PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

---

6ZU4	Human Sirt6 13-308 in complex with ADP-ribose and the activator fluvastatin 分子名称: (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid, GLYCEROL, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2020-07-21 公開日 2020-11-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structural Basis for Activation of Human Sirtuin 6 by Fluvastatin. Acs Med.Chem.Lett., 11, 2020
7TNJ	Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) 分子名称: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera 著者 Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2022-01-21 公開日 2022-04-20 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022
7TNP	Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera 著者 Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2022-01-21 公開日 2022-04-20 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022
2Y6R	Structure of the TetX monooxygenase in complex with the substrate 7- chlortetracycline 分子名称: 7-CHLOROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Volkers, G, Palm, G.J, Weiss, M.S, Wright, G.D, Hinrichs, W. 登録日 2011-01-25 公開日 2011-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis for a New Tetracycline Resistance Mechanism Relying on the Tetx Monooxygenase. FEBS Lett., 585, 2011
7TRC	Human telomerase H/ACA RNP at 3.3 Angstrom 分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... 著者 Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. 登録日 2022-01-28 公開日 2022-04-20 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
6ZY3	Cryo-EM structure of MlaFEDB in complex with phospholipid 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... 著者 Dong, C.J, Dong, H.H. 登録日 2020-07-30 公開日 2020-11-25 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB. Nat.Struct.Mol.Biol., 28, 2021
8PRY	Crystal structure of Trypanosoma cruzi glycerol kinase 分子名称: GLYCEROL, glycerol kinase 著者 Lipinski, O, Sonani, R.R, Dubin, G. 登録日 2023-07-12 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystal structure of Trypanosoma cruzi glycerol kinase in complex with glycerol To Be Published
3JRM	Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator 分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta 著者 Stadtmueller, B.M, Whitby, F.G, Hill, C.P. 登録日 2009-09-08 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural models for interactions between the 20S proteasome and its PAN/19S activators. J.Biol.Chem., 285, 2010
7QG0	Inhibitor-induced hSARM1 duplex 分子名称: NAD(+) hydrolase SARM1 著者 Zalk, R, Kahzma, T, Guez-Haddad, J. 登録日 2021-12-07 公開日 2022-12-21 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 A duplex structure of SARM1 octamers stabilized by a new inhibitor. Cell.Mol.Life Sci., 80, 2022
2I5M	Crystal structure of Bacillus subtilis cold shock protein CspB variant A46K S48R 分子名称: Cold shock protein cspB, MAGNESIUM ION 著者 Max, K.E.A, Heinemann, U. 登録日 2006-08-25 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability. J.Mol.Biol., 369, 2007
7F4S	Crystal structure of TthMTA1-PteMTA9 complex 分子名称: MT-a70 family protein, MTA9 著者 Chen, J, Liu, L. 登録日 2021-06-21 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structural basis for MTA1c-mediated DNA N6-adenine methylation Nat Commun, 13, 2022
7U06	Structure of the yeast TRAPPII-Rab11/Ypt32 complex in the closed/open state (composite structure) 分子名称: GTP-binding protein YPT32/YPT11, PALMITIC ACID, TRAPP-associated protein TCA17, ... 著者 Bagde, S.R, Fromme, J.C. 登録日 2022-02-17 公開日 2022-04-27 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of a TRAPPII-Rab11 activation intermediate reveals GTPase substrate selection mechanisms. Sci Adv, 8, 2022
7QHJ	Peptide GAKSAA in complex with human cathepsin V C25A mutant 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cathepsin L2, ... 著者 Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. 登録日 2021-12-13 公開日 2022-12-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
3K98	HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide 分子名称: (1R)-2-[(5-chloro-2,4-dihydroxyphenyl)carbonyl]-N-ethyl-2,3-dihydro-1H-isoindole-1-carboxamide, Heat shock protein HSP 90-alpha, PHOSPHATE ION 著者 Gajiwala, K.S, Davies II, J.F. 登録日 2009-10-15 公開日 2010-02-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. J.Med.Chem., 53, 2010
2NPE	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance 分子名称: ACETATE ION, Ammonia channel, SULFATE ION 著者 Lupo, D, Winkler, F.K. 登録日 2006-10-27 公開日 2006-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
2I5R	Structure of small Toprim domain-containing protein from B. stearothermophilus in complex with Mg2+ 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Rezacova, P, Borek, D, Otwinowski, Z, Joachimiak, A, Moy, S.F, Midwest Center for Structural Genomics (MCSG) 登録日 2006-08-25 公開日 2007-07-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus. Proteins, 70, 2007
5MA2	PCE reductive dehalogenase from S. multivorans in complex with 4-iodophenol 分子名称: 4-IODOPHENOL, BENZAMIDINE, GLYCEROL, ... 著者 Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. 登録日 2016-11-03 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.879 Å) 主引用文献 Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
3JTA	Structure of neuronal nitric oxide synthase heme domain in the ferrous state complexed with N~5~-[4-(methylsulfanyl)butanimidoyl]-L-ornithine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, Nitric oxide synthase, ... 著者 Li, H, Poulos, T.L. 登録日 2009-09-11 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency. J.Am.Chem.Soc., 132, 2010
2Y6Q	Structure of the TetX monooxygenase in complex with the substrate 7- Iodtetracycline 分子名称: 7-IODOTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Volkers, G, Palm, G.J, Weiss, M.S, Wright, G.D, Hinrichs, W. 登録日 2011-01-25 公開日 2011-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural Basis for a New Tetracycline Resistance Mechanism Relying on the Tetx Monooxygenase. FEBS Lett., 585, 2011
7A46	small conductance mechanosensitive channel YbiO 分子名称: Putative transport protein 著者 Flegler, V.J, Rasmussen, A, Rao, S, Wu, N, Zenobi, R, Sansom, M.S.P, Hedrich, R, Rasmussen, T, Boettcher, B. 登録日 2020-08-19 公開日 2020-11-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The MscS-like channel YnaI has a gating mechanism based on flexible pore helices. Proc.Natl.Acad.Sci.USA, 117, 2020
8POB	Crystal structure of Hen Egg White Lysozyme co-crystallized with 10 mM TbXo4-SO3 分子名称: 6-[[4-[(6-carboxypyridin-2-yl)methyl]-7-(3-sulfopropyl)-1,4,7-triazonan-1-yl]methyl]pyridine-2-carboxylic acid, CHLORIDE ION, Lysozyme C, ... 著者 Alsalman, Z, Girard, E. 登録日 2023-07-04 公開日 2024-07-10 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Influence of Chemical Modifications of the Crystallophore on Protein Nucleating Properties and Supramolecular Interactions Network. Chemistry, 30, 2024
7QFH	Peptide AYFKKVL in complex with human cathepsin V C25A mutant 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AMINO GROUP, CHLORIDE ION, ... 著者 Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. 登録日 2021-12-06 公開日 2022-12-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
3JC1	Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer 分子名称: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1) 著者 McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A. 登録日 2015-11-09 公開日 2015-12-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure and membrane remodeling activity of ESCRT-III helical polymers. Science, 350, 2015
6ZM1	Open-closed state of the Bt1762-Bt1763 levan transport system 分子名称: SusC homolog, SusD homolog 著者 White, J.B.R, van den Berg, B, Ranson, N.A. 登録日 2020-07-01 公開日 2020-11-11 最終更新日 2021-01-20 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Insights into SusCD-mediated glycan import by a prominent gut symbiont. Nat Commun, 12, 2021
8PMW	HEV gt3 P domain in complex with glycan-sensitive nAb p60.1 分子名称: ACETATE ION, Capsid protein, SULFATE ION, ... 著者 Ssebyatika, G, Krey, T. 登録日 2023-06-29 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published

<1284128512861287128812891290129112921293129412951296129712981299>