2BRF

Crystal Structure of the FHA Domain of Human Polynucleotide Kinase 3' Phosphatase

Summary for 2BRF

Entry DOI	10.2210/pdb2brf/pdb
Descriptor	BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, SULFATE ION (3 entities in total)
Functional Keywords	hydrolase/transferase, fha, forkhead-associated, pnkp, pnk, polynucleotide kinase 3' phosphatase, dna repair, ber, ssbr, dsbr, xrcc1, xrcc4 hydrolase, transferase, bifunctional, hydrolase-transferase complex
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: Q96T60
Total number of polymer chains	1
Total formula weight	12001.48
Authors	Oliver, A.W.,Ali, A.A.E.,Pearl, L.H. (deposition date: 2005-05-04, release date: 2005-05-09, Last modification date: 2023-12-13)
Primary citation	Ali, A.A.E.,Jukes, R.M.,Pearl, L.H.,Oliver, A.W. Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk. Nucleic Acids Res., 37:1701-, 2009 Cited by PubMed: 19155274 DOI: 10.1093/NAR/GKN1086 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation