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6W5N
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BU of 6w5n by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6W5M
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BU of 6w5m by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6YTO
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BU of 6yto by Molmil
Cryo-EM structure of a dimer of decameric human CALHM4 in the presence of Ca2+
分子名称: Calcium homeostasis modulator protein 4
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
6Z2J
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BU of 6z2j by Molmil
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-05-16
公開日2020-07-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
6YTK
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BU of 6ytk by Molmil
Cryo-EM structure of a dimer of decameric human CALHM4 in the absence of Ca2+
分子名称: Calcium homeostasis modulator protein 4
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
6YTX
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BU of 6ytx by Molmil
Cryo-EM structure of undecameric human CALHM6 in the presence of Ca2+
分子名称: Calcium homeostasis modulator protein 6
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (6.23 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
6YTQ
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BU of 6ytq by Molmil
Cryo-EM structure of a dimer of undecameric human CALHM4 in the presence of Ca2+
分子名称: Calcium homeostasis modulator protein 4
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
1EOT
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BU of 1eot by Molmil
SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE
分子名称: EOTAXIN
著者Crump, M.P, Rajarathnam, K, Sykes, B.D.
登録日1998-06-17
公開日1999-01-13
最終更新日2024-11-20
実験手法SOLUTION NMR
主引用文献Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
6YTL
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BU of 6ytl by Molmil
Cryo-EM structure of a dimer of undecameric human CALHM4 in the absence of Ca2+
分子名称: Calcium homeostasis modulator protein 4
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
6YTV
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BU of 6ytv by Molmil
Cryo-EM structure of decameric human CALHM6 in the presence of Ca2+
分子名称: Calcium homeostasis modulator protein 6
著者Sawicka, M, Drozdzyk, K, Dutzler, R.
登録日2020-04-24
公開日2020-05-13
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (4.39 Å)
主引用文献Cryo-EM structures and functional properties of CALHM channels of the human placenta.
Elife, 9, 2020
8BE0
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BU of 8be0 by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-20
公開日2022-12-28
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BDR
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BU of 8bdr by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-19
公開日2022-12-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BEK
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BU of 8bek by Molmil
Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-21
公開日2022-12-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
6Z2K
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BU of 6z2k by Molmil
The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-05-16
公開日2020-07-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
8SIY
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BU of 8siy by Molmil
Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome
分子名称: Histone H2A, Histone H2B, Histone H3.2, ...
著者Bleichert, F, Ekundayo, B.E.
登録日2023-04-17
公開日2023-08-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin.
Embo J., 42, 2023
4YFU
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BU of 4yfu by Molmil
Crystal structure of open Bacillus fragment DNA polymerase bound to DNA and dTTP
分子名称: DNA polymerase, Primer DNA, SULFATE ION, ...
著者Wu, E.Y.
登録日2015-02-25
公開日2015-07-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Closing Mechanism of DNA Polymerase I at Atomic Resolution.
Structure, 23, 2015
4FYK
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BU of 4fyk by Molmil
Crystal structure of rcl with 5'-phiosphorothioate-adenosine
分子名称: ADENOSINE -5'-THIO-MONOPHOSPHATE, Deoxyribonucleoside 5'-monophosphate N-glycosidase, SULFATE ION
著者Labesse, G, Padilla, A, Kaminski, P.A.
登録日2012-07-04
公開日2013-01-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure of the oncoprotein Rcl bound to three nucleotide analogues.
Acta Crystallogr.,Sect.D, 69, 2013
8G86
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BU of 8g86 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome)
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
1FKX
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BU of 1fkx by Molmil
MURINE ADENOSINE DEAMINASE (D296A)
分子名称: 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1996-02-29
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
Biochemistry, 35, 1996
4FYH
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BU of 4fyh by Molmil
Crystal structure of rcl with phospho-triciribine
分子名称: 5-methyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine, Deoxyribonucleoside 5'-monophosphate N-glycosidase, SULFATE ION
著者Labesse, G, Padilla, A, Kaminski, P.A.
登録日2012-07-04
公開日2013-01-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure of the oncoprotein Rcl bound to three nucleotide analogues.
Acta Crystallogr.,Sect.D, 69, 2013
3VAQ
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BU of 3vaq by Molmil
Adenosine kinase from Schistosoma mansoni in complex with adenosine
分子名称: ADENOSINE, CHLORIDE ION, Putative adenosine kinase
著者Romanello, L, Bachega, F.R, Garatt, R.C, DeMarco, R, Pereira, H.M.
登録日2011-12-29
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues.
Acta Crystallogr.,Sect.D, 69, 2013
3UQ9
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BU of 3uq9 by Molmil
Adenosine kinase from Schistosoma mansoni in complex with tubercidin
分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Adenosine kinase, putative, ...
著者Romanello, L, Cassago, A, Bachega, F.R, Garatt, R.C, DeMarco, R, Pereira, H.M.
登録日2011-11-19
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.343 Å)
主引用文献Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues.
Acta Crystallogr.,Sect.D, 69, 2013
6YQQ
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BU of 6yqq by Molmil
ForT-PRPP complex
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, CHLORIDE ION, ForT-PRPP complex, ...
著者Naismith, J.H, Gao, S.
登録日2020-04-18
公開日2020-05-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Uncovering the chemistry of C-C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex.
Chem.Commun.(Camb.), 56, 2020
6GOW
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BU of 6gow by Molmil
Crystal structure of the flagellin-FliS complex from Bacillus subtilis crystallized in spacegroup P22121
分子名称: Flagellar secretion chaperone FliS, Flagellin
著者Altegoer, F, Bange, G.
登録日2018-06-04
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献FliS/flagellin/FliW heterotrimer couples type III secretion and flagellin homeostasis.
Sci Rep, 8, 2018

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件を2025-07-09に公開中

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