7A1K
 
 | | FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-((9,9-dimethyl-9H-fluoren-2-yl)methyl)-2-oxoglutarate | | 分子名称: | 3-((9,9-dimethyl-9H-fluoren-2-yl)methyl)-2-oxoglutarate, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-08-13 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | 2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
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7AC1
 | | Solution structure of the TAF4-RST domain | | 分子名称: | Transcription initiation factor TFIID subunit 4 | | 著者 | Staby, L, Davidsen, R, Bugge, K, Skriver, K, Kragelund, B.B. | | 登録日 | 2020-09-09 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | alpha alpha-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes.
J.Biol.Chem., 298, 2022
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8GO8
 | | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 | | 分子名称: | Beta-arrestin-1, C5a anaphylatoxin chemotactic receptor 1, Fab30 heavy chain, ... | | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | | 登録日 | 2022-08-24 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation.
Mol.Cell, 83, 2023
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8GP3
 | | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 | | 分子名称: | Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ... | | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | | 登録日 | 2022-08-25 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation.
Mol.Cell, 83, 2023
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6XRW
 | | Chromosomal ParDE TA system from P. aeruginosa | | 分子名称: | BENZAMIDINE, GLYCEROL, NONAETHYLENE GLYCOL, ... | | 著者 | Bourne, C.R, Snead, K.J, Thomas, L.M. | | 登録日 | 2020-07-13 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kinetics.
Biochemistry, 61, 2022
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5XOD
 | | Crystal structure of human Smad2-Ski complex | | 分子名称: | Mothers against decapentaplegic homolog 2, Ski oncogene | | 著者 | Miyazono, K, Moriwaki, S, Ito, T, Tanokura, M. | | 登録日 | 2017-05-27 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors
Sci Signal, 11, 2018
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1RDT
 | | Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer | | 分子名称: | (S)-(2E)-3[4-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)TETRAHYDRO-1-BENZOFURAN-2-YL]-2-PROPENOIC ACID, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, LxxLL motif coactivator, ... | | 著者 | Haffner, C.D, Lenhard, J.M, Miller, A.B, McDougald, D.L, Dwornik, K, Ittoop, O.R, Gampe Jr, R.T, Xu, H.E, Blanchard, S, Montana, V.G. | | 登録日 | 2003-11-06 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based design of potent retinoid X receptor alpha agonists.
J.Med.Chem., 47, 2004
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5XTH
 | | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | | 著者 | Gu, J, Wu, M, Yang, M. | | 登録日 | 2017-06-19 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
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5U4J
 | | Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ... | | 著者 | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | | 登録日 | 2016-12-04 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
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6ZRB
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1RK3
 | | crystal structure of the rat vitamin D receptor ligand binding domain complexed with 1,25-dihydroxyvitamin D3 and a synthetic peptide containing the NR2 box of DRIP 205 | | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor | | 著者 | Vanhooke, J.L, M Benning, M, Bauer, C.B, Pike, J.W, DeLuca, H.F. | | 登録日 | 2003-11-20 | | 公開日 | 2004-04-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide
Biochemistry, 43, 2004
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4G93
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6Y20
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6Y6K
 | | Cryo-EM structure of a Phenuiviridae L protein | | 分子名称: | MAGNESIUM ION, RNA-dependent RNA polymerase | | 著者 | Vogel, D, Thorkelsson, S.R, Quemin, E, Meier, K, Kouba, T, Gogrefe, N, Busch, C, Reindl, S, Guenther, S, Cusack, S, Gruenewald, K, Rosenthal, M. | | 登録日 | 2020-02-26 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 48, 2020
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6XZR
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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5XVW
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5CFK
 | | Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution | | 分子名称: | Proliferating cell nuclear antigen,Proliferating cell nuclear antigen | | 著者 | Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2015-07-08 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
To Be Published
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6XZQ
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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5U93
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3GJ6
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5XGE
 | | Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861 | | 著者 | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | | 登録日 | 2017-04-13 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
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2BAW
 | | Human Nuclear Receptor-Ligand Complex 1 | | 分子名称: | Peroxisome proliferator activated receptor delta, VACCENIC ACID, heptyl beta-D-glucopyranoside | | 著者 | Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N. | | 登録日 | 2005-10-15 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Reevaluation of the PPAR-beta/delta Ligand Binding Domain Model Reveals Why It Exhibits the Activated Form
Mol.Cell, 21, 2006
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5XVL
 | | Crystal structure of AL2 PAL domain | | 分子名称: | PHD finger protein ALFIN-LIKE 2, SULFATE ION | | 著者 | Peng, L, Wang, L.L, Huang, Y. | | 登録日 | 2017-06-28 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.629 Å) | | 主引用文献 | Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
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5U9E
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7RGS
 | | The crystal structure of RocC, containing FinO domain, 24-126 | | 分子名称: | Repressor of competence, RNA Chaperone | | 著者 | Kim, H.J, Edwards, R.A, Glover, J.N.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
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