PDB: 183105 件ウェブページステータス検索Chemie searchBIRD

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4QR8	Crystal Structure of E coli pepQ 分子名称: MAGNESIUM ION, Xaa-Pro dipeptidase 著者 Pingwei, L. 登録日 2014-06-30 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural basis of substrate selectivity of E. coli prolidase. Plos One, 9, 2014
1Q0H	Crystal structure of selenomethionine-labelled DXR in complex with fosmidomycin 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, CITRIC ACID, ... 著者 Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C. 登録日 2003-07-16 公開日 2004-07-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation. J.Mol.Biol., 345, 2005
4R9M	Crystal structure of spermidine N-acetyltransferase from Escherichia coli 分子名称: MAGNESIUM ION, Spermidine N(1)-acetyltransferase 著者 Filippova, E.V, Minasov, G, Kiryukhina, O, Shuvalova, L, Grimshaw, S, Wolfe, A.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-09-05 公開日 2014-11-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli. Acta Crystallogr D Struct Biol, 75, 2019
1Q39	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The WT enzyme at 2.8 resolution. 分子名称: CALCIUM ION, Endonuclease VIII, ZINC ION 著者 Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. 登録日 2003-07-29 公開日 2004-08-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility. Nucleic Acids Res., 33, 2005
4H2J	Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1354 分子名称: N~4~-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N~1~-[4-(1H-imidazol-2-yl)phenyl]-2-nitrobenzene-1,4-dicarboxamide, Undecaprenyl pyrophosphate synthase 著者 Zhu, W, Oldfield, E. 登録日 2012-09-12 公開日 2012-12-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
2KGD	NMR Solution Structures of 3-oxo-butyl-ACP, an intermediate mimic from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-08 公開日 2009-04-14 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
2OZ7	Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate 分子名称: Androgen receptor, CYPROTERONE ACETATE 著者 Bohl, C.E, Wu, Z, Miller, D.D, Bell, C.E, Dalton, J.T. 登録日 2007-02-25 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design. J.Biol.Chem., 282, 2007
1IBK	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN 分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. 登録日 2001-03-28 公開日 2001-05-04 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 2001
4RFN	Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ... 著者 Gohain, N, Tolbert, W.D, Pazgier, M. 登録日 2014-09-26 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
1D6Z	CRYSTAL STRUCTURE OF THE AEROBICALLY FREEZE TRAPPED RATE-DETERMINING CATALYTIC INTERMEDIATE OF E. COLI COPPER-CONTAINING AMINE OXIDASE. 分子名称: 2-PHENYLETHYLAMINE, CALCIUM ION, COPPER (II) ION, ... 著者 Wilmot, C.M, Hajdu, J, McPherson, M.J, Knowles, P.F, Phillips, S.E.V. 登録日 1999-10-16 公開日 2000-02-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Visualization of dioxygen bound to copper during enzyme catalysis. Science, 286, 1999
1PNK	PENICILLIN ACYLASE HAS A SINGLE-AMINO-ACID CATALYTIC CENTRE 分子名称: CALCIUM ION, PENICILLIN AMIDOHYDROLASE 著者 Duggleby, H.J, Moody, P.C.E. 登録日 1995-03-16 公開日 1996-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Penicillin acylase has a single-amino-acid catalytic centre. Nature, 373, 1995
3ZJ4	Neurospora Crassa Catalase-3 expressed in E. coli, triclinic form. 分子名称: CATALASE-3, PROTOPORPHYRIN IX CONTAINING FE 著者 Zarate-Romero, A, Rudino-Pinera, E. 登録日 2013-01-17 公開日 2013-07-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.098 Å) 主引用文献 Conformational Stability and Crystal Packing: Polymorphism in Neurospora Crassa Cat-3 Acta Crystallogr.,Sect.F, 69, 2013
1I5O	CRYSTAL STRUCTURE OF MUTANT R105A OF E. COLI ASPARTATE TRANSCARBAMOYLASE 分子名称: ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN, ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... 著者 Macol, C.P, Tsuruta, H, Stec, B, Kantrowitz, E.R. 登録日 2001-02-28 公開日 2001-05-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Direct structural evidence for a concerted allosteric transition in Escherichia coli aspartate transcarbamoylase. Nat.Struct.Biol., 8, 2001
3AX7	Bovine Xanthine Oxidase, protease cleaved form 分子名称: 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ... 著者 Ishikita, H, Eger, B.T, Pai, E.F, Okamoto, K, Nishino, T. 登録日 2011-03-30 公開日 2012-02-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Protein conformational gating of enzymatic activity in xanthine oxidoreductase J.Am.Chem.Soc., 134, 2012
3AX9	Bovine xanthine oxidase, protease cleaved form 分子名称: 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ... 著者 Ishikita, H, Eger, B.T, Pai, E.F, Okamoto, K, Nishino, T. 登録日 2011-03-31 公開日 2012-02-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Protein conformational gating of enzymatic activity in xanthine oxidoreductase J.Am.Chem.Soc., 134, 2012
3ZJ5	NEUROSPORA CRASSA CATALASE-3 EXPRESSED IN E. COLI, ORTHORHOMBIC FORM. 分子名称: 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, CATALASE-3, ... 著者 Zarate-Romero, A, Rudino-Pinera, E. 登録日 2013-01-17 公開日 2013-07-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Conformational Stability and Crystal Packing: Polymorphism in Neurospora Crassa Cat-3 Acta Crystallogr.,Sect.F, 69, 2013
4GON	Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM 分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl][2-(1H-indol-3-yl)ethyl]amino}-5'-deoxyadenosine, DNA adenine methylase 著者 Harmer, J.E, Roach, P.L. 登録日 2012-08-20 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic To be published
4H2O	Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1248 分子名称: 2-{[3-(decyloxy)benzoyl]amino}-5-nitrobenzoic acid, Undecaprenyl pyrophosphate synthase 著者 Zhu, W, Oldfield, E. 登録日 2012-09-13 公開日 2012-12-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
7KWT	X-ray Crystal Structure of PlyCB Mutant Y28H 分子名称: PlyCB 著者 Williams, D.E, Broendum, S.S, Hayes, B.K, Drinkwater, N, McGowan, S. 登録日 2020-12-02 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus. Mol.Microbiol., 116, 2021
3B4N	Crystal Structure Analysis of Pectate Lyase PelI from Erwinia chrysanthemi 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Endo-pectate lyase, ... 著者 Creze, C, Castang, S, Derivery, E, Haser, R, Shevchik, V, Gouet, P. 登録日 2007-10-24 公開日 2008-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The Crystal Structure of Pectate Lyase PelI from Soft Rot Pathogen Erwinia chrysanthemi in Complex with Its Substrate. J.Biol.Chem., 283, 2008
4JRQ	Crystal structure of E. coli Exonuclease I in complex with a 5cy-dA13 oligonucleotide 分子名称: 5cy-dA13, Exodeoxyribonuclease I, SULFATE ION 著者 Bell, C.E. 登録日 2013-03-21 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of Escherichia coli exonuclease I in complex with single-stranded DNA provide insights into the mechanism of processive digestion. Nucleic Acids Res., 41, 2013
4GOM	Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Aza-SAM 分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl]amino}-5'-deoxyadenosine, DNA adenine methylase 著者 Harmer, J.E, Roach, P.L. 登録日 2012-08-20 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic To be published
1ZA7	The crystal structure of salt stable cowpea cholorotic mottle virus at 2.7 angstroms resolution. 分子名称: Coat protein 著者 Bothner, B, Speir, J.A, Qu, C, Willits, D.A, Young, M.J, Johnson, J.E. 登録日 2005-04-05 公開日 2006-03-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enhanced local symmetry interactions globally stabilize a mutant virus capsid that maintains infectivity and capsid dynamics. J.Virol., 80, 2006
7L7P	Crystal structure of HCV NS3/4A D168A protease in complex with CH-24 分子名称: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2020-12-29 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J.Med.Chem., 64, 2021
7L7O	Crystal structure of HCV NS3/4A D168A protease in complex with NR04-49 分子名称: (1R,3r,5S)-bicyclo[3.1.0]hexan-3-yl [(2R,6S,12Z,13aS,14aR,16aS)-2-{[6-methoxy-3-(trifluoromethyl)quinoxalin-2-yl]oxy}-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, 1,2-ETHANEDIOL, NS3/4A protease, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2020-12-29 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J.Med.Chem., 64, 2021

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