2AQ9

Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP

Summary for 2AQ9

• Entry DOI: 10.2210/pdb2aq9/pdb
• Related: 1LXA
• Descriptor: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, peptide inhibitor, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: lpxa, peptide inhibitor, acyl acp, acp, udp-glcnac, lipid a, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A722
• Total number of polymer chains: 2
• Total formula weight: 32003.74

Authors

Williams, A.H.,Immormino, R.M.,Gewirth, D.T.,Raetz, C.R. (deposition date: 2005-08-17, release date: 2006-06-27, Last modification date: 2023-08-23)

• Primary citation: Williams, A.H.,Immormino, R.M.,Gewirth, D.T.,Raetz, C.R.; Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.; Proc.Natl.Acad.Sci.Usa, 103:10877-10882, 2006; PubMed: 16835299; DOI: 10.1073/pnas.0604465103

Experimental method

X-RAY DIFFRACTION (1.8 Å)