2BRP
Crystal structure of S. pneumoniae hyaluronate lyase in complex with W249b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HYALURONATE LYASE | polymer | 731 | 83561.9 | 1 | UniProt (Q54873) Pfam (PF08124) Pfam (PF02278) Pfam (PF02884) | STREPTOCOCCUS PNEUMONIAE | HYALURONIDASE, HYASE |
| 2 | B (A) | SULFAMIC ACID 1-DECYL-2-(4-SULFAMOYLOXYPHENYL)-1H-INDOL-6-YL ESTER | non-polymer | 523.7 | 1 | Chemie (SIE) | |||
| 3 | C, D, E (A) | D-xylose | non-polymer | 150.1 | 3 | Chemie (XLS) | |||
| 4 | F, G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | K (A) | water | water | 18.0 | 560 | Chemie (HOH) |
Sequence modifications
A: 168 - 892 (UniProt: Q54873)
A: 893 - 898 (PDB: 2BRP)
| PDB | External Database | Details |
|---|---|---|
| Thr 173 | Ala 290 | conflict |
| Asp 196 | Glu 313 | conflict |
| Ile 223 | Thr 340 | conflict |
| Arg 496 | Cys 613 | conflict |
| Thr 541 | Pro 658 | conflict |
| Ser 704 | Gly 821 | conflict |
| Ser 736 | Phe 853 | conflict |
| Gly 790 | Arg 907 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 83561.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1454.4 | |
| All* | Total formula weight | 85016.3 |
