2BRP
Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HYALURONATE LYASE | polymer | 731 | 83561.9 | 1 | UniProt (Q54873) Pfam (PF08124) Pfam (PF02278) Pfam (PF02884) | STREPTOCOCCUS PNEUMONIAE | HYALURONIDASE, HYASE |
| 2 | B (A) | SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER | non-polymer | 523.7 | 1 | Chemie (SIE) PubChem (6540269) | |||
| 3 | C, D, E (A) | D-xylose | non-polymer | 150.1 | 3 | Chemie (XLS) PubChem (854) PubChem (8985) PubChem (65550) PubChem (66308) PubChem (90428) PubChem (95259) PubChem (25244114) PubChem (644160) PubChem (644176) PubChem (57557845) PubChem (58332771) PubChem (5311110) PubChem (89052457) PubChem (12306953) PubChem (12306954) PubChem (5460291) PubChem (130831430) PubChem (135055741) | |||
| 4 | F, G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | K (A) | water | water | 18.0 | 560 | Chemie (HOH) |
Sequence modifications
A: 168 - 892 (UniProt: Q54873)
A: 893 - 898 (PDB: 2BRP)
| PDB | External Database | Details |
|---|---|---|
| Thr 173 | Ala 290 | conflict |
| Asp 196 | Glu 313 | conflict |
| Ile 223 | Thr 340 | conflict |
| Arg 496 | Cys 613 | conflict |
| Thr 541 | Pro 658 | conflict |
| Ser 704 | Gly 821 | conflict |
| Ser 736 | Phe 853 | conflict |
| Gly 790 | Arg 907 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 83561.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1454.4 | |
| All* | Total formula weight | 85016.3 |
