7VLU
| Structure of SUR2A in complex with Mg-ATP/ADP and P1075 | 分子名称: | 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Chen, L, Ding, D. | 登録日 | 2021-10-05 | 公開日 | 2022-05-18 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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7VWC
| Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1 | 分子名称: | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2021-11-10 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
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7VX8
| Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2021-11-12 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
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7VLR
| Structure of SUR2B in complex with Mg-ATP/ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Chen, L, Ding, D. | 登録日 | 2021-10-05 | 公開日 | 2022-05-18 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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7W01
| Cryo-EM structure of nucleotide-free ABCA3 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xie, T, Zhang, Z.K, Yue, J, Gong, X. | 登録日 | 2021-11-17 | 公開日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the human surfactant lipid transporter ABCA3. Sci Adv, 8, 2022
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7W02
| Cryo-EM structure of ATP-bound ABCA3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Xie, T, Zhang, Z.K, Yue, J, Gong, X. | 登録日 | 2021-11-17 | 公開日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the human surfactant lipid transporter ABCA3. Sci Adv, 8, 2022
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7O11
| ABC transporter NosDFY, nucleotide-free in GDN, R-domain 1 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O14
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 1 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O17
| ABC transporter NosDFY E154Q, ATP-bound in lipid nanodisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O10
| ABC transporter NosDFY, nucleotide-free in GDN, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O15
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O0Y
| ABC transporter NosDFY, nucleotide-free in GDN | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O16
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O12
| ABC transporter NosDFY, AMPPNP-bound in GDN | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ABC transporter ATP-binding protein NosF, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7N59
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7N5A
| Structure of AtAtm3 in the closed conformation | 分子名称: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Fan, C, Rees, D.C. | 登録日 | 2021-06-05 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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7N58
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7N5B
| Structure of AtAtm3 in the outward-facing conformation | 分子名称: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Fan, C, Rees, D.C. | 登録日 | 2021-06-05 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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7TCG
| BceAB nucleotide-free conformation | 分子名称: | 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB | 著者 | George, N.L, Orlando, B.J. | 登録日 | 2021-12-23 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformational snapshots of the bacitracin sensing and resistance transporter BceAB. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TCH
| BceAB E169Q variant ATP-bound conformation | 分子名称: | 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, ADENOSINE-5'-TRIPHOSPHATE, Bacitracin export ATP-binding protein BceA, ... | 著者 | George, N.L, Orlando, B.J. | 登録日 | 2021-12-23 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Conformational snapshots of the bacitracin sensing and resistance transporter BceAB. Proc.Natl.Acad.Sci.USA, 119, 2022
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7M68
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7M69
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7SEL
| E. coli MsbA in complex with LPS and inhibitor G7090 (compound 3) | 分子名称: | (2E)-3-{7-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1-methylnaphthalen-2-yl}prop-2-enoic acid, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | 著者 | Payandeh, J, Koth, C.M, Verma, V.A. | 登録日 | 2021-09-30 | 公開日 | 2022-03-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.978 Å) | 主引用文献 | Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity. J.Med.Chem., 65, 2022
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7EFO
| LptB2FG-LPS from Klebsiella pneumoniae in nanodiscs | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, ... | 著者 | Luo, Q, Shi, H. | 登録日 | 2021-03-22 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Cryo-EM structures of LptB 2 FG and LptB 2 FGC from Klebsiella pneumoniae in complex with lipopolysaccharide. Biochem.Biophys.Res.Commun., 571, 2021
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7NDF
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