2BRP

Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b

Summary for 2BRP

Entry DOI	10.2210/pdb2brp/pdb
Related	1C82 1EGU 1F9G 1LOH 1LXK 1N7N 1N7O 1N7P 1N7Q 1N7R 1OJM 1OJN 1OJO 1OJP 1W3Y 2BRV 2BRW
Descriptor	HYALURONATE LYASE, SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER, D-xylose, ... (5 entities in total)
Functional Keywords	(alfa5/alfa5) barrel, lyase, peptidoglycan-anchor
Biological source	STREPTOCOCCUS PNEUMONIAE
Total number of polymer chains	1
Total formula weight	85016.31
Authors	Rigden, D.J.,Jedrzejas, M.J. (deposition date: 2005-05-10, release date: 2006-04-24, Last modification date: 2023-12-13)
Primary citation	Rigden, D.J.,Botzki, A.,Nukui, M.,Mewbourne, R.B.,Lamani, E.,Braun, S.,von Angerer, E.,Bernhardt, G.,Dove, S.,Buschauer, A.,Jedrzejas, M.J. Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology, 16:757-765, 2006 Cited by PubMed: 16638841 DOI: 10.1093/glycob/cwj116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation