Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7CJ0
DownloadVisualize
BU of 7cj0 by Molmil
Crystal structure of DNAJC9 HBD in complex with H3.3-H4 dimer and MCM2 HBD
分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, GLYCEROL, ...
著者Bao, H, Huang, H.
登録日2020-07-09
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
7CIZ
DownloadVisualize
BU of 7ciz by Molmil
Crystal structure of DNAJC9 HBD helix2 in complex with H3.3-H4 dimer and MCM2 HBD
分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, Histone H3.3, ...
著者Bao, H, Huang, H.
登録日2020-07-08
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
6BHG
DownloadVisualize
BU of 6bhg by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHI
DownloadVisualize
BU of 6bhi by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHD
DownloadVisualize
BU of 6bhd by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SODIUM ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHE
DownloadVisualize
BU of 6bhe by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6BHH
DownloadVisualize
BU of 6bhh by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-11-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6WW3
DownloadVisualize
BU of 6ww3 by Molmil
Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ...
著者Liu, J, Vann, K.R, Kutateladze, T.G.
登録日2020-05-07
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure, 28, 2020
6XGC
DownloadVisualize
BU of 6xgc by Molmil
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
分子名称: 1C4 Fab heavy chain, 1C4 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Qiu, Y, Zhou, Y.
登録日2020-06-17
公開日2021-03-10
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
6E83
DownloadVisualize
BU of 6e83 by Molmil
Solution structure of ZZZ3 ZZ domain in complex with histone H3 tail
分子名称: Histone H3, ZINC ION, ZZ-type zinc finger-containing protein 3
著者Zhang, Y, Kutateladze, T.G.
登録日2018-07-27
公開日2018-09-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
6F6D
DownloadVisualize
BU of 6f6d by Molmil
The catalytic domain of KDM6B in complex with H3(17-33)K18IA21M peptide
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Histone 3 peptide H3(17-33)K18IA21M, ...
著者Jones, S.E, Olsen, L, Gajhede, M.
登録日2017-12-05
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.81810677 Å)
主引用文献Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity.
Biochemistry, 57, 2018
6U04
DownloadVisualize
BU of 6u04 by Molmil
Crystal structure of human BRPF1 PZP bound to histone H3 tail
分子名称: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2019-08-13
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
3FSS
DownloadVisualize
BU of 3fss by Molmil
Structure of the tandem PH domains of Rtt106
分子名称: GLYCEROL, Histone chaperone RTT106, MALONIC ACID
著者Su, D, Thompson, J.R, Mer, G.
登録日2009-01-11
公開日2009-12-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.432 Å)
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
7D86
DownloadVisualize
BU of 7d86 by Molmil
Crystal Structure of zebrafishPHF14-PZP
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHD finger protein 14, ...
著者Li, H, Zheng, S.
登録日2020-10-07
公開日2021-07-28
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
8BA5
DownloadVisualize
BU of 8ba5 by Molmil
Crystal structure of the DNMT3A ADD domain
分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, MAGNESIUM ION, ...
著者Linhard, V, Kunert, S, Wollenhaupt, J, Broehm, A, Schwalbe, H, Jeltsch, A.
登録日2022-10-11
公開日2022-11-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site.
Protein Sci., 32, 2023
2L43
DownloadVisualize
BU of 2l43 by Molmil
Structural basis for histone code recognition by BRPF2-PHD1 finger
分子名称: Histone H3.3,LINKER,Bromodomain-containing protein 1, ZINC ION
著者Qin, S, Zhang, J, Wu, J, Shi, Y.
登録日2010-10-01
公開日2011-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF
To be Published
6PWF
DownloadVisualize
BU of 6pwf by Molmil
Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome
分子名称: DNA (147-MER), Histone H2A, Histone H2B, ...
著者Chittori, S, Subramaniam, S.
登録日2019-07-22
公開日2019-08-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome.
Nucleic Acids Res., 47, 2019
6PWE
DownloadVisualize
BU of 6pwe by Molmil
Cryo-EM structure of nucleosome core particle
分子名称: DNA (147-MER), Histone H2A, Histone H2B, ...
著者Chittori, S, Subramaniam, S.
登録日2019-07-22
公開日2019-08-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome.
Nucleic Acids Res., 47, 2019
8P89
DownloadVisualize
BU of 8p89 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody B5
分子名称: CHLORIDE ION, Light chain H3, Nanobody B5
著者Broggini, L, Ricagno, S.
登録日2023-05-31
公開日2024-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.187 Å)
主引用文献Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
8P88
DownloadVisualize
BU of 8p88 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody C4
分子名称: CHLORIDE ION, Light Chain H3, Nanobody C4, ...
著者Broggini, L, Ricagno, S.
登録日2023-05-31
公開日2024-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.022 Å)
主引用文献Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
7MJU
DownloadVisualize
BU of 7mju by Molmil
Crystal structure of human AF10 PZP bound to histone H3 tail
分子名称: Histone H3.1,Protein AF-10, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2021-04-20
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
6J99
DownloadVisualize
BU of 6j99 by Molmil
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
分子名称: DNA (144-MER), DNA (145-MER), Histone H2A, ...
著者Yao, T, Huang, J.
登録日2019-01-22
公開日2019-02-27
最終更新日2019-04-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 29, 2019
4GND
DownloadVisualize
BU of 4gnd by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains
分子名称: Histone-lysine N-methyltransferase NSD3, ZINC ION
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
7OAQ
DownloadVisualize
BU of 7oaq by Molmil
Nanobody H3 AND C1 bound to RBD with Kent mutation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRIC ACID, ...
著者Naismith, J.H, Mikolajek, H.
登録日2021-04-20
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
7OAP
DownloadVisualize
BU of 7oap by Molmil
Nanobody H3 AND C1 bound to RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C1 nanobody, CHLORIDE ION, ...
著者Naismith, J.H, Mikolajek, H.
登録日2021-04-19
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon