2Y6R

Structure of the TetX monooxygenase in complex with the substrate 7- chlortetracycline

Summary for 2Y6R

Entry DOI	10.2210/pdb2y6r/pdb
Related	2XDO 2XYO 2Y6Q
Descriptor	TETX2 PROTEIN, FLAVIN-ADENINE DINUCLEOTIDE, 7-CHLOROTETRACYCLINE, ... (5 entities in total)
Functional Keywords	oxidoreductase, antibiotic resistance, flavin, tigecycline, tetracycline degradation
Biological source	BACTEROIDES THETAIOTAOMICRON
Total number of polymer chains	4
Total formula weight	184463.43
Authors	Volkers, G.,Palm, G.J.,Weiss, M.S.,Wright, G.D.,Hinrichs, W. (deposition date: 2011-01-25, release date: 2011-03-23, Last modification date: 2023-12-20)
Primary citation	Volkers, G.,Palm, G.J.,Weiss, M.S.,Wright, G.D.,Hinrichs, W. Structural Basis for a New Tetracycline Resistance Mechanism Relying on the Tetx Monooxygenase. FEBS Lett., 585:1061-, 2011 Cited by PubMed: 21402075 DOI: 10.1016/J.FEBSLET.2011.03.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation