGION 2, MN20B9.34 ANTI-P1.4 ANTIBODY, ... 著者 Oomen, C.J, Hoogerhout, P, Kuipers, B, Vidarsson, G, Van Alphen, L, Gros, P. 登録日 2005-05-11 公開日 2005-07-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of an Anti-Meningococcal Subtype P1.4 Pora Antibody Provides Basis for Peptide- Vaccine Design. J.Mol.Biol., 351, 2005
2BRS	EMBP Heparin complex 分子名称: 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, EOSINOPHIL-GRANULE MAJOR BASIC PROTEIN, SULFATE ION 著者 Swaminathan, G.J, Myszka, D.G, Katsamba, P.S, Ohnuki, L.E, Gleich, G.J, Acharya, K.R. 登録日 2005-05-11 公開日 2005-10-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Eosinophil-Granule Major Basic Protein, a C-Type Lectin, Binds Heparin Biochemistry, 44, 2005
2BRT	ANTHOCYANIDIN SYNTHASE FROM ARABIDOPSIS THALIANA COMPLEXED with naringenin 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, LEUCOANTHOCYANIDIN DIOXYGENASE, ... 著者 Turnbull, J.J, Clifton, I.J, Welford, R.W.D, Schofield, C.J. 登録日 2005-05-11 公開日 2006-08-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Mechanistic Studies on Anthocyanidin Synthase Catalysed Oxidation of Flavanone Substrates: The Effect of C-2 Stereochemistry on Product Selectivity and Mechanism Org.Biomol.Chem., 3, 2005
2BRU	Complex of the domain I and domain III of Escherichia coli transhydrogenase 分子名称: NAD(P) TRANSHYDROGENASE SUBUNIT ALPHA, NAD(P) TRANSHYDROGENASE SUBUNIT BETA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Johansson, T, Pedersen, A, Leckner, J, Karlsson, B.G. 登録日 2005-05-11 公開日 2006-08-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure Determination of a Transient Complex by NMR Using Paramagnetic Distance Restraints - the Complex of the Soluble Domains of Escherichia Coli Transhydrogenase To be Published
2BRV	Crystal structure of Streptococcus Pneumoniae Hyaluronate Lyase from 70percent saturated malonate. 分子名称: HYALURONATE LYASE, MALONIC ACID 著者 Rigden, D.J, Jedrzejas, M.J. 登録日 2005-05-11 公開日 2006-04-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action. J.Mol.Biol., 358, 2006

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