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8JKN
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif
分子名称: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKO
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
3WC4
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Crystal structure of UDP-glucose: anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea
分子名称: ACETATE ION, GLYCEROL, UDP-glucose:anthocyanidin 3-O-glucosyltransferase
著者Hiromoto, T, Honjo, E, Tamada, T, Kuroki, R.
登録日2013-05-24
公開日2013-10-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of UDP-glucose:anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea
J.SYNCHROTRON RADIAT., 20, 2013
3B6Y
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Crystal Structure of the Second HIN-200 Domain of Interferon-Inducible Protein 16
分子名称: Gamma-interferon-inducible protein Ifi-16, SULFATE ION
著者Liao, J.C.C, Lam, R, Ravichandran, M, Duan, S, Tempel, W, Chirgadze, N.Y, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2007-10-29
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure Analysis of the Second HIN Domain of IFI16.
To be Published
3M66
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Crystal structure of human Mitochondrial Transcription Termination Factor 3
分子名称: mTERF domain-containing protein 1, mitochondrial
著者Spahr, H, Samuelsson, T, Hallberg, B.M, Gustafsson, C.M.
登録日2010-03-15
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain.
Biochem.Biophys.Res.Commun., 397, 2010
4QGU
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BU of 4qgu by Molmil
protein domain complex with ssDNA
分子名称: DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3'), Gamma-interferon-inducible protein 16
著者Ni, X, Ru, H, Zhao, L, Shaw, N, Ding, W, Songying, O, Liu, Z.-J.
登録日2014-05-25
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
3SZR
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Crystal structure of modified nucleotide-free human MxA
分子名称: Interferon-induced GTP-binding protein Mx1
著者Gao, S, Daumke, O.
登録日2011-07-19
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function.
Immunity, 35, 2011
3LJB
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Structural basis of oligomerisation in the MxA stalk
分子名称: Interferon-induced GTP-binding protein Mx1
著者Gao, S, Daumke, O.
登録日2010-01-26
公開日2010-05-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Nature, 465, 2010
3RLN
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Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors
分子名称: Gamma-interferon-inducible protein 16
著者Jin, T.C, Xiao, T.
登録日2011-04-19
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
4D5N
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Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
分子名称: CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1
著者Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
登録日2014-11-06
公開日2015-02-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
3BQO
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BU of 3bqo by Molmil
Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex
分子名称: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1
著者Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
登録日2007-12-20
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
1DG3
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STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM
分子名称: PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
著者Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
登録日1999-11-23
公開日2000-10-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
1G9O
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FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
分子名称: NHE-RF
著者Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
登録日2000-11-26
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
1F5N
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HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.
分子名称: INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A.
登録日2000-06-15
公開日2000-09-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
2B8W
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Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP/AlF4
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, ...
著者Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
登録日2005-10-10
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B92
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Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Interferon-induced guanylate-binding protein 1, ...
著者Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
登録日2005-10-10
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2D4H
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BU of 2d4h by Molmil
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1
著者Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
登録日2005-10-19
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
3QU3
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BU of 3qu3 by Molmil
Crystal structure of IRF-7 DBD apo form
分子名称: 1,2-ETHANEDIOL, Interferon regulatory factor 7, SODIUM ION
著者De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K.
登録日2011-02-23
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
2LOQ
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BU of 2loq by Molmil
Backbone structure of human membrane protein FAM14B (Interferon alpha-inducible protein 27-like protein 1)
分子名称: Interferon alpha-inducible protein 27-like protein 1
著者Klammt, C, Chui, E.J, Maslennikov, I, Kwiatkowski, W, Choe, S.
登録日2012-01-26
公開日2012-05-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
1ZOQ
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BU of 1zoq by Molmil
IRF3-CBP complex
分子名称: CREB-binding protein, Interferon regulatory factor 3
著者Qin, B, Lin, K.
登録日2005-05-13
公開日2006-03-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of IRF-3 in complex with CBP.
Structure, 13, 2005
7RGL
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BU of 7rgl by Molmil
HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, INTERFACE-CENTERED
分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Burrell, A.L, Kollman, J.M.
登録日2021-07-15
公開日2022-01-12
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
7RFI
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HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, INTERFACE-CENTERED
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ...
著者Burrell, A.L, Kollman, J.M.
登録日2021-07-14
公開日2022-01-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
7RGQ
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HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
著者Burrell, A.L, Kollman, J.M.
登録日2021-07-15
公開日2022-01-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
3BJK
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Crystal structure of HI0827, a hexameric broad specificity acyl-coenzyme A thioesterase: The Asp44Ala mutant enzyme
分子名称: 1,2-ETHANEDIOL, Acyl-CoA thioester hydrolase HI0827, CITRIC ACID
著者Willis, M.A, Herzberg, O, Structure 2 Function Project (S2F)
登録日2007-12-04
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of YciA from Haemophilus influenzae (HI0827), a Hexameric Broad Specificity Acyl-Coenzyme A Thioesterase.
Biochemistry, 47, 2008
6MKZ
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Crystal structure of murine 4-1BB/4-1BBL complex
分子名称: Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bitra, A, Zajonc, D.M, Doukov, T.
登録日2018-09-26
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
J. Biol. Chem., 294, 2019

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