2ADA
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2AQ9
| Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP | 分子名称: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... | 著者 | Williams, A.H, Immormino, R.M, Gewirth, D.T, Raetz, C.R. | 登録日 | 2005-08-17 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AUC
| Structure of the Plasmodium MTIP-MyoA complex, a key component of the parasite invasion motor | 分子名称: | Myosin A, Myosin A Tail Interacting Protein | 著者 | Bosch, J, Turley, S, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2005-08-27 | 公開日 | 2006-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AXG
| The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation | 分子名称: | 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ... | 著者 | Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R. | 登録日 | 2005-09-05 | 公開日 | 2005-11-29 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation J.Exp.Med., 202, 2005
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2AYV
| Crystal structure of a putative ubiquitin-conjugating enzyme E2 from Toxoplasma gondii | 分子名称: | UNKNOWN ATOM OR ION, ubiquitin-conjugating enzyme E2 | 著者 | Tempel, W, Dong, A, Zhao, Y, Lew, J, Alam, Z, Melone, M, Wasney, G, Kozieradzki, I, Vedadi, M, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | 登録日 | 2005-09-08 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
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1YT0
| Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ... | 著者 | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | 登録日 | 2005-02-09 | 公開日 | 2005-06-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE J.Biol.Chem., 280, 2005
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1YT2
| Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N APO CRYSTAL | 分子名称: | Endoplasmin, TETRAETHYLENE GLYCOL | 著者 | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | 登録日 | 2005-02-09 | 公開日 | 2005-06-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE J.Biol.Chem., 280, 2005
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2AQU
| Structure of HIV-1 protease bound to atazanavir | 分子名称: | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, HIV-1 Protease | 著者 | Clemente, J.C, Coman, R.M, Thiaville, M.M, Janka, L.K, Jeung, J.A, Nukoolkarn, S, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Leelamanit, W, Goodenow, M.M, Dunn, B.M. | 登録日 | 2005-08-18 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry, 45, 2006
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2AZR
| Crystal structure of PTP1B with Bicyclic Thiophene inhibitor | 分子名称: | 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-12 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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2AXF
| The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation | 分子名称: | 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ... | 著者 | Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R. | 登録日 | 2005-09-05 | 公開日 | 2005-11-29 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation J.Exp.Med., 202, 2005
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2B07
| Crystal structure of PTP1B with Tricyclic Thiophene inhibitor. | 分子名称: | 6-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}-3-(CARBOXYMETHOXY)THIENO[3,2-B][1]BENZOTHIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1 | 著者 | Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J. | 登録日 | 2005-09-13 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem., 14, 2006
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2B9L
| Crystal structure of prophenoloxidase activating factor-II from the beetle Holotrichia diomphalia | 分子名称: | CALCIUM ION, SULFATE ION, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Piao, S, Song, Y.-L, Park, S.Y, Lee, B.L, Oh, B.-H, Ha, N.-C. | 登録日 | 2005-10-12 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a clip-domain serine protease and functional roles of the clip domains. Embo J., 24, 2005
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2AP8
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2AP7
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2BZM
| Solution structure of the primary host recognition region of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | 登録日 | 2005-08-18 | 公開日 | 2006-03-22 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure. J.Biol.Chem., 281, 2006
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2BQW
| CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH COMPOUND 45 | 分子名称: | 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X, ... | 著者 | Nazare, M, Will, D.W, Matter, H, Schreuder, H, Ritter, K, Urmann, M, Essrich, M, Bauer, A, Wagner, M, Czech, J, Laux, V, Wehner, V. | 登録日 | 2005-04-28 | 公開日 | 2006-04-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-Ray Crystallography. J.Med.Chem., 48, 2005
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8RNH
| Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Murdolo, L.D, Maddumaage, J, Gras, S. | 登録日 | 2024-01-10 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8ROO
| Crystal structure of HLA B*18:01 in complex with YERMCNIL, an 8-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Influenza A derived peptide/Nucleoprotein, ... | 著者 | Murdolo, L.D, Maddumage, J.C, Gras, S. | 登録日 | 2024-01-11 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8ROP
| Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | 著者 | Murdolo, L.D, Maddumage, J.C, Gras, S. | 登録日 | 2024-01-12 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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8SC8
| Structure of PI3KG in complex with MTX-531 | 分子名称: | N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | 著者 | Whitehead, C.E, Leopold, J. | 登録日 | 2023-04-05 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.687 Å) | 主引用文献 | Structure of PI3KG in complex with MTX-531 To Be Published
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8SC7
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8RJ6
| E. coli adenylate kinase in complex with ATP and AMP and Mg2+ as a result of enzymatic AP4A hydrolysis. | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | 登録日 | 2023-12-20 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase. Sci Adv, 10, 2024
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8RJ4
| E. coli adenylate kinase in complex with two ADP molecules and Mg2+ as a result of enzymatic AP4A hydrolysis | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase, CHLORIDE ION, ... | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | 登録日 | 2023-12-20 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase. Sci Adv, 10, 2024
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8RJ9
| E. coli adenylate kinase Asp84Ala variant in complex with two ADP molecules as a result of enzymatic AP4A hydrolysis. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | 登録日 | 2023-12-20 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase. Sci Adv, 10, 2024
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4C9T
| BACTERIAL CHALCONE ISOMERASE IN open CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SelenoMet derivative | 分子名称: | CHALCONE ISOMERASE, CHLORIDE ION, GLYCEROL, ... | 著者 | Thomsen, M, Palm, G.J, Hinrichs, W. | 登録日 | 2013-10-03 | 公開日 | 2014-10-22 | 最終更新日 | 2015-04-22 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure and Catalytic Mechanism of the Evolutionarily Unique Bacterial Chalcone Isomerase Acta Crystallogr.,Sect.D, 71, 2015
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