PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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5ZJD	Lactate dehydrogenase with NADH and MLA 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, MALONATE ION 著者 Han, C.W, Jang, S.B. 登録日 2018-03-20 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid. Cancers (Basel), 11, 2019
2X80	P450 BM3 F87A in complex with DMSO 分子名称: BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Kuper, J, Wong, T.S, Roccatano, D, Wilmanns, M, Schwaneberg, U. 登録日 2010-03-05 公開日 2011-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase. Acta Crystallogr.,Sect.F, 68, 2012
6GHY	Structure of Lytic Transglycosylase MltE inactive mutant E64Q from E.coli 分子名称: DI(HYDROXYETHYL)ETHER, Endo-type membrane-bound lytic murein transglycosylase A 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2018-05-09 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli. Biochemistry, 57, 2018
4NHQ	X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (5 days) 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 Petruk, A.A, Bikiel, D.E, Vergara, A, Merlino, A. 登録日 2013-11-05 公開日 2014-09-17 最終更新日 2015-06-24 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Interaction between proteins and Ir based CO releasing molecules: mechanism of adduct formation and CO release. Inorg.Chem., 53, 2014
5ZO0	Neutron structure of xylanase at pD5.4 分子名称: Endo-1,4-beta-xylanase 2 著者 Wan, Q, Li, Z.H. 登録日 2018-04-12 公開日 2019-05-15 最終更新日 2023-11-22 実験手法 NEUTRON DIFFRACTION (1.648 Å) 主引用文献 Neutron structure of xylanase at pD5.4 To be published
4NKW	Human steroidogenic cytochrome P450 17A1 mutant A105L with substrate pregnenolone 分子名称: (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase 著者 Scott, E.E, Petrunak, E.P. 登録日 2013-11-13 公開日 2014-10-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates. J.Biol.Chem., 289, 2014
2GR3	Crystal structure of Ferredoxin reductase, BphA4 (oxidized form) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLYCEROL, ... 著者 Senda, T, Senda, M. 登録日 2006-04-22 公開日 2007-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
4RRZ	Crystal Structure of Apo Murine H90W Cyclooxygenase-2 Complexed with Lumiracoxib 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Prostaglandin G/H synthase 2, ... 著者 Xu, S, Blobaum, A.L, Banerjee, S, Marnett, L.J. 登録日 2014-11-06 公開日 2015-04-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.569 Å) 主引用文献 Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290, 2015
5YWL	SsCR_L211H 分子名称: Protein induced by osmotic stress 著者 Shang, Y.P, Chen, Q, Li, A.T, Yu, H.L, Xu, J.H. 登録日 2017-11-29 公開日 2019-03-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering. J.Biotechnol., 308, 2020
4RXZ	Crystal Structure of MDMX phosporylated Tyr99 in complex with a 12-mer peptide 分子名称: 12-MER PEPTIDE INHIBITOR, Protein Mdm4 著者 Pazgier, M, Gohain, N, Tolbert, W.D. 登録日 2014-12-12 公開日 2015-07-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis of how stress-induced MDMX phosphorylation activates p53. Oncogene, 35, 2016
2JIC	High resolution structure of xylanase-II from one micron beam experiment 分子名称: XYLANASE-II 著者 Moukhametzianov, R, Burghammer, M, Edwards, P.C, Petitdemange, S, Popov, D, Fransen, M, Schertler, G.F, Riekel, C. 登録日 2007-02-27 公開日 2008-05-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein Crystallography with a Micrometre-Sized Synchrotron-Radiation Beam. Acta Crystallogr.,Sect.D, 64, 2008
6HG8	Crystal structure of the R460G disease-causing mutant of the human dihydrolipoamide dehydrogenase. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, mitochondrial, ... 著者 Ambrus, A, Szabo, E, Weichsel, A, Bui, D, Wilk, P, Torocsik, B, Weiss, M.S, Montfort, W.R, Jordan, F, Adam-Vizi, V. 登録日 2018-08-22 公開日 2019-09-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structure of the R460G disease-causing mutant of the human dihydrolipoamide dehydrogenase. To Be Published
6GLG	Crystal structure of hMTH1 F27A in complex with LW14 in the presence of acetate 分子名称: 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... 著者 Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. 登録日 2018-05-23 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.313 Å) 主引用文献 hMTH1 F27A in complex with LW14 To Be Published
6GLQ	Crystal structure of hMTH1 N33G in complex with LW14 in the absence of acetate 分子名称: 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. 登録日 2018-05-23 公開日 2019-02-20 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 hMTH1 N33G in complex with LW14. To Be Published
6HHN	Crystal structure of L-rhamnose mutarotase FA22100 from Formosa agariphila 分子名称: L-rhamnose mutarotase 著者 Roret, T, Prechoux, A, Michel, G, Czjzek, M. 登録日 2018-08-28 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan. Nat.Chem.Biol., 15, 2019
6GLM	Crystal structure of hMTH1 N33A in complex with LW14 in the absence of acetate 分子名称: 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. 登録日 2018-05-23 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 hMTH1 N33A in complex with LW14 To Be Published
2WHW	Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase 分子名称: CYCLOTRIDECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Li, S, Chaulagain, M.R, Knauff, A.R, Podust, L.M, Montgomery, J, Sherman, D.H. 登録日 2009-05-07 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-Oxygenase. Proc.Natl.Acad.Sci.USA, 106, 2009
6GLS	Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the absence of acetate 分子名称: 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. 登録日 2018-05-23 公開日 2019-02-20 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 hMTH1 N33G in complex with TH scaffold 1. To Be Published
2WKN	gamma lactamase from Delftia acidovorans 分子名称: FORMAMIDASE, ZINC ION 著者 Isupov, M.N, Line, K, Gonsalvez, I.S, Gange-Harris, P, Lanzotti, M, Saneei, V, Littlechild, J.A. 登録日 2009-06-16 公開日 2010-09-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 The Structure of Gamma Lactamase from Delftia Acidovorans To be Published
7Y8L	Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole 分子名称: 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. 登録日 2022-06-24 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
6HYC	The structure of full-length human phenylalanine hydroxylase in complex with the cofactor and negative regulator tetrahydrobiopterin 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, Phenylalanine-4-hydroxylase 著者 Alcorlo Pages, M, Flydal, I.M. 登録日 2018-10-19 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proc.Natl.Acad.Sci.USA, 116, 2019
2WIL	AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Carletti, E, Aurbek, N, Gillon, E, Loiodice, M, Nicolet, Y, Fontecilla, J, Masson, P, Thiermann, H, Nachon, F, Worek, F. 登録日 2009-05-12 公開日 2009-05-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure-Activity Analysis of Aging and Reactivation of Human Butyrylcholinesterase Inhibited by Analogues of Tabun Biochem.J., 421, 2009
7Y9J	Crystal structure of P450 BM3-TMK from Bacillus megaterium in complex with 5-nitro-1,2-benzisoxazole 分子名称: 5-nitro-1,2-benzoxazole, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. 登録日 2022-06-24 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Engineering of a P450-based Kemp eliminase with a new mechanism Chinese J Catal, 47, 2023
4NC5	Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate) 分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, PHOSPHATE ION, Sialidase-2 著者 Buchini, S, Gallat, F.-X, Greig, I.R, Kim, J.-H, Wakatsuki, S, Chavas, L.M.G, Withers, S.G. 登録日 2013-10-24 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.513 Å) 主引用文献 Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights. Angew.Chem.Int.Ed.Engl., 53, 2014
7Y8M	Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole 分子名称: 2-[2,5-bis(fluoranyl)phenyl]pyrrolidine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, reductase 著者 Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. 登録日 2022-06-24 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022

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